DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment AstA-R2 and XB5962511

DIOPT Version :9

Sequence 1:	NP_001263042.1	Gene:	AstA-R2 / 43393	FlyBaseID:	FBgn0039595	Length:	357	Species:	Drosophila melanogaster
Sequence 2:	NP_001096443.1	Gene:	XB5962511 / 100125055	XenbaseID:	XB-GENE-5962512	Length:	369	Species:	Xenopus tropicalis

Alignment Length:	314	Identity:	99/314 - (31%)
Similarity:	172/314 - (54%)	Gaps:	30/314 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    38 PW-------------IVGFFFGVIAITGFFGNLLVILVVVFNNNMR--STTNLMIVNLAAADLMF 87
            ||             :|...|.:|.:.|..||.|| |.|:..:..|  :||||.|:||:.||:.|
Frog    13 PWNSSDLSLFSPASIVVPVIFSLIFLLGTVGNSLV-LAVLLRSGQRTHNTTNLFILNLSVADVSF 76

  Fly    88 VILCIPFTATDYMVYYWPYGRFWCRSVQYLIVVTAFASIYTLVLMSIDRFLAVVHPIRSRMMRTE 152
            :|.|:||.||.|.:..|.:|.|.|::|.:.|.:|.:||.:||..:|:||:||:.:|:|||.:||.
Frog    77 IIFCVPFQATIYSLEDWVFGAFMCKAVHFFIYLTMYASSFTLAAVSVDRYLAIRYPLRSRELRTP 141

  Fly   153 NITLIAIVTLWIVVLVVSVPVAFTHDVVVDYDAKKNITYGMCTFTTNDFLGPRTYQVT---FFIS 214
            ...:..:..:|.:.:|.:.|....:| ::||::......|.         ..||.::.   .||.
Frog   142 CNAIATMAIIWGLSVVFAGPYLSYYD-LMDYESSHICMPGW---------KERTRKIMDTGTFIV 196

  Fly   215 SYLLPLMIISGLYMRMIMRLWRQGTGVRMSKESQRGRKRVTRLVVVVVIAFASLWLPVQLILLLK 279
            .|::|::|:|..|.|.|..||.....:....||::.:::||:::::|.:.|...|||..::::..
Frog   197 GYVIPVLIVSLSYTRTIKYLWTAVDPLEDMSESKKAKRKVTKMIIIVTVLFCLCWLPHHVVVMCY 261

  Fly   280 SLDVIETNTLTKLVIQVTAQTLAYSSSCINPLLYAFLSENFRKAFYKAVNCSSR 333
            .......|..| ...::.:..:||::||:||::||.:|::|||.|.|..:|..|
Frog   262 LYGDFPFNQAT-YAFRLLSHCMAYANSCLNPIVYALVSKHFRKGFQKVFSCLLR 314

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
AstA-R2	NP_001263042.1	7tm_4	47..>164	CDD:304433	48/118 (41%)
AstA-R2	NP_001263042.1	7tm_1	55..313	CDD:278431	83/262 (32%)
XB5962511	NP_001096443.1	7tmA_Gal2_Gal3_R	27..305	CDD:320225	93/289 (32%)
		TM helix 1	28..54	CDD:320225	10/26 (38%)
		TM helix 2	62..88	CDD:320225	15/25 (60%)
		TM helix 3	100..130	CDD:320225	13/29 (45%)
		TM helix 4	142..162	CDD:320225	2/19 (11%)
		TM helix 5	186..215	CDD:320225	9/28 (32%)
		TM helix 6	231..261	CDD:320225	7/29 (24%)
		TM helix 7	273..298	CDD:320225	8/24 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	185	1.000	Domainoid score	I3318
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	218	1.000	Inparanoid score	I3482
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1294084at2759
OrthoFinder	1	1.000	-	-		FOG0000972
OrthoInspector	1	1.000	-	-		mtm14084
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	5.060