Protein Alignment AstA-R2 and Gpr83

DIOPT Version :10

• Sequence 1: NP_524544.1
• Gene: AstA-R2 / 43393
• FlyBaseID: FBgn0039595
• Length: 357
• Species: Drosophila melanogaster
• Sequence 2: XP_030099918.1
• Gene: Gpr83 / 14608
• MGIID: 95712
• Length: 480
• Species: Mus musculus
• Alignment Length: 418
• Identity: 106/418 - (25%)
• Similarity: 168/418 - (40%)
• Gaps: 96/418 - (22%)

  Fly    11 SLNATRNEENITSFF----TDEEWLAINGTLPW-------------IVGFFFGVIAITGFFGNLL 58
            |:.|.....|.:|.|    |..:|....|...:             ||.:.|.:  :...|||:|
Mouse    29 SMEAALTGPNASSHFWANYTFSDWQNFVGRRRYGAESQNPTVKALLIVAYSFTI--VFSLFGNVL 91

  Fly    59 VILVVVFNNNMRSTTNLMIVNLAAADLMFVILCIPFTATDYMVYYWPYGRFWCRSVQYLIVVTAF 123
            |..|:..|..|.|.|:|.|||||.||:|..:|..|||...::...|.:|:..|...::....:..
Mouse    92 VCHVIFKNQRMHSATSLFIVNLAVADIMITLLNTPFTLVRFVNSTWVFGKGMCHVSRFAQYCSLH 156

  Fly   124 ASIYTLVLMSIDR-------------------------FL------------------------- 138
            .|..||..:::||                         |:
Mouse   157 VSALTLTAIAVDRHQGLELQKMVRPRGDGGELRSPSVTFVPSSLCPALFTCKRPWDFQESQSLHD 221

  Fly   139 -------AVVHPIRSRMMRTENITLIAIVTLWIVVLVVSVPVAFTHDVVVDYDAKKNITYGMCTF 196
                   .::||::.|:..|:.:..||::  |::....|:|.|....:.. :...::|...:|
Mouse   222 TLFPPLEVIMHPLKPRISITKGVIYIAVI--WVMATFFSLPHAICQKLFT-FKYSEDIVRSLC-- 281

  Fly   197 TTNDFLGP-----RTYQVTFFISSYLLPLMIISGLYMRMIMRLWRQGTGVRMSKES----QRGRK 252
             ..||..|     :...:..||..|||||.|||..|.|:..:||...|...::.|.    :|.:|
Mouse   282 -LPDFPEPADLFWKYLDLATFILLYLLPLFIISVAYARVAKKLWLCNTIGDVTTEQYLALRRKKK 345

  Fly   253 RVTRLVVVVVIAFASLWLPVQLILLLKSLDVIETNTLTKLVIQVTAQTLAYSSSCINPLLYAFLS 317
            ...:::|:||:.||..|.|:...:||.|...|.||.    .:.......|.||:|.||.:|.:|:
Mouse   346 TTVKMLVLVVVLFALCWFPLNCYVLLLSSKAIHTNN----ALYFAFHWFAMSSTCYNPFIYCWLN 406

  Fly   318 ENFRKAFYKAVNCSSRYQNYTSD-LPPP 344
            ||||......::...|......| ||.|
Mouse   407 ENFRVELKALLSMCQRPPKPQEDRLPSP 434

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AstA-R2	NP_524544.1	7tmA_AstA_R_insect	39..324	CDD:320224	93/363 (26%)
		TM helix 1	40..66	CDD:320224	9/25 (36%)
		TM helix 2	73..99	CDD:320224	14/25 (56%)
		TM helix 3	111..141	CDD:320224	7/86 (8%)
		TM helix 4	153..173	CDD:320224	4/19 (21%)
		TM helix 5	204..233	CDD:320224	13/33 (39%)
		TM helix 6	249..279	CDD:320224	10/29 (34%)
		TM helix 7	292..317	CDD:320224	7/24 (29%)
Gpr83	XP_030099918.1	7tmA_GPR83	72..413	CDD:320511	93/352 (26%)
		TM helix 1	73..99	CDD:320511	9/27 (33%)
		TM helix 2	106..131	CDD:320511	14/24 (58%)
		TM helix 3	144..231	CDD:320511	7/86 (8%)
		TM helix 4	242..263	CDD:320511	5/22 (23%)
		TM helix 5	293..322	CDD:320511	12/28 (43%)
		TM helix 6	342..372	CDD:320511	10/29 (34%)
		TM helix 7	381..406	CDD:320511	7/28 (25%)