Protein Alignment AstA-R2 and sstr2a

DIOPT Version :10

• Sequence 1: NP_524544.1
• Gene: AstA-R2 / 43393
• FlyBaseID: FBgn0039595
• Length: 357
• Species: Drosophila melanogaster
• Sequence 2: XP_005170178.1
• Gene: sstr2a / 100333578
• ZFINID: ZDB-GENE-140130-1
• Length: 379
• Species: Danio rerio
• Alignment Length: 354
• Identity: 117/354 - (33%)
• Similarity: 184/354 - (51%)
• Gaps: 37/354 - (10%)

  Fly     1 MENTTMLANISLNATRNEENITSFFTDE------EWLAINGTLPW-------IVGFFFGVIAITG 52
            |:..|.:.|.:|:......| .|||...      |:...|||.|.       ::.|.:.|:...|
Zfish     1 MDTWTFMPNSNLSLPDRLVN-DSFFPGNESDFGLEFYPPNGTHPGFDHTSSVVITFVYFVVCAVG 64

  Fly    53 FFGNLLVILVVVFNNNMRSTTNLMIVNLAAADLMFVILCIPFTATDYMVYYWPYGRFWCRSVQYL 117
            ..||.|||.|::....|::.||:.|:|||.||:: .:|.:||.|....:.:||:|...||.|..:
Zfish    65 LCGNALVIYVILRYAKMKTVTNIYILNLAVADVL-CMLSLPFIAIQLSLLHWPFGSAICRVVLTV 128

  Fly   118 IVVTAFASIYTLVLMSIDRFLAVVHPIRSRMMRTENITLIAIVTLWIVVLVVSVPVAFTHDVVVD 182
            ..:..|.||:.|.:||.||:|||||||:|...|...:.....:.:|.|.|:|::|:.....|
Zfish   129 DSMNQFTSIFFLTVMSFDRYLAVVHPIKSTKWRKPRMAKTISLGMWSVALLVNLPIMIYSGV--- 190

  Fly   183 YDAKKNITYGMCTFTTNDFLGP---RTYQVTF----FISSYLLPLMIISGLYMRMIMRLWRQGTG 240
             :|||| ....||     .|.|   .||...|    |...:.|||::||..|:.:::::  :.:|
Zfish   191 -NAKKN-EARTCT-----MLWPEPQNTYYTAFIFYTFFLGFFLPLIVISMCYLLIVIKV--KSSG 246

  Fly   241 VRM-SKESQRGRKRVTRLVVVVVIAFASLWLPVQLILLLKSLDVIETNTLTKLVIQVTAQTLAYS 304
            :|: |.:.:|..::|||:|.:||:.|...|||..:..:......:.|..:.|....... .|.|:
Zfish   247 MRVGSTKRKRSERKVTRMVSIVVVVFVLCWLPFYVFNVTSVTGTVPTTPVLKSTFDFVV-VLGYA 310

  Fly   305 SSCINPLLYAFLSENFRKAFYKAVNCSSR 333
            :||.||:||||||:||:|:| :.|.|..|
Zfish   311 NSCANPILYAFLSDNFKKSF-QNVLCLKR 338

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AstA-R2	NP_524544.1	7tmA_AstA_R_insect	39..324	CDD:320224	100/299 (33%)
		TM helix 1	40..66	CDD:320224	9/25 (36%)
		TM helix 2	73..99	CDD:320224	12/25 (48%)
		TM helix 3	111..141	CDD:320224	13/29 (45%)
		TM helix 4	153..173	CDD:320224	4/19 (21%)
		TM helix 5	204..233	CDD:320224	11/35 (31%)
		TM helix 6	249..279	CDD:320224	11/29 (38%)
		TM helix 7	292..317	CDD:320224	10/24 (42%)
sstr2a	XP_005170178.1	7tm_GPCRs	51..330	CDD:475119	100/292 (34%)
		TM helix 1	53..77	CDD:320637	9/23 (39%)
		TM helix 2	86..107	CDD:320637	10/21 (48%)
		TM helix 3	123..145	CDD:320637	7/21 (33%)
		TM helix 4	168..184	CDD:320637	4/15 (27%)
		TM helix 5	213..236	CDD:320637	7/22 (32%)
		TM helix 6	262..284	CDD:320637	9/21 (43%)
		TM helix 7	298..323	CDD:320637	11/25 (44%)