Protein Alignment AstA-R2 and LOC100489992

DIOPT Version :10

• Sequence 1: NP_524544.1
• Gene: AstA-R2 / 43393
• FlyBaseID: FBgn0039595
• Length: 357
• Species: Drosophila melanogaster
• Sequence 2: XP_002941889.1
• Gene: LOC100489992 / 100489992
• XenbaseID: XB-GENE-29079991
• Length: 414
• Species: Xenopus tropicalis
• Alignment Length: 367
• Identity: 103/367 - (28%)
• Similarity: 181/367 - (49%)
• Gaps: 47/367 - (12%)

  Fly     5 TMLANISLNATRNEENITSF-FTDE---EWL-----------AINGTLPWIVGFFFGVIAITGFF 54
            |:||...:      .|.||| |||.   ||.           |...|:..::...:.||.:...|
 Frog    30 TLLAKFQI------MNRTSFNFTDSRIGEWERFAELAKYESDAQKPTVQALLIVAYSVIIVMSLF 88

  Fly    55 GNLLVILVVVFNNNMRSTTNLMIVNLAAADLMFVILCIPFTATDYMVYYWPYGRFWCRSVQYLIV 119
            ||:||..||:.|..|.|.|:|.|||||.:|:|..:|..|||...::...|.:|:..|...:::..
 Frog    89 GNMLVCHVVMKNKRMHSATSLFIVNLAVSDIMITLLNTPFTLVRFVNSTWVFGKEMCHISRFVQY 153

  Fly   120 VTAFASIYTLVLMSIDRFLAVVHPIRSRMMRTENITLIAIVTLWIVVLVVSVPVAFTHDVVVDYD 184
            .:...|..||..:::||...:::|::.||..::.:..|:.:  |::....|:|.|. :..:..|:
 Frog   154 CSLHVSTLTLTAIALDRHQVILNPLKPRMSLSKGVLCISFI--WVMATCFSLPHAI-YQKLFRYN 215

  Fly   185 AKKNITYGMCTFTTNDFLGP-----RTYQVTFFISSYLLPLMIISGLYMRMIMRLWRQGTGVRMS 244
            .::|....:|   ..||..|     :...::.|:..|||||:||:..|.|:..:||.:.....::
 Frog   216 YRENKVRSLC---IPDFPEPSDLFWKYLDLSTFLLLYLLPLLIITIAYSRLAKKLWMRNAIGDIT 277

  Fly   245 KES----QRGRKRVTRLVVVVVIAFASLWLPVQ-LILLLKSLDVIETNTLTKLVIQVTAQTLAYS 304
            .|.    ::.:|:..:::|:||:.||..|.|:. .::|:.||.:     .||..:.......|.|
 Frog   278 TEQYITHRKNKKKSIKMLVLVVVVFAVCWFPLNCYVVLISSLGI-----KTKNALYFALHWFAMS 337

  Fly   305 SSCINPLLYAFLSENFRKAFYKAVNCSSRY---QNYTSDLPP 343
            |:|.||.:|.:|:|:||......::...|.   |::.  |||
 Frog   338 STCYNPFIYCWLNESFRLELKSLLSMCQRIPAAQDHA--LPP 377

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AstA-R2	NP_524544.1	7tmA_AstA_R_insect	39..324	CDD:320224	84/294 (29%)
		TM helix 1	40..66	CDD:320224	9/25 (36%)
		TM helix 2	73..99	CDD:320224	13/25 (52%)
		TM helix 3	111..141	CDD:320224	6/29 (21%)
		TM helix 4	153..173	CDD:320224	3/19 (16%)
		TM helix 5	204..233	CDD:320224	11/33 (33%)
		TM helix 6	249..279	CDD:320224	9/30 (30%)
		TM helix 7	292..317	CDD:320224	7/24 (29%)
LOC100489992	XP_002941889.1	7tmA_GPR83	73..357	CDD:320511	84/294 (29%)
		TM helix 1	74..100	CDD:320511	9/25 (36%)
		TM helix 2	107..132	CDD:320511	13/24 (54%)
		TM helix 3	145..175	CDD:320511	6/29 (21%)
		TM helix 4	186..207	CDD:320511	4/22 (18%)
		TM helix 5	237..266	CDD:320511	10/28 (36%)
		TM helix 6	286..316	CDD:320511	8/29 (28%)
		TM helix 7	325..350	CDD:320511	7/24 (29%)