Protein Alignment AstA-R2 and tacr2

DIOPT Version :10

• Sequence 1: NP_524544.1
• Gene: AstA-R2 / 43393
• FlyBaseID: FBgn0039595
• Length: 357
• Species: Drosophila melanogaster
• Sequence 2: NP_001314788.1
• Gene: tacr2 / 100002125
• ZFINID: ZDB-GENE-090312-188
• Length: 376
• Species: Danio rerio
• Alignment Length: 334
• Identity: 87/334 - (26%)
• Similarity: 156/334 - (46%)
• Gaps: 55/334 - (16%)

  Fly    17 NEENITSFFTDEEW-LAINGTLPWIVGFFFGVIAITGFFGNLLVILVVVFNNNMRSTTNLMIVNL 80
            ||.:| :.|...:| :|:     |.:.  :.:|.|..|.||:.||.:::.:..||:.||..||||
Zfish    20 NETSI-NLFEQPDWQVAL-----WAIA--YTLIVIISFIGNVTVIWIILAHKRMRTVTNYFIVNL 76

  Fly    81 AAADLMFVILCIPFTATDYMVYYWPYGRFWCRSVQYLIVVTAFASIYTLVLMSIDRFLAVVHPIR 145
            |.:|.........|.....:...|.:|..:|:...:..:...|:|||::..:::||::|::||::
Zfish    77 AFSDASMATFNTVFNFVYALHNDWYFGLGYCKFQNFFPITAMFSSIYSMAAIAVDRYMAIIHPLK 141

  Fly   146 SRMMRTENITLIAIVTLWIVVLVVSVPVAFTHDVVVDYDAKKNITYGMCTFTTNDFLGPRT---- 206
            .|:..|....||.::  |.|...::.|                    .|.:.:..|..|||
Zfish   142 PRLSSTTTKLLIGVI--WTVAFSLAFP--------------------QCYYASTKFYFPRTVCMV 184

  Fly   207 -------------YQVTFFISSYLLPLMIISGLYMRMIMRLWRQ---GTGVRMSKESQRGRKRVT 255
                         ||:...|..|||||:::...|..:..|||..   |......:...:.:::|.
Zfish   185 EWPDDYGGKHQLSYQIAVIILIYLLPLLVMLVTYSLVGQRLWGSEIPGEASDHYQNQMQAKRKVV 249

  Fly   256 RLVVVVVIAFASLWLPVQLILLLKSL--DVIETNTLTKLVIQVTAQTLAYSSSCINPLLYAFLSE 318
            ::::|||..||..|||..:..:|.|.  |:.:.:.:.::.:.:.  .||.||:..||::|..|::
Zfish   250 KMMIVVVTTFAICWLPYHIYFILGSFNRDIYKQHYIQQVYLAIF--WLAMSSTMYNPIIYCCLNQ 312

  Fly   319 NFRKAFYKA 327
            .||..|.||
Zfish   313 RFRSGFRKA 321

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AstA-R2	NP_524544.1	7tmA_AstA_R_insect	39..324	CDD:320224	78/306 (25%)
		TM helix 1	40..66	CDD:320224	7/25 (28%)
		TM helix 2	73..99	CDD:320224	9/25 (36%)
		TM helix 3	111..141	CDD:320224	8/29 (28%)
		TM helix 4	153..173	CDD:320224	4/19 (21%)
		TM helix 5	204..233	CDD:320224	12/45 (27%)
		TM helix 6	249..279	CDD:320224	9/29 (31%)
		TM helix 7	292..317	CDD:320224	7/24 (29%)
tacr2	NP_001314788.1	7tm_GPCRs	35..318	CDD:475119	79/313 (25%)
		TM helix 1	37..61	CDD:320670	8/25 (32%)
		TM helix 2	70..92	CDD:320670	8/21 (38%)
		TM helix 3	108..130	CDD:320670	4/21 (19%)
		TM helix 4	151..167	CDD:320670	5/37 (14%)
		TM helix 5	196..219	CDD:320670	8/22 (36%)
		TM helix 6	249..271	CDD:320670	8/21 (38%)
		TM helix 7	286..311	CDD:320670	7/26 (27%)