Protein Alignment AstA-R2 and tacr1a

DIOPT Version :10

• Sequence 1: NP_524544.1
• Gene: AstA-R2 / 43393
• FlyBaseID: FBgn0039595
• Length: 357
• Species: Drosophila melanogaster
• Sequence 2: NP_001257407.1
• Gene: tacr1a / 100003539
• ZFINID: ZDB-GENE-060526-185
• Length: 426
• Species: Danio rerio
• Alignment Length: 373
• Identity: 98/373 - (26%)
• Similarity: 172/373 - (46%)
• Gaps: 62/373 - (16%)

  Fly     3 NTTMLANISLNAT-RNEENI-TSFFTDEEWLAINGTLPWIVGFFFGVIAITGFFGNLLVILVVVF 65
            :|...:|.::|:| :||..| .:.|....|..:    .|.|.  :..|.:....||:.||.:::.
Zfish     7 STDFPSNWTVNSTAQNETEIYWNQFVQPVWRIV----LWAVA--YSTIVVVSVVGNITVIWIILA 65

  Fly    66 NNNMRSTTNLMIVNLAAADLMFVILCIPFTATDYMVY----YWPYGRFWCRSVQYLIVVTAFASI 126
            :..||:.||..:||||.|:...    ..|......||    .|.:|.::||...:..:...||||
Zfish    66 HKRMRTVTNYFLVNLAFAEASM----SAFNTVINFVYSVHNEWYFGLYYCRFHNFFPIAAVFASI 126

  Fly   127 YTLVLMSIDRFLAVVHPIRSRMMRTENITLIAIVTLWIVVLVVSVPVAFTHDV---------VVD 182
            |::..:::||::|::||::.||..|:  |.:.|..:||:.|:::.|..:..|.         .:|
Zfish   127 YSMTAIALDRYMAIIHPLQQRMSATQ--TKVVIGVIWILALLLAFPQYYYSDTDQLPGRVVCYID 189

  Fly   183 YDAKKNITYGMCTFTTNDFLGPRTYQVTFFISSYLLPLMIISGLYMRMIMRLWRQ---GTGVRMS 244
            :.     .|.:..|.|       .|.|...:..|.|||:::...|:.:.:.||..   |......
Zfish   190 WP-----EYTLLDFKT-------MYFVCVAVLIYFLPLLVMGCAYLVVGLTLWASEIPGDSSDRY 242

  Fly   245 KESQRGRKRVTRLVVVVVIAFASLWLPVQLILLLKSL--DVIETNTLTKLVIQVTAQTLAYSSSC 307
            :|....:::|.::::|||..||..|||..:..|:...  .:.|...:.:  :.:|...||.||:.
Zfish   243 QEQLTAKRKVVKMMIVVVCTFAVCWLPYHVYFLIHQFYPHLFEHTFIQQ--VYLTIMWLAMSSTM 305

  Fly   308 INPLLYAFLSENFRKAFYKAVNC---------------SSRY-QNYTS 339
            .||::|..|::.||..|.:|..|               |:|| |..||
Zfish   306 YNPIIYCCLNDRFRAGFKQAFRCCPCVPEGSYEGLELKSTRYLQTQTS 353

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AstA-R2	NP_524544.1	7tmA_AstA_R_insect	39..324	CDD:320224	80/302 (26%)
		TM helix 1	40..66	CDD:320224	6/25 (24%)
		TM helix 2	73..99	CDD:320224	8/25 (32%)
		TM helix 3	111..141	CDD:320224	10/29 (34%)
		TM helix 4	153..173	CDD:320224	5/19 (26%)
		TM helix 5	204..233	CDD:320224	7/28 (25%)
		TM helix 6	249..279	CDD:320224	10/29 (34%)
		TM helix 7	292..317	CDD:320224	8/24 (33%)
tacr1a	NP_001257407.1	7tmA_NK1R	39..322	CDD:320668	80/308 (26%)
		TM helix 1	40..66	CDD:320668	7/27 (26%)
		TM helix 2	73..99	CDD:320668	9/29 (31%)
		TM helix 3	111..141	CDD:320668	10/29 (34%)
		TM helix 4	152..173	CDD:320668	6/22 (27%)
		TM helix 5	199..228	CDD:320668	8/35 (23%)
		TM helix 6	247..277	CDD:320668	10/29 (34%)
		TM helix 7	290..315	CDD:320668	8/26 (31%)