Protein Alignment AstA-R2 and CCR1

DIOPT Version :10

• Sequence 1: NP_524544.1
• Gene: AstA-R2 / 43393
• FlyBaseID: FBgn0039595
• Length: 357
• Species: Drosophila melanogaster
• Sequence 2: NP_001286.1
• Gene: CCR1 / 1230
• HGNCID: 1602
• Length: 355
• Species: Homo sapiens
• Alignment Length: 297
• Identity: 75/297 - (25%)
• Similarity: 150/297 - (50%)
• Gaps: 30/297 - (10%)

  Fly    45 FGVIAITGFFGNLLVILVVVFNNNMRSTTNLMIVNLAAADLMFVILCIPFTATDYMVYYWPYGRF 109
            :.::.:.|..||:||:||:|....:::.|::.::|||.:||:| :..:||.....:...|.:|..
Human    41 YSLVFVIGLVGNILVVLVLVQYKRLKNMTSIYLLNLAISDLLF-LFTLPFWIDYKLKDDWVFGDA 104

  Fly   110 WCRSVQYLIVVTAFASIYTLVLMSIDRFLAVVHPIRSRMMRTENITLIAIVTLWIVVLVVSVPVA 174
            .|:.:........::.|:.::|::|||:||:||.:.:...||....:|..:.:|.:.::.|:|..
Human   105 MCKILSGFYYTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIIIWALAILASMPGL 169

  Fly   175 FTHDVVVDYDAKKNITYGMCT--FTTNDFLGPRTYQ-VTFFISSYLLPLMIISGLYMRMIMRLWR 236
            :......::      |:..|:  |........:.:| :...:...:|||:::...|..:|..|.|
Human   170 YFSKTQWEF------THHTCSLHFPHESLREWKLFQALKLNLFGLVLPLLVMIICYTGIIKILLR 228

  Fly   237 QGTGVRMSKESQRGRKRVTRLVVVVVIAFASLWLPVQLILLLKSL-DVIETNTLTK-----LVIQ 295
            :         ....:.:..||:.|::|.|...|.|..|.:|:... |.:.|:...:     |.:|
Human   229 R---------PNEKKSKAVRLIFVIMIIFFLFWTPYNLTILISVFQDFLFTHECEQSRHLDLAVQ 284

  Fly   296 VTAQTLAYSSSCINPLLYAFLSENFRK----AFYKAV 328
            || :.:||:..|:||::|||:.|.|||    .|::.|
Human   285 VT-EVIAYTHCCVNPVIYAFVGERFRKYLRQLFHRRV 320

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AstA-R2	NP_524544.1	7tmA_AstA_R_insect	39..324	CDD:320224	73/291 (25%)
		TM helix 1	40..66	CDD:320224	8/20 (40%)
		TM helix 2	73..99	CDD:320224	9/25 (36%)
		TM helix 3	111..141	CDD:320224	8/29 (28%)
		TM helix 4	153..173	CDD:320224	3/19 (16%)
		TM helix 5	204..233	CDD:320224	6/29 (21%)
		TM helix 6	249..279	CDD:320224	9/29 (31%)
		TM helix 7	292..317	CDD:320224	12/24 (50%)
CCR1	NP_001286.1	7tmA_CCR1	35..312	CDD:320311	73/287 (25%)
		TM helix 1	35..62	CDD:320311	8/20 (40%)
		TM helix 2	69..94	CDD:320311	9/25 (36%)
		TM helix 3	106..136	CDD:320311	8/29 (28%)
		TM helix 4	148..170	CDD:320311	4/21 (19%)
		TM helix 5	196..225	CDD:320311	6/28 (21%)
		TM helix 6	232..262	CDD:320311	9/29 (31%)
		TM helix 7	280..305	CDD:320311	12/25 (48%)