Protein Alignment AstA-R2 and si:dkey-202l22.3

DIOPT Version :10

• Sequence 1: NP_524544.1
• Gene: AstA-R2 / 43393
• FlyBaseID: FBgn0039595
• Length: 357
• Species: Drosophila melanogaster
• Sequence 2: NP_001108620.1
• Gene: si:dkey-202l22.3 / 100002553
• ZFINID: ZDB-GENE-131127-471
• Length: 377
• Species: Danio rerio
• Alignment Length: 361
• Identity: 97/361 - (26%)
• Similarity: 170/361 - (47%)
• Gaps: 40/361 - (11%)

  Fly     9 NISLNATRNEENITSFFTDEEWLAINGTLPWIVGFFFGVIAITGFFGNLLVILVVVFNNNMRSTT 73
            |.:|:.:...:.:..|...:..|...   |..:..:..|:.:.| .||..::..::.:..:.:.|
Zfish    13 NTTLSTSNRTDPLDKFSGTQLLLRFK---PLFIPLYALVVVVAG-VGNSFLLACILADKKLHNAT 73

  Fly    74 NLMIVNLAAADLMFVILCIPFTAT-DYMVYYWPYGRFWCRSVQYLIVVTAFASIYTLVLMSIDRF 137
            |..|.||||.||:..:.|:|.||: .:....|.:||..|..:..:...|.|||:.:|..:::||:
Zfish    74 NFFIGNLAAGDLLMCLSCVPLTASYAFDAQGWAFGRPMCHLIPLVQGATVFASVLSLTAIAMDRY 138

  Fly   138 LAVVHPIRSRMMRTENITLIAIVTL--WIVVLVVSVPVAFTHDVVVDYDAKKNITYGMCTFTTND 200
            :.|.:|:|.|:    ::.....|.|  |.|.|.::.|.:. |...||....     ||......:
Zfish   139 VVVAYPVRRRI----SVWGCGAVALGVWAVSLALAAPPSL-HTRYVDLRPS-----GMELVVCEE 193

  Fly   201 F-LGPR----TYQVTFFISSYLLPLMIISGLYMRMIMRLWRQGTGVRMSKESQR---GRKRVTRL 257
            | ||..    .|...|.::||::||:.:|..|..:.:.|.:.......|:..||   .|::...|
Zfish   194 FWLGAERQRLLYSCFFLLASYMIPLLSVSISYCAISVHLRKHTLPGEPSQSQQRWSKQRRKTFSL 258

  Fly   258 VVVVVIAFASLWLPVQLILLLKSLD----VIETNTLTKLVIQVTAQTLAYSSSCINPLLYAFLSE 318
            :|..|:|||..|||:|::.||..||    :::.:.:.  |:||:...:|.||:|.||.:||.|..
Zfish   259 LVASVLAFALCWLPLQVLNLLLDLDSDFQIVDKHYVN--VLQVSCHLIAMSSACYNPFIYASLHS 321

  Fly   319 NFR---KAFYKAVNCSSRY--QNYTSDLPPPRKTSC 349
            ..|   :.::    |..|:  ||..|........:|
Zfish   322 KVRMHLRGYF----CPCRHSGQNLLSRCASRNPATC 353

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AstA-R2	NP_524544.1	7tmA_AstA_R_insect	39..324	CDD:320224	86/302 (28%)
		TM helix 1	40..66	CDD:320224	4/25 (16%)
		TM helix 2	73..99	CDD:320224	13/26 (50%)
		TM helix 3	111..141	CDD:320224	8/29 (28%)
		TM helix 4	153..173	CDD:320224	5/21 (24%)
		TM helix 5	204..233	CDD:320224	8/32 (25%)
		TM helix 6	249..279	CDD:320224	13/32 (41%)
		TM helix 7	292..317	CDD:320224	11/24 (46%)
si:dkey-202l22.3	NP_001108620.1	7tm_GPCRs	39..327	CDD:475119	87/300 (29%)
		TM helix 1	41..65	CDD:410628	4/24 (17%)
		TM helix 2	74..96	CDD:410628	10/21 (48%)
		TM helix 3	113..135	CDD:410628	5/21 (24%)
		TM helix 4	156..172	CDD:410628	5/15 (33%)
		TM helix 5	203..226	CDD:410628	7/22 (32%)
		TM helix 6	256..278	CDD:410628	10/21 (48%)
		TM helix 7	295..320	CDD:410628	11/26 (42%)