DRSC/TRiP Functional Genomics Resources

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Protein Alignment AstA-R2 and Ackr3

DIOPT Version :9

Sequence 1:NP_001263042.1 Gene:AstA-R2 / 43393 FlyBaseID:FBgn0039595 Length:357 Species:Drosophila melanogaster
Sequence 2:NP_001258536.1 Gene:Ackr3 / 12778 MGIID:109562 Length:362 Species:Mus musculus


Alignment Length:310 Identity:74/310 - (23%)
Similarity:135/310 - (43%) Gaps:34/310 - (10%)


- Green bases have known domain annotations that are detailed below.


  Fly    36 TLP------WIVGFFFGVIAITGFFGNLLVILVVVFNNNMRSTTNLMIVNLAAADLMFVILCIPF 94
            |:|      :.:.|.:..|.:.|...|.:|:.|.:........|:..|:|||.||| :|::.||.
Mouse    36 TMPNKNVLLYTLSFIYIFIFVIGMIANSVVVWVNIQAKTTGYDTHCYILNLAIADL-WVVITIPV 99

  Fly    95 TATDYMVY-YWPYGRFWCRSVQYLIVVTAFASIYTLVLMSIDRFLAVVHPIRSRMMRTENITLIA 158
            .....:.: .||.|...|:....:..:..|.||:.|..||:||:|::.:...:...:.:.:..:.
Mouse   100 WVVSLVQHNQWPMGELTCKITHLIFSINLFGSIFFLACMSVDRYLSITYFTGTSSYKKKMVRRVV 164

  Fly   159 IVTLWIVVLVVSVPVAFTHDVVVDYDAKKNITYGMCTFTTND----FLGPRTYQVTFFISSYLLP 219
            .:.:|::...||:|..:....|.  .|..|.||....:..:.    .:|.....|   |..:.:|
Mouse   165 CILVWLLAFFVSLPDTYYLKTVT--SASNNETYCRSFYPEHSIKEWLIGMELVSV---ILGFAVP 224

  Fly   220 LMIISGLYMRMIMRLWRQGTGVRMSKESQRGRKRVTRLVVVVVIAFASLWLPVQLILLLKSLDVI 284
            ..||:..|..:...:...|     .:|....||.:...|||.::.    |||...::||....::
Mouse   225 FTIIAIFYFLLARAMSASG-----DQEKHSSRKIIFSYVVVFLVC----WLPYHFVVLLDIFSIL 280

  Fly   285 -------ETNTLTKLVIQVTAQTLAYSSSCINPLLYAFLSENFRKAFYKA 327
                   :...:....:.|| |.|:....|:||:||:|::.|:|....||
Mouse   281 HYIPFTCQLENVLFTALHVT-QCLSLVHCCVNPVLYSFINRNYRYELMKA 329

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
AstA-R2NP_001263042.1 7tm_4 47..>164 CDD:304433 29/117 (25%)
7tm_1 55..313 CDD:278431 62/269 (23%)
Ackr3NP_001258536.1 7tmA_ACKR3_CXCR7 45..326 CDD:320118 70/296 (24%)
TM helix 1 47..71 CDD:320118 6/23 (26%)
TM helix 2 80..101 CDD:320118 10/21 (48%)
TM helix 3 118..140 CDD:320118 5/21 (24%)
TM helix 4 163..179 CDD:320118 3/15 (20%)
TM helix 5 210..233 CDD:320118 6/25 (24%)
TM helix 6 251..273 CDD:320118 8/25 (32%)
TM helix 7 294..319 CDD:320118 10/25 (40%)
C-terminal cytoplasmic tail. /evidence=ECO:0000250 324..362 2/6 (33%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C167837211
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.930

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