Protein Alignment AstA-R2 and Brs3

DIOPT Version :10

• Sequence 1: NP_524544.1
• Gene: AstA-R2 / 43393
• FlyBaseID: FBgn0039595
• Length: 357
• Species: Drosophila melanogaster
• Sequence 2: NP_033896.2
• Gene: Brs3 / 12209
• MGIID: 1100501
• Length: 399
• Species: Mus musculus
• Alignment Length: 371
• Identity: 98/371 - (26%)
• Similarity: 182/371 - (49%)
• Gaps: 22/371 - (5%)

  Fly     3 NTTMLANISLNATRNEENITSFFTDEE-WLAINGTLPWIVGF------FFGVIAITGFFGNLLVI 60
            |.|:::  ..|.|....::.|..|..: |...|.  |.|...      :.|:|:: |..||.::|
Mouse    10 NQTLIS--ITNDTETSSSVVSNDTTHKGWTGDNS--PGIEALCAIYITYAGIISV-GILGNAILI 69

  Fly    61 LVVVFNNNMRSTTNLMIVNLAAADLMFVILCIPFTATDYMVYYWPYGRFWCRSVQYLIVVTAFAS 125
            .|.....:|::..|:.|.:||..||:.::.|:|..||.|:...|.:|:..|:.:.::.:.:...|
Mouse    70 KVFFKTKSMQTVPNIFITSLAFGDLLLLLTCVPVDATHYLAEGWLFGKVGCKVLSFIRLTSVGVS 134

  Fly   126 IYTLVLMSIDRFLAVVHPIRSRMMRTENITLIAIVTLWIVVLVVSVPVAFTHDVVVDYDAKKNIT 190
            ::||.::|.||:.|||.|:..:.......|......:|||.::.::|.|...:|....|..:|:|
Mouse   135 VFTLTILSADRYKAVVKPLERQPPNAILKTCAKAGGIWIVSMIFALPEAIFSNVYTFQDPNRNVT 199

  Fly   191 YGMC-TFTTNDFLGPRTYQVTFFISSYLLPLMIISGLYMRMIMRLWRQGTGVRMSKESQ-----R 249
            :..| ::..::.|....:.:..|:..|::||.|||..|..:...|::....:...::|.     .
Mouse   200 FESCNSYPISERLLQEIHSLLCFLVFYIIPLSIISVYYSLIARTLYKSTLNIPTEEQSHARKQIE 264

  Fly   250 GRKRVTRLVVVVVIAFASLWLPVQLILLLKSL--DVIETNTLTKLVIQVTAQTLAYSSSCINPLL 312
            .|||:.:.|:|:|..||..|||..|:.|..|.  :....::....||.:.::.||:|:||:||..
Mouse   265 SRKRIAKTVLVLVALFALCWLPNHLLYLYHSFTYESYANHSDVPFVIIIFSRVLAFSNSCVNPFA 329

  Fly   313 YAFLSENFRKAFYKAVNC--SSRYQNYTSDLPPPRKTSCARTSTTG 356
            ..:||:.|::.|...:.|  :.:.:....|:|....|...|...||
Mouse   330 LYWLSKTFQQHFKAQLCCLKAEQPEPPLGDIPLNNLTVMGRVPATG 375

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AstA-R2	NP_524544.1	7tmA_AstA_R_insect	39..324	CDD:320224	81/298 (27%)
		TM helix 1	40..66	CDD:320224	8/31 (26%)
		TM helix 2	73..99	CDD:320224	10/25 (40%)
		TM helix 3	111..141	CDD:320224	8/29 (28%)
		TM helix 4	153..173	CDD:320224	4/19 (21%)
		TM helix 5	204..233	CDD:320224	8/28 (29%)
		TM helix 6	249..279	CDD:320224	13/29 (45%)
		TM helix 7	292..317	CDD:320224	9/24 (38%)
Brs3	NP_033896.2	7tm_GPCRs	48..341	CDD:475119	80/293 (27%)
		TM helix 1	50..74	CDD:320251	7/24 (29%)
		TM helix 2	83..105	CDD:320251	8/21 (38%)
		TM helix 3	121..143	CDD:320251	3/21 (14%)
		TM helix 4	166..182	CDD:320251	3/15 (20%)
		TM helix 5	215..238	CDD:320251	7/22 (32%)
		TM helix 6	270..292	CDD:320251	9/21 (43%)
		TM helix 7	309..334	CDD:320251	9/24 (38%)