Protein Alignment AstA-R2 and CXCR6

DIOPT Version :10

• Sequence 1: NP_524544.1
• Gene: AstA-R2 / 43393
• FlyBaseID: FBgn0039595
• Length: 357
• Species: Drosophila melanogaster
• Sequence 2: NP_006555.1
• Gene: CXCR6 / 10663
• HGNCID: 16647
• Length: 342
• Species: Homo sapiens
• Alignment Length: 333
• Identity: 87/333 - (26%)
• Similarity: 161/333 - (48%)
• Gaps: 58/333 - (17%)

  Fly    11 SLNATRNEENITSFFTDEEWLAINGT-LPWIVGFFFGVIAITGFFGNLLVILVVVFNNNMRSTTN 74
            |.|.:..||:       :::|..:.. ||.:    :.|:.:.|..||.||:::.:|.:.::|.|:
Human    14 SFNDSSQEEH-------QDFLQFSKVFLPCM----YLVVFVCGLVGNSLVLVISIFYHKLQSLTD 67

  Fly    75 LMIVNLAAADLMFVILC-IPFTATDYM-VYYWPYGRFWCRSVQYLIVVTAFASIYTLVLMSIDRF 137
            :.:|||..|||:||  | :||.|  |. ::.|.:|:..|:|:..:..:..:.|:..|..:::|||
Human    68 VFLVNLPLADLVFV--CTLPFWA--YAGIHEWVFGQVMCKSLLGIYTINFYTSMLILTCITVDRF 128

  Fly   138 LAVVHPIRSRMMRTENIT--LIAIVTLWIVVLVVSVPVAFTHDVVVDYDAKKNITYG-------- 192
            :.||...::...:.:.:|  .:..:.:|::.|:||:|               .|.||
Human   129 IVVVKATKAYNQQAKRMTWGKVTSLLIWVISLLVSLP---------------QIIYGNVFNLDKL 178

  Fly   193 MCTFTTNDFLGPRTYQVTFFISSYLLPLMIISGLYMRMIMRLWRQGTGVRMSKESQRGRKRVTRL 257
            :|.:  :|.........|.....:.|||:.:...|..:|..|...| |.:        :.|..::
Human   179 ICGY--HDEAISTVVLATQMTLGFFLPLLTMIVCYSVIIKTLLHAG-GFQ--------KHRSLKI 232

  Fly   258 VVVVVIAFASLWLPVQLILLLKSLDVIETNTLTKL--VIQVTAQTLAYSSSCINPLLYAFLSENF 320
            :.:|:..|....:|..|:..::|.. .|...:|..  .|.|| :.:||..:|:||:||||:|..|
Human   233 IFLVMAVFLLTQMPFNLMKFIRSTH-WEYYAMTSFHYTIMVT-EAIAYLRACLNPVLYAFVSLKF 295

  Fly   321 RKAFYKAV 328
            ||.|:|.|
Human   296 RKNFWKLV 303

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AstA-R2	NP_524544.1	7tmA_AstA_R_insect	39..324	CDD:320224	77/298 (26%)
		TM helix 1	40..66	CDD:320224	6/25 (24%)
		TM helix 2	73..99	CDD:320224	13/26 (50%)
		TM helix 3	111..141	CDD:320224	7/29 (24%)
		TM helix 4	153..173	CDD:320224	5/21 (24%)
		TM helix 5	204..233	CDD:320224	6/28 (21%)
		TM helix 6	249..279	CDD:320224	5/29 (17%)
		TM helix 7	292..317	CDD:320224	12/26 (46%)
CXCR6	NP_006555.1	7tmA_CXCR6	32..299	CDD:320301	79/302 (26%)
		TM helix 1	32..59	CDD:320301	8/30 (27%)
		TM helix 2	66..91	CDD:320301	14/28 (50%)
		TM helix 3	102..132	CDD:320301	7/29 (24%)
		TM helix 4	146..168	CDD:320301	6/36 (17%)
		TM helix 5	188..217	CDD:320301	6/28 (21%)
		TM helix 6	224..254	CDD:320301	5/37 (14%)
		TM helix 7	267..292	CDD:320301	12/25 (48%)