DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment AstA-R2 and Ltb4r1

DIOPT Version :9

Sequence 1:	NP_001263042.1	Gene:	AstA-R2 / 43393	FlyBaseID:	FBgn0039595	Length:	357	Species:	Drosophila melanogaster
Sequence 2:	NP_032545.1	Gene:	Ltb4r1 / 16995	MGIID:	1309472	Length:	351	Species:	Mus musculus

Alignment Length:	298	Identity:	78/298 - (26%)
Similarity:	136/298 - (45%)	Gaps:	53/298 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 LPWIVGFFFGVIAITGFFGNLLVILVVVFNNNMRSTTNLMIVNLAAADLMFVILCIPFTATDYMV 101
            ||.::   ..|....|..||..|:..::.....|:.|.|:::|||.|||. |:|..||.......
Mouse    22 LPIVL---LSVALAVGLPGNSFVVWSILKRMQKRTVTALLVLNLALADLA-VLLTAPFFLHFLAR 82

  Fly   102 YYWPYGRFWCRSVQYLIVVTAFASIYTLVLMSIDRFLAVVHPIRSRMMRTENITLIAIVTLWIVV 166
            ..|.:....||...|:..::.:||:..:.:||:||.|||..|..|:.:||:......:..:|:|.
Mouse    83 GTWSFREMGCRLCHYVCGISMYASVLLITIMSLDRSLAVARPFMSQKVRTKAFARWVLAGIWVVS 147

  Fly   167 LVVSVPVAFTHDV---------VVDYDAKKNITYGMCTFTTNDFLGPRTYQVTF-FISSYLLPLM 221
            .::::||.....|         ..:|..|::                :.:.:.| .|:.:|||.:
Mouse   148 FLLAIPVLVYRTVKWNNRTLICAPNYPNKEH----------------KVFHLLFEAITGFLLPFL 196

  Fly   222 IISGLYMRMIMRLWRQGTGVRMSKESQRGRKRVTRLVVVVVIAFASLWLPVQLILLLKSLDVI-- 284
            .:...|         ...|.|:.....|..:|..||||::::|||:.|||..|:.|:::...:
Mouse   197 AVVASY---------SDIGRRLQARRFRRSRRTGRLVVLIILAFAAFWLPYHLVNLVEAGRTVAG 252

  Fly   285 -ETNT-------LTKLVIQVTAQTLAYSSSCINPLLYA 314
             :.|:       |.:.|:    ..||:.||.:||:|||
Mouse   253 WDKNSPAGQRLRLARYVL----IALAFLSSSVNPVLYA 286

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
AstA-R2	NP_001263042.1	7tm_4	47..>164	CDD:304433	35/116 (30%)
AstA-R2	NP_001263042.1	7tm_1	55..313	CDD:278431	71/277 (26%)
Ltb4r1	NP_032545.1	7tm_1	37..285	CDD:278431	71/277 (26%)
Ltb4r1	NP_032545.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	311..351
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167837210
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.930