Protein Alignment AstA-R2 and tacr3

DIOPT Version :10

• Sequence 1: NP_524544.1
• Gene: AstA-R2 / 43393
• FlyBaseID: FBgn0039595
• Length: 357
• Species: Drosophila melanogaster
• Sequence 2: XP_002934808.1
• Gene: tacr3 / 100486525
• XenbaseID: XB-GENE-985728
• Length: 431
• Species: Xenopus tropicalis
• Alignment Length: 307
• Identity: 83/307 - (27%)
• Similarity: 149/307 - (48%)
• Gaps: 36/307 - (11%)

  Fly    38 PWIVGFF---FGVIAITGFFGNLLVILVVVFNNNMRSTTNLMIVNLAAADLMFVILCIPFTATDY 99
            ||.:..:   :|.:.....|||::||.:::.:..||:.||..:||||.:|....    .|.....
 Frog    46 PWRIALWSLAYGSMVAVAVFGNIIVIWIILAHKRMRTVTNYFLVNLAFSDASMA----AFNTLVN 106

  Fly   100 MVY----YWPYGRFWCRSVQYLIVVTAFASIYTLVLMSIDRFLAVVHPIRSRMMRTENITLIAIV 160
            .:|    .|.:|..:||...:..:.:.|||||::..:::||::|::.|::.|:..|.  |.:.|.
 Frog   107 FIYALHNEWYFGEAYCRFHNFFPITSIFASIYSMSAIAVDRYMAIIDPLKPRLSATS--TKVVIG 169

  Fly   161 TLWIVVLVVSVPVAFTHDVVVDYDAKKNITYGMCTFTTNDFLGPRTYQVTFFISSYLLPLMIISG 225
            ::||..::::.|......:.|    .:..|..|..:...|  ...|||....:..|:|||:::..
 Frog   170 SIWIFAILLAFPQCLYSKIRV----TRTRTLCMLVWPGKD--ERLTYQFILVLLVYVLPLIVMGV 228

  Fly   226 LYMRMIMRLWR---QGTGVRMSKESQRGRKRVTRLVVVVVIAFASLWLPVQLILLLKSLDVIETN 287
            .|..:.:.||.   .|.......|..|.:::|.::::|||:.||..|||..:..|..:||:
 Frog   229 TYTIVGITLWGGEIPGDTSDKYHEQLRAKRKVVKMMIVVVVTFAICWLPYHIFFLADALDI---- 289

  Fly   288 TLTKL-------VIQVTAQTLAYSSSCINPLLYAFLSENFRKAFYKA 327
               ||       .|.:....||.||:..||::|..|::.||..|.:|
 Frog   290 ---KLDRWKYIQQIYLAIFWLAMSSTMYNPIIYCCLNKRFRAGFKRA 333

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AstA-R2	NP_524544.1	7tmA_AstA_R_insect	39..324	CDD:320224	80/301 (27%)
		TM helix 1	40..66	CDD:320224	6/28 (21%)
		TM helix 2	73..99	CDD:320224	8/25 (32%)
		TM helix 3	111..141	CDD:320224	10/29 (34%)
		TM helix 4	153..173	CDD:320224	4/19 (21%)
		TM helix 5	204..233	CDD:320224	8/28 (29%)
		TM helix 6	249..279	CDD:320224	11/29 (38%)
		TM helix 7	292..317	CDD:320224	9/31 (29%)
tacr3	XP_002934808.1	7tm_GPCRs	50..330	CDD:475119	79/298 (27%)
		TM helix 1	52..76	CDD:320669	6/23 (26%)
		TM helix 2	85..107	CDD:320669	7/25 (28%)
		TM helix 3	123..145	CDD:320669	6/21 (29%)
		TM helix 4	166..182	CDD:320669	3/15 (20%)
		TM helix 5	208..231	CDD:320669	7/22 (32%)
		TM helix 6	261..283	CDD:320669	8/21 (38%)
		TM helix 7	298..323	CDD:320669	8/24 (33%)