Protein Alignment AstA-R2 and Cckar

DIOPT Version :10

• Sequence 1: NP_524544.1
• Gene: AstA-R2 / 43393
• FlyBaseID: FBgn0039595
• Length: 357
• Species: Drosophila melanogaster
• Sequence 2: NP_033957.1
• Gene: Cckar / 12425
• MGIID: 99478
• Length: 436
• Species: Mus musculus
• Alignment Length: 396
• Identity: 87/396 - (21%)
• Similarity: 168/396 - (42%)
• Gaps: 85/396 - (21%)

  Fly     8 ANISLNATRNEENITSFFTDE-----EWLAINGTLPWIVGFFFGVIAITGFFGNLLVILVVVFNN 67
            :||:.......||.|.|..|:     ||.:....|      .:..|.:....||.|||.|::.|.
Mouse    12 SNITPPCELGLENETLFCLDQPQPSKEWQSAVQIL------LYSFIFLLSVLGNTLVITVLIRNK 70

  Fly    68 NMRSTTNLMIVNLAAADLMFVILCIPFTATDYMVYYWPYGRFWCRSVQYLIVVTAFASIYTLVLM 132
            .||:.||:.:::||.:|||..:.|:||.....::..:.:|...|::..|.:..:...|.:.||.:
Mouse    71 RMRTVTNIFLLSLAVSDLMLCLFCMPFNLIPNLLKDFIFGSAVCKTTTYFMGTSVSVSTFNLVAI 135

  Fly   133 SIDRFLAVVHPIRSRMMRTENITLIAIVTLWIVVLVVSVPVAFTHDVVVDYDAKKNITYGMCTFT 197
            |::|:.|:..|::||:.:|::..|..|...|.:...:..|... :..:|.:....|.|..||.|.
Mouse   136 SLERYGAICRPLQSRVWQTKSHALKVIAATWCLSFTIMTPYPI-YSNLVPFTKNNNQTANMCRFL 199

  Fly   198 TNDFLGPRTYQVTFFISSYLLP--LMIIS------------------------------------ 224
            .......:::|....:..:|:|  :|:::
Mouse   200 LPSDAMQQSWQTFLLLILFLIPGVVMVVAYGLISLELYQGIKFDASQKKSAKEKRLSSGGGGGGG 264

  Fly   225 ----------GLYMRM--------IMRLWRQGTGVRMSKESQRG-------RKRVTRLVVVVVIA 264
                      |.|::.        :.:|....:|.|:::....|       :|||.|:::|:|:.
Mouse   265 SSSSRYEDSDGCYLQKSRPPRKLELQQLSTSSSGGRINRIRSSGSAANLIAKKRVIRMLIVIVVL 329

  Fly   265 FASLWLPVQLILLLKSLDVIE-----TNTLTKLVIQVTAQTLAYSSSCINPLLYAFLSENFRKAF 324
            |...|:|:......::.|.:.     :.|....::     .|:|:|||:||::|.|:::.||..|
Mouse   330 FFLCWMPIFSANAWRAYDTVSAEKHLSGTPISFIL-----LLSYTSSCVNPIIYCFMNKRFRLGF 389

  Fly   325 YKAVNC 330
            .....|
Mouse   390 MATFPC 395

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AstA-R2	NP_524544.1	7tmA_AstA_R_insect	39..324	CDD:320224	75/352 (21%)
		TM helix 1	40..66	CDD:320224	7/25 (28%)
		TM helix 2	73..99	CDD:320224	10/25 (40%)
		TM helix 3	111..141	CDD:320224	8/29 (28%)
		TM helix 4	153..173	CDD:320224	3/19 (16%)
		TM helix 5	204..233	CDD:320224	6/84 (7%)
		TM helix 6	249..279	CDD:320224	10/36 (28%)
		TM helix 7	292..317	CDD:320224	9/24 (38%)
Cckar	NP_033957.1	CholecysA-Rec_N	1..47	CDD:462713	10/40 (25%)
		7tm_GPCRs	42..389	CDD:475119	76/358 (21%)
		TM helix 1	44..68	CDD:410628	8/29 (28%)
		TM helix 2	77..99	CDD:410628	9/21 (43%)
		TM helix 3	115..137	CDD:410628	4/21 (19%)
		TM helix 4	160..176	CDD:410628	2/15 (13%)
		TM helix 5	207..230	CDD:410628	4/22 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	252..280		2/27 (7%)
		TM helix 6	320..342	CDD:410628	6/21 (29%)
		TM helix 7	357..382	CDD:410628	10/29 (34%)