Protein Alignment AstA-R2 and tacr1

DIOPT Version :10

• Sequence 1: NP_524544.1
• Gene: AstA-R2 / 43393
• FlyBaseID: FBgn0039595
• Length: 357
• Species: Drosophila melanogaster
• Sequence 2: NP_001106489.1
• Gene: tacr1 / 100127678
• XenbaseID: XB-GENE-5835469
• Length: 407
• Species: Xenopus tropicalis
• Alignment Length: 339
• Identity: 92/339 - (27%)
• Similarity: 160/339 - (47%)
• Gaps: 48/339 - (14%)

  Fly     9 NISL------NAT-RNEENITSFFTDEEW-LAINGTLPWIVGFFFGVIAITGFFGNLLVILVVVF 65
            |||:      |:| .||..|.:.|....| :|:     |.:.  :.:|.|....||::|:.:::.
 Frog     2 NISMQNSSICNSTGGNETCIVNPFLQPAWQIAL-----WSIA--YSIIVIVSVVGNIIVMWIILA 59

  Fly    66 NNNMRSTTNLMIVNLAAADLMFVIL--CIPFTATDYMVY-YWPYGRFWCRSVQYLIVVTAFASIY 127
            :..||:.||..:||||.|:......  .|.||   |.:: :|.||..:|:...:..:...|:|||
 Frog    60 HKRMRTVTNYFLVNLAFAEASMSAFNTVINFT---YAIHNHWYYGLIYCKFHNFFPISAVFSSIY 121

  Fly   128 TLVLMSIDRFLAVVHPIRSRMMRTENITLIAIVTLWIVVLVVSVPVAF------THDVVV---DY 183
            ::..:::||::|::||::.|:..|  .|.|.|..:|.....::.|..:      |.|.||   ::
 Frog   122 SMTAIALDRYMAIIHPLKPRLSAT--ATRIVIAVIWGFAFALAFPQGYFATVEPTPDRVVCYMEW 184

  Fly   184 DAKKNITYGMCTFTTNDFLGPRTYQVTFFISSYLLPLMIISGLYMRMIMRLWRQ---GTGVRMSK 245
            ...:|..:            .:.|||..|...|.|||::|...|..:.|.||..   |.......
 Frog   185 PESENRKF------------EKVYQVLLFGLIYFLPLLVIGCSYTFIGMTLWASEIPGDSSDRYH 237

  Fly   246 ESQRGRKRVTRLVVVVVIAFASLWLPVQLILLLKSLDVIETNTLTKLVIQVTAQTLAYSSSCINP 310
            |....:::|.::::|||..||..|||..:..||:.....|:....: .:.:....|..||:..||
 Frog   238 EQVVAKRKVVKMMIVVVCTFAICWLPYHIYFLLQLFLPDESQKFYQ-QLYLGIMWLGMSSTMYNP 301

  Fly   311 LLYAFLSENFRKAF 324
            ::|..|::.||..|
 Frog   302 IIYCCLNDRFRIGF 315

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AstA-R2	NP_524544.1	7tmA_AstA_R_insect	39..324	CDD:320224	80/299 (27%)
		TM helix 1	40..66	CDD:320224	5/25 (20%)
		TM helix 2	73..99	CDD:320224	10/27 (37%)
		TM helix 3	111..141	CDD:320224	8/29 (28%)
		TM helix 4	153..173	CDD:320224	4/19 (21%)
		TM helix 5	204..233	CDD:320224	10/28 (36%)
		TM helix 6	249..279	CDD:320224	10/29 (34%)
		TM helix 7	292..317	CDD:320224	6/24 (25%)
tacr1	NP_001106489.1	7tmA_NK1R	33..315	CDD:320668	81/306 (26%)
		TM helix 1	34..60	CDD:320668	6/32 (19%)
		TM helix 2	67..93	CDD:320668	10/28 (36%)
		TM helix 3	105..135	CDD:320668	8/29 (28%)
		TM helix 4	146..167	CDD:320668	5/20 (25%)
		TM helix 5	193..222	CDD:320668	10/28 (36%)
		TM helix 6	241..271	CDD:320668	10/29 (34%)
		TM helix 7	283..308	CDD:320668	6/25 (24%)