Protein Alignment AstA-R2 and Ackr3

DIOPT Version :10

• Sequence 1: NP_524544.1
• Gene: AstA-R2 / 43393
• FlyBaseID: FBgn0039595
• Length: 357
• Species: Drosophila melanogaster
• Sequence 2: NP_031748.2
• Gene: Ackr3 / 12778
• MGIID: 109562
• Length: 362
• Species: Mus musculus
• Alignment Length: 310
• Identity: 74/310 - (23%)
• Similarity: 135/310 - (43%)
• Gaps: 34/310 - (10%)

  Fly    36 TLP------WIVGFFFGVIAITGFFGNLLVILVVVFNNNMRSTTNLMIVNLAAADLMFVILCIPF 94
            |:|      :.:.|.:..|.:.|...|.:|:.|.:........|:..|:|||.||| :|::.||.
Mouse    36 TMPNKNVLLYTLSFIYIFIFVIGMIANSVVVWVNIQAKTTGYDTHCYILNLAIADL-WVVITIPV 99

  Fly    95 TATDYMVY-YWPYGRFWCRSVQYLIVVTAFASIYTLVLMSIDRFLAVVHPIRSRMMRTENITLIA 158
            .....:.: .||.|...|:....:..:..|.||:.|..||:||:|::.:...:...:.:.:..:.
Mouse   100 WVVSLVQHNQWPMGELTCKITHLIFSINLFGSIFFLACMSVDRYLSITYFTGTSSYKKKMVRRVV 164

  Fly   159 IVTLWIVVLVVSVPVAFTHDVVVDYDAKKNITYGMCTFTTND----FLGPRTYQVTFFISSYLLP 219
            .:.:|::...||:|..:....|.  .|..|.||....:..:.    .:|.....|   |..:.:|
Mouse   165 CILVWLLAFFVSLPDTYYLKTVT--SASNNETYCRSFYPEHSIKEWLIGMELVSV---ILGFAVP 224

  Fly   220 LMIISGLYMRMIMRLWRQGTGVRMSKESQRGRKRVTRLVVVVVIAFASLWLPVQLILLLKSLDVI 284
            ..||:..|..:...:...|     .:|....||.:...|||.::.    |||...::||....::
Mouse   225 FTIIAIFYFLLARAMSASG-----DQEKHSSRKIIFSYVVVFLVC----WLPYHFVVLLDIFSIL 280

  Fly   285 -------ETNTLTKLVIQVTAQTLAYSSSCINPLLYAFLSENFRKAFYKA 327
                   :...:....:.|| |.|:....|:||:||:|::.|:|....||
Mouse   281 HYIPFTCQLENVLFTALHVT-QCLSLVHCCVNPVLYSFINRNYRYELMKA 329

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AstA-R2	NP_524544.1	7tmA_AstA_R_insect	39..324	CDD:320224	70/296 (24%)
		TM helix 1	40..66	CDD:320224	6/25 (24%)
		TM helix 2	73..99	CDD:320224	11/25 (44%)
		TM helix 3	111..141	CDD:320224	10/29 (34%)
		TM helix 4	153..173	CDD:320224	3/19 (16%)
		TM helix 5	204..233	CDD:320224	6/28 (21%)
		TM helix 6	249..279	CDD:320224	9/29 (31%)
		TM helix 7	292..317	CDD:320224	10/24 (42%)
Ackr3	NP_031748.2	7tmA_ACKR3_CXCR7	45..326	CDD:320118	70/296 (24%)
		TM helix 1	46..72	CDD:320118	6/25 (24%)
		TM helix 2	79..103	CDD:320118	11/24 (46%)
		TM helix 3	117..147	CDD:320118	10/29 (34%)
		TM helix 4	160..181	CDD:320118	4/20 (20%)
		TM helix 5	209..236	CDD:320118	7/29 (24%)
		TM helix 6	245..275	CDD:320118	10/33 (30%)
		TM helix 7	294..319	CDD:320118	10/25 (40%)
		C-terminal cytoplasmic tail. /evidence=ECO:0000250	324..362		2/6 (33%)