Protein Alignment AstA-R2 and rxfp3.2b

DIOPT Version :10

• Sequence 1: NP_524544.1
• Gene: AstA-R2 / 43393
• FlyBaseID: FBgn0039595
• Length: 357
• Species: Drosophila melanogaster
• Sequence 2: NP_001077348.1
• Gene: rxfp3.2b / 100004589
• ZFINID: ZDB-GENE-050208-346
• Length: 398
• Species: Danio rerio
• Alignment Length: 368
• Identity: 94/368 - (25%)
• Similarity: 175/368 - (47%)
• Gaps: 41/368 - (11%)

  Fly     9 NISLNA---TRNEENITSFFTDEEWLAINGTLPWIVGFFFGVIAITGFFGNLLVILVVVFN-NNM 69
            |:||..   ...:|:.::...|...||:.    .::...:.|:...|..||.|.:.::... .:.
Zfish    33 NLSLRCWLHLLTKESSSTLQGDGSSLAVR----VMIALIYSVVCALGLVGNSLALYLLHSRYRHK 93

  Fly    70 RSTTNLMIVNLAAADLMFVILCIPFTATDYMV-YYWPYGRFWCRSVQYLIVVTAFASIYTLVLMS 133
            :|:.|..::.||..||.|| |.:||.|.|..: :.||:|:..|:.:..:..:..:||::.|..||
Zfish    94 QSSINCFVMGLALTDLQFV-LTLPFWAVDTALDFRWPFGKVMCKIISSVTTMNMYASVFFLTAMS 157

  Fly   134 IDRFLAVV-----HPIRSRMMRTENITLIAIVTLWIVVLVVSVPVAFTHDVVVDYDAKKNITYGM 193
            :.|:.::|     |..|:.....:.|:|    .:|:|.|:.::|.|. :..:......:.:.  :
Zfish   158 VARYYSIVSSLKMHSRRAAAAAAKWISL----GIWVVSLIATLPHAI-YSTIAQVATDEELC--L 215

  Fly   194 CTFTTNDFLGPR----TYQVTFFISSYLLPLMIISGLYMRMIMR--LWRQGTGVRMSKESQ---R 249
            ..|.......|:    .||:...:..:|:||::|:..|: :::|  |.|:.:||..|:..|   :
Zfish   216 VRFPETGSWDPQLLLGLYQLQKVLLGFLIPLVVITVCYL-LLLRIVLSRRISGVAGSETEQGRHK 279

  Fly   250 GRKRVTRLVVVVVIAFASLWLPVQLILLLKSLDVIETNTLTKLVIQVTAQT------LAYSSSCI 308
            .|.:||:.|||||::|...|||.|.:.|...|...:....:|......|..      ||:::||:
Zfish   280 RRSKVTKSVVVVVLSFFLCWLPNQALTLWGVLIKFDLVPFSKAFYNAQAYAFPLTVCLAHTNSCL 344

  Fly   309 NPLLYAFLSENFRKAFYK-AVNCSSRYQNYTSDLPPPRKTSCA 350
            ||:||..:...||....: .:..:..|::....|  |||...|
Zfish   345 NPVLYCLIRREFRAGLKELLLRATPSYRSLARLL--PRKAKVA 385

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AstA-R2	NP_524544.1	7tmA_AstA_R_insect	39..324	CDD:320224	81/306 (26%)
		TM helix 1	40..66	CDD:320224	5/25 (20%)
		TM helix 2	73..99	CDD:320224	11/25 (44%)
		TM helix 3	111..141	CDD:320224	7/29 (24%)
		TM helix 4	153..173	CDD:320224	5/19 (26%)
		TM helix 5	204..233	CDD:320224	8/32 (25%)
		TM helix 6	249..279	CDD:320224	14/29 (48%)
		TM helix 7	292..317	CDD:320224	9/30 (30%)
rxfp3.2b	NP_001077348.1	7tm_GPCRs	62..360	CDD:475119	81/306 (26%)
		TM helix 1	64..88	CDD:410628	5/23 (22%)
		TM helix 2	98..119	CDD:410628	10/21 (48%)
		TM helix 3	136..158	CDD:410628	4/21 (19%)
		TM helix 4	182..198	CDD:410628	5/19 (26%)
		TM helix 5	231..254	CDD:410628	6/22 (27%)
		TM helix 6	285..307	CDD:410628	11/21 (52%)
		TM helix 7	328..353	CDD:410628	9/24 (38%)