Protein Alignment AstA-R2 and ghsr

DIOPT Version :10

• Sequence 1: NP_524544.1
• Gene: AstA-R2 / 43393
• FlyBaseID: FBgn0039595
• Length: 357
• Species: Drosophila melanogaster
• Sequence 2: XP_002931618.1
• Gene: ghsr / 100497774
• XenbaseID: XB-GENE-484475
• Length: 359
• Species: Xenopus tropicalis
• Alignment Length: 323
• Identity: 85/323 - (26%)
• Similarity: 151/323 - (46%)
• Gaps: 51/323 - (15%)

  Fly    47 VIAITGFFGNLLVILVVVFNNNMRSTTNLMIVNLAAADLMFVILCIPFTATDYMVYY-WPYGRFW 110
            ::.|.|..||::.:|||....:||:||||.:.::|.:||: :.||:|........|. |.:|...
 Frog    45 LLFIIGISGNVMTMLVVSKYKDMRTTTNLYLSSMAFSDLL-IFLCMPLDLYRLWQYRPWNFGSSL 108

  Fly   111 CRSVQYLIVVTAFASIYTLVLMSIDRFLAVVHPIRSRMMRTENITLIAIVTLWIVVLVVSVPVAF 175
            |:..|::.....:::|..:..:|::|:.|:..|::::::.|:....:.|..||.|..|.:.|:..
 Frog   109 CKLFQFVSECCTYSTILNITALSVERYFAICFPLKAKVVITKGRVKLVISVLWAVSFVSAGPIFV 173

  Fly   176 THDVVVDYDAKKN-------------ITYGMCTFTTNDFLGPRTYQVTFFISSYLLPLMIISGLY 227
            .  |.|:::...|             |..|:.|...      .|..:.||     ||:..::.||
 Frog   174 L--VGVEHENGTNPLDTNECKATEYAIKSGLLTIMV------WTSSIFFF-----LPVFCLTVLY 225

  Fly   228 MRMIMRLWRQ-------GTGVRMSKESQRGRKRVTRLVVVVVIAFASLWLP--VQLILLLKSLDV 283
            ..:..:|||:       .|.:|     .:..|:..:::.|||.||...|||  |...|..||
 Frog   226 TLIGRKLWRRKRETIGPHTSIR-----DKHNKQTVKMLAVVVFAFILCWLPFHVARYLFSKS--- 282

  Fly   284 IETNTLTKLVI----QVTAQTLAYSSSCINPLLYAFLSENFRKAFYKAVNCS--SRYQNYTSD 340
            .|..:|...:|    .:.:..|.|.|:.|||:||..:|:.:|.|..:.....  ||...||::
 Frog   283 FEAGSLEIALISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAACRLFRLKQVSRKATYTTN 345

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AstA-R2	NP_524544.1	7tmA_AstA_R_insect	39..324	CDD:320224	80/303 (26%)
		TM helix 1	40..66	CDD:320224	7/18 (39%)
		TM helix 2	73..99	CDD:320224	9/25 (36%)
		TM helix 3	111..141	CDD:320224	6/29 (21%)
		TM helix 4	153..173	CDD:320224	5/19 (26%)
		TM helix 5	204..233	CDD:320224	7/28 (25%)
		TM helix 6	249..279	CDD:320224	11/31 (35%)
		TM helix 7	292..317	CDD:320224	9/28 (32%)
ghsr	XP_002931618.1	7tmA_GHSR	37..327	CDD:320259	80/303 (26%)
		TM helix 1	37..64	CDD:320259	7/18 (39%)
		TM helix 2	71..96	CDD:320259	9/25 (36%)
		TM helix 3	109..139	CDD:320259	6/29 (21%)
		TM helix 4	151..173	CDD:320259	6/21 (29%)
		TM helix 5	202..231	CDD:320259	8/39 (21%)
		TM helix 6	249..279	CDD:320259	10/29 (34%)
		TM helix 7	295..320	CDD:320259	8/24 (33%)