DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment htt and htt

DIOPT Version :9

Sequence 1:	NP_001263041.1	Gene:	htt / 43392	FlyBaseID:	FBgn0027655	Length:	3583	Species:	Drosophila melanogaster
Sequence 2:	XP_031751173.1	Gene:	htt / 493287	XenbaseID:	XB-GENE-1013462	Length:	3123	Species:	Xenopus tropicalis

Alignment Length:	3955	Identity:	799/3955 - (20%)
Similarity:	1392/3955 - (35%)	Gaps:	1266/3955 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 RNTECSQKQKITCFQQIAECIMSPSLAGHINYAAHCGTATNVLLLFCEDVDSVVRMSAEENLNKI 84
            ::...::|.::.....|.|.|::.||.....:....|.|..:.||..:|.:|.|||.|:|.|||:
Frog    35 KDPSTNKKDRVNHCLTICENIVAQSLRNSPEFQKLLGIAMELFLLCSDDAESDVRMVADECLNKV 99

  Fly    85 LRSLEKTRVSRILMDLYGEIKRNGNQRSLRICLNLFSYYAPQIKEKHIKWYAVRLLQCMTTISQR 149
            :::|..:.:.|:.::||.|||:||..||||..|..|:..|..::.:..:.|.|.||.|:|.||:|
Frog   100 VKALMDSNLPRLQLELYKEIKKNGAPRSLRAALWRFAELAHLVRPQKCRPYLVNLLPCLTRISKR 164

  Fly   150 KETLLQETLCDFVKHFSRHIQQGLSDSESCKLFETFLDQISSDCAVKRRCSAQNCMSLIENARNR 214
            .|..:||||...:...........:|:|...|.:.|:..:.|.....||.:|.:.:|:..::|..
Frog   165 HEESVQETLAAAIPKIMAAFGNFANDNEIKVLLKAFIANLKSSSPAIRRTAAGSAVSICLHSRRT 229

  Fly   215 SLMARHGVNKVMELLLTDQQANS---VLGALGLLRLLLPQLIRGYPGDSHEDSESLAGKKQQQQQ 276
            .......:|.::.||:..:..:.   :||.|..||.|:|.|.:.....|.:.|..:.    |::.
Frog   230 QYFYTWLLNVLLGLLIPVEDEHPTLLILGVLLTLRYLMPLLQQQVKDTSLKGSFGVT----QKEA 290

  Fly   277 TTTSDCRQIIEIYDYCLHLLSTQHTANHAIINATLEVINGILQAVDAASDGQCSQSLGQSLRQLL 341
            ..:....|:|:||:..||.  ||| .:|.::...||::
Frog   291 DISPSAEQLIQIYELTLHY--TQH-RDHNVVTGALELL--------------------------- 325

  Fly   342 CNQQLQHNEYLRRRKSLKNQIFQ---LKNYEVATSQHQLEDEDENEDVDELVVGATAMQMKKNSN 403
                              .|||:   |....|.|:...:|
Frog   326 ------------------QQIFRTPPLDLLHVLTTPGSIE------------------------- 347

  Fly   404 AKLQQAKCREQQQHQHQQQLEVDNSSLGINAGEDAPTEAPSSVAD--EGGEPESTKLRCHIRNAA 466
               |.:.||::...:.:.                      .|:.:  |...||.|:..| :...:
Frog   348 ---QVSVCRDEPYSRSRS----------------------GSIVELIEAVLPEFTRSSC-VAGGS 386

  Fly   467 RSISECVASDEDKQGQGHRQQRDEDGVVVAEDDDDDDDDDDDDDDMELLSAECDDFTTLSQLNEQ 531
            .:.|..:|    ::.:|.....:|:|:               |||:|
Frog   387 STCSPVIA----RKQKGKIHLGEEEGL---------------DDDLE------------------ 414

  Fly   532 QQALSAALKLPTTTAASSGGAATSQDDKLIDVDADVGGLPKPQHQSSLQNL---LAGSDDKSQHL 593
                      ..:.|.::..|||..     :|.:||..|......::|:..   :.....:|||.
Frog   415 ----------GKSDAPATPFAATKN-----EVPSDVTNLSSTAPGANLEGASHDIITEQPRSQHT 464

  Fly   594 SDIDNESFNSIDFDAEITIAGSKEQQQQHPPADDSVESGDATAIGTFFNNLLSHSNAASESVSKL 658
            ...|:...:|.|..:.:| .|.:|....|..:..|....|...      .|...:..||..|
Frog   465 LQSDSVDISSSDLASTVT-EGDEEDILSHSSSQISTVQSDTNM------ELNEGTTQASSPV--- 519

  Fly   659 FRQSSGSKSTPSKSASTPAPADKSDAISAASLTLSLTSLASSNLEPPERQPLIAETPTPVE---- 719
               |..|::|.....|...|:|.|:.:..|:.: ..:.:....|:..|.:..|.......|
Frog   520 ---SDSSQTTTEGPDSAVTPSDSSEIVLDAAES-QYSGMQIGQLQDEEDEGAILHQEEAGEHFGS 580

  Fly   720 DSCSITASHTAST---ALMMDAPAVEVAASKPETPQLRGTPNANPFLVENSPLRQTVVGRALITV 781
            .|..:..:|...|   :......:||....|.|.        .:|..:||.|.|        |..
Frog   581 SSLGLNQTHLLKTMGHSRQSSDSSVERFVPKEEP--------VDPGDLENKPSR--------IKG 629

  Fly   782 KIGSILEQSL--VYYTARLVAARFLLSGQAAGLQPDSISRVSIKSLSLAVIAQCVRLAP-----K 839
            .||..:::..  :.:..||::|.|||:||.:.|.||...|||:|:|:::.:...|.|.|     |
Frog   630 DIGHYMDKDAAPLIHCVRLLSASFLLTGQKSVLVPDRDVRVSVKALAVSCVGAAVALLPESFFSK 694

  Fly   840 ILQLSLEISE-QELQLLEEATSQIGSGDSTQVSSPQSSDNSQVGGEKPPLDSSLVPTSLEENLLL 903
            :.:|..|.:| ||:|.:.:..:.|..||      ||
Frog   695 LYKLPTETTESQEIQYVSDILNYINHGD------PQ----------------------------- 724

  Fly   904 LDIKDDHFGPSTCPAYLQSATPTLSRSADASVLLLEGGTTSSRSAKKSEEMLSKSEIIESSYRPT 968
                            ::.||..||.:...|||        |::..::|..:||   ::::...|
Frog   725 ----------------VRGATAILSGTIVFSVL--------SKAHFEAETWISK---VKANTGNT 762

  Fly   969 VAVEDVPPLSMPPRPPKRTKSTRSRVGVLGTSSTTESSSPQSRQKLSDILLFHDHCDPILRGGVQ 1033
            .:|:|..||..        ||.:..      ||.|        .||:.:.:  .||  |:.
Frog   763 FSVQDCIPLLQ--------KSLKDE------SSVT--------CKLACMAV--RHC--IMT---- 797

  Fly  1034 QVVGNFLQSSGAGLFLDLQRGLGLQHLLAILLKGFEDEIHTVVIQALNAFDKIFPNVVSKYLTEP 1098
                         |.......||||.::.:|
Frog   798 -------------LCCSTYSELGLQLIIDLL---------------------------------- 815

  Fly  1099 PCHYHAHQQQQQQQKEQQQQEQDNQKLEQDLQRHSSGQQKRSGQAQTFGQQTFAKDQDNALSSQR 1163

Frog   816 ----------------------------------------------------------------- 815

  Fly  1164 QQQRRPNDAGTCANSSATDNDELLAALLNDFQLQSTGMRQQPKNNSTDTGQSGNEPDLEPNPNAA 1228
                      |..|||
Frog   816 ----------TLKNSS------------------------------------------------- 821

  Fly  1229 VEPFCVFAISPKLLLSKLRLCHHNKYWLVQNKYAEVISNLNYVLLRSYYANF-RCAIDNKNSGAR 1292
                                     ||||:.:..|.::.:::.|:     || ....:|.:.|..
Frog   822 -------------------------YWLVRTELLETLAEIDFRLV-----NFMEARTENLHRGLH 856

  Fly  1293 KQDSKWPPMDASSVCHSVRDAEGEDIVCTYEAQFLAELLHLLGDDDARVREHAACCLCRFIMQTA 1357
            ..         :.:.| ::|....:::           :.||||||||||..||..|.|.:
Frog   857 YY---------TGLLH-LQDRVLNNVI-----------ISLLGDDDARVRHVAAASLARLV---- 896

  Fly  1358 RQDPSQDQGAGGGGGDDIEGNGNVNVETQQTNFNLLWDFFDYRIFGSMSV-TLRNLFRASSTIVP 1421
               |......     |.::.:..|.....|::..|.....:.:.....:| |:..::|..:....
Frog   897 ---PKLFYNC-----DQVQADPVVAAARDQSSIYLKLLMHETQPPSHFAVSTITRIYRGYNIQQS 953

  Fly  1422 PLAELDALATSNSAPSYPDTGSTSGSSTSTSASSGGSAAAVSAAS-AYFEASYGIGIAEGHVFAL 1485
            |    ..::..|:........|.:.::::|.|.:.|...|:...| .|...::.||...|:|.:.
Frog   954 P----TDISMENNISKVITAVSHALTTSTTRALTFGCCEALCLLSITYPVCTWSIGWHCGYVTST 1014

  Fly  1486 ASASQR-QIAQEEKVLAKVLYRLTNKLMTLND--------KNVQFGIIYALRLLLRHFNFVDYQQ 1541
            ::.:.| |:           |:...:..:::.        |:...|:...:..||        ..
Frog  1015 SAQTSRIQV-----------YKNRGRSFSISQQSPSEEPRKSCTAGMSSMILSLL--------SS 1060

  Fly  1542 VWLEFNFVEICISYAYYNNATAADLGCQNDLIDVMGKLMAGAMLSS------GEPNTAH------ 1594
            .|...                  ||....|.:.::|.|:|.....|      .|..|:.
Frog  1061 AWFPL------------------DLSAHQDALVLVGNLLAATAPKSLKNPWTSEEETSQGANKQE 1107

  Fly  1595 --------------LDFLLRHSVKMLNIYYHLVTNQRP--------------------------- 1618
                          :|.|..|.:|.:||..|::.:..|
Frog  1108 EPWPALGDRAVVGMVDQLFIHLLKAINICAHVIDDITPGPVVKATLPSLTNPPSLSPIRRKGKER 1172

  Fly  1619 --------PTAGSQSGSSSSKQPKSELFAREQPAATLQALGYFAGDYVYMKLYNILRGANDSYKI 1675
                    |.:..:||.::   |.|.......||.|.:::|.|.....|:|||::|:....:||:
Frog  1173 DTAEQAAVPLSPKKSGEAT---PASRQTEASGPAQTSKSIGSFYHLPSYLKLYDVLKATYANYKV 1234

  Fly  1676 TI-----NQEAGSLLICLLKTCLHAVSLCLEGMASASPPELKLIEEILHYLTRLINYAPAECVAC 1735
            ::     |::.|.    .|::.|..:|..|| :|:.: ...|.:||||.||....:..|.....|
Frog  1235 SLDLQNNNEKFGG----FLRSALDVLSQILE-LATLT-DIAKCVEEILGYLKSCFSREPVMATVC 1293

  Fly  1736 LRQLLKYLFAQNYASQ---VRLQPSAIGGNGSEIG--------HHAAFMRPYFAAKGRGHGASST 1789
            ::||||.||..|.|||   :...||...|....:|        :|..||.||
Frog  1294 VQQLLKTLFGTNLASQFEAMSSNPSKCQGKAQRLGSSNLRPGLYHYCFMAPY------------- 1345

  Fly  1790 LLPTINSKPAVAVGSQRGAPTDARQPIDAG----PLQDMGMLFVHGLQPPTPPAGDCVRL---IK 1847
                .:...|:|..|.|.. ..|.|..|..    .||.:.....:.:...|....|...:   |:
Frog  1346 ----THFTQALADASLRNM-VQADQEQDTSGWFDVLQKVSSQLKNSISNVTKHRTDKNAIHNHIR 1405

  Fly  1848 LFEPMVIYCLTLFMKSNAL-VQAPILRLLSQLLDLNVTYSILDSKNVIFDQVLSNMDLIEGGIDR 1911
            ||||:||..|..:..:.:: :|..:|.||:||:.|.|.|.:|||..|....||...:.||.|..|
Frog  1406 LFEPLVIKALKQYTTTTSVQLQRQVLDLLAQLVQLRVNYCLLDSDQVFIGFVLKQFEYIEVGQFR 1470

  Fly  1912 NAFIMVPPMLRFLVQLTHK--SDRQLITIPKIISITNNLLANGSVRVV-ALLALKTLSYELFFMH 1973
            .:..::|.:..|||.|:::  ..:|:|.|||||.:.:.::|:|...|. |:.||:.:.::||.:
Frog  1471 ESEAIIPNVFFFLVLLSYERYHSKQIIGIPKIIQLCDGIMASGRKAVTHAIPALQPIVHDLFVL- 1534

  Fly  1974 SQLEEALDTEGHNSGRDACQSPLSAAPTPETREALLAQRRELDTQREVVLGMLEKFIEARPSQQV 2038
                     .|.|.. ||                    .:||:||:|||:.||.:.|:   ..||
Frog  1535 ---------RGANKA-DA--------------------GKELETQKEVVVSMLLRLIQ---YHQV 1566

  Fly  2039 LALLLLFERSVQQLDTPPYR--SAQDADAVYGTLCRGLCSRQWRLHNAGDLRLLESCFRNNGNHV 2101
            |.:.:|..:...:.:...::  |.|.||.:...|.:    :|..:.:...|.::.:.|.......
Frog  1567 LEMFILVLQQCHKENEDKWKRLSRQIADVILPMLSK----QQMHIDSHDALGVINTLFETLAPSA 1627

  Fly  2102 LADSKRFLQ-------------LLQLFIEQGVGNFGDLALAMVMLSNVILKTEEIYLVNHIKLYL 2153
            |......|:             .:||:|.      |.||:..|::|.   .||:|.|....:|.|
Frog  1628 LRPVDMLLRSMFVVPCTMASVSTVQLWIS------GILAILRVLISQ---STEDIVLSRIQELSL 1683

  Fly  2154 KNNPTAERRLQALM----PSSPSAAPHWQDEAPSTSSAAAAARAAAASFSAGRSSISEINYFAKV 2214
            .......:.:..|.    |..|...|...:..|:....                       |::.
Frog  1684 SPKLICCQNIMNLREGDNPLPPEVYPEQSENKPAPEET-----------------------FSRF 1725

  Fly  2215 LCEKLLACLEVL----LGLEPSSSSHA-YCQLTGRFMDALLNVCCRSRHKDALQSVFRLVLAESE 2274
            |.:.:...||.:    |.::.|...|. |||..|..:..|:::......:....:..||...:..
Frog  1726 LLQLVGILLEDIVYKELKVDLSEQQHTFYCQQLGTLLMCLIHIFKSGTFRRITNAAMRLFKGDGS 1790

  Fly  2275 FLCKYYSLLLMSAAGLVGSYL---LDAVLLACLRLVLAMRLEEPVALLEQAAQLPLKTNLQRALL 2336
             ...:|:  |.|..|||.|..   ...|||.|..|:|.....  .:...:..|.|.:.:|....|
Frog  1791 -NGSFYT--LESLNGLVESMFPTHPSLVLLWCQFLLLINYTN--YSWWSEVHQTPKRNSLSSTKL 1850

  Fly  2337 ----------------------REVCRASA---GCDWSAQQVRRLFEGRYLNFLIADHLEFICEL 2376
                                  ||:.|..|   .||:..|   .|.:..:|.:||.:|::.:..|
Frog  1851 LSPHMSTESDDPDLTSKPGICNREIVRRGALILFCDYVCQ---NLHDSEHLTWLIVNHVQDLINL 1912

  Fly  2377 CQERPECGSLLQVALFRNA-HRLSRQSVRIVLRLLGRLCEPAEREASGDVGSDADPT--LQAMQL 2438
            ..|.|       |..|.:| ||.|..|...:..:..| ||           :.|.||  .:.:|.
Frog  1913 SHEPP-------VQDFISAIHRNSAASGLFIQAIQSR-CE-----------NLAAPTSLKKTLQC 1958

  Fly  2439 LSRLHQLYEG-------ERSLQLPIERMARRLSAQSGQPARNVIYERLVEGDLAGGEDQDALRTL 2496
            |..:|....|       ::.|..|...:||.:         :.:..|.||..|| ...|:::..|
Frog  1959 LEGIHLSQSGAVLLLYIDKLLCTPFRVLARMV---------DTLACRRVEMLLA-ATPQNSISQL 2013

  Fly  2497 LLKDLECRQDNETATPSRIIDESWLFAQLIKFATQHADAPQQQKQLMLL--------------LL 2547
            .:::|:..|:               :.|....|.:|      |:...||              |.
Frog  2014 PMEELDRMQE---------------YLQSSGLAQRH------QRLYSLLDRFRMTVAPDTVSPLP 2057

  Fly  2548 EIQSEPKLQRLLRSLGTEHEAKLLRHAIAGSLAAMMSAFRQKCIQHAPHINYMQPTPLARVSCAL 2612
            .:.|.|        |..|::|.|  ..:.......:|..|.:|..|:..         |.:..|.
Frog  2058 SVTSHP--------LDGENQATL--ETLDPDKEWYVSLVRSQCFTHSDS---------ALLEGAE 2103

  Fly  2613 LMSRVASTEATKCRNPPTGEQLDVARAVGALMACIR------NAEQ---------TALIYIDARL 2662
            |::::.:.|.   .:..|.:..:|:    .|..|:.      :.||         |.::.:.:..
Frog  2104 LVNKIPAAER---HSFMTSKNFNVS----LLAPCLALGVHQISGEQDSSFFKTTLTVIVDLLSGS 2161

  Fly  2663 MEKFVVEH-LLRREHLPQLLAY---LGWLAG--------------AAKQILAMP-------TRQE 2702
            :|:....| :|:.....:..||   |..|.|              .|:.::::|       .:||
Frog  2162 VEQLPAGHQVLQPLQQVESTAYWEKLSLLFGDSSVYCSLVALCRALAQYLVSLPKLPAEFHIQQE 2226

  Fly  2703 SEQDALGVLLATVNTL-------------------------LQQPRVWRELNASSDPSLRCELLD 2742
            .|.|.:..::..|..:                         ||||.:|..|.:|...:..|.|:
Frog  2227 KEVDFVKFMVLCVEAISWHLVHEQVPLSMDLQAVIDYCCLTLQQPALWNLLASSEYVTHACSLI- 2290

  Fly  2743 LLDSVARCILQ-------DTIFYRRHRRDRNKAKGPAPQA-------IFLAKLIETQIE-IESLA 2792
               ...|.||:       |.:.....|:::........|.       :|:....|...| :|||
Frog  2291 ---MCVRFILEAVAVEPGDQLLSPERRKNKMSEDSEEDQVDSSEQKHVFIKTACEMMAEMVESL- 2351

  Fly  2793 SGRVLAGVEEARLQFAGQDLARFQVALSLV-TSIGISLLRTHQFYAYAVTPHELIQQPGDQQQEQ 2856
                     :..|.|..|....|...|:.| .:|.|||.|.....:|...| .|:.:.|...:..
Frog  2352 ---------QTILVFGHQKNRNFSAFLTPVFRNIIISLARLPLVNSYTRVP-PLVWKLGWAPKWG 2406

  Fly  2857 QADG-KLPSIPVDSLSDVDVLRQFVKRLSIFGFTTRQQFEEYFMTCLLLINKLYDEHMV-----D 2915
            ...| .||.|||:.|.:.:|.|:|:..::..|:|:|.||||.:.|   |:..|..:.||     :
Frog  2407 GEFGTSLPEIPVEFLQEKEVFREFIYCINTLGWTSRTQFEETWAT---LLGVLVTQPMVMDQDEN 2468

  Fly  2916 QQEQ----FQIKQVCLQAILELLMTYKTFPIVGLANGQF-------------------------- 2950
            |||:    .||..:.:|||..|:::..|..:.|.....|
Frog  2469 QQEEDTERTQINVLAVQAITSLVLSAMTITVAGNPAISFLEQQPRNKSLKALDTRFGRKLSVVRG 2533

  Fly  2951 ------------------HHTTR-WQRITCDSISLKKLHKVQLLVDACNVFYQPNLERQLAYDNV 2996
                              ||:.: |     |.:..........|::...:..|.|.||:
Frog  2534 IVEEEIQAMVSKRDNIATHHSCQAW-----DPVPSLSAPTTGTLINQERLLLQINTERE------ 2587

  Fly  2997 IGTRTFAPNQYDLNFSWAQMEDQAAAGVGVGVGVGLSGGEQ----ANTADIKQSCDADVPDMAMR 3057
            ||..::...|..::..|              :|..::...|    .:..|..::.....|.|:..
Frog  2588 IGNMSYKLGQVSIHSVW--------------LGNNITPLRQEELDEDEEDENENPTPSSPPMSPI 2638

  Fly  3058 NYRHFTQLSGIDFRSSTQLVFDVLQQMI-------ELNHIL---VLPNLVKFCEICESRDHIKWI 3112
            |.|  ...:|:|..|.:|.:.::..|.|       :...||   |:.:|:...::...|:..:.:
Frog  2639 NSR--KHRAGVDIHSCSQFLLELYSQWILPTNTGKKTPAILISEVVRSLLTVSDLFTERNQFEMM 2701

  Fly  3113 KERCLKLQEQVAMDDTISHQHIIYLLCRSQALLIPSLGELQVLCSLIGNVY---LKSTHSFIRIA 3174
            .....:||:|...:|.|.:|:::..:|::.|:    ||..:|:...:..:.   |:|||...||.
Frog  2702 YTALTELQKQHPSEDEILNQYLVPAICKAAAV----LGMDKVIAEPVSRIIETTLRSTHMPSRIG 2762

  Fly  3175 TLQGLLCLLECCSKTNTTMGRLSEELA--LLRSL--IVGYINRHGIIDESPLPFSVEHTKLVWTL 3235
            .|.|:|.:|| |...:.|..:|...::  ||.:|  |...:|.|          :.:|..::...
Frog  2763 ALHGILYILE-CDLLDDTAKQLIPVISDYLLSNLRGIAHCVNLH----------NQQHVLVMCAT 2816

  Fly  3236 NYSLI---------EWTSKFVPQCHLLSNTIIAANNFLKTTADEE-----LYLCVLHGLERMVVN 3286
            .:.||         |:||..:..|.::            .:..||     :|.||:.||||::::
Frog  2817 AFYLIENYPLDVGPEFTSGIIQMCGVM------------VSGSEESTPSMVYHCVMRGLERLLLS 2869

  Fly  3287 SGVPPPGIQPTGKDAAAGEPGAEGSKAGVGVVVTPQMRHKIEKLALELLKMENEKFSIPALKLLL 3351
            .       |.:..|..|                       :.||:::.:.|.:...::.||.|:|
Frog  2870 E-------QLSRLDGEA-----------------------LVKLSVDRVNMHSPHRAMTALGLML 2904

  Fly  3352 SCMYVGSAAQLENTELSNGIVQD------DPEIIAQQNDKVDILLHCIKSSTRDAAWIYGQVLCQ 3410
            :|||.|      ..::|.|...:      |.|.:....::|.:|...|:......|.:..::|.|
Frog  2905 TCMYTG------KEKISPGRATEPSPAAPDSESVIVAMERVSVLFDRIRKGFPFEARVVARILPQ 2963

  Fly  3411 IIRDLVPPNEILTKVIKEFLAINHPHCDVIAMIVYQVFRSAIDSSYLQMLQDWLICTLPTFLDQ- 3474
            .:.|..||.:::.|||.|||:...|:...:|.:||:||::...:....|::||::.:|..|..:
Frog  2964 FLDDFFPPQDVMNKVIGEFLSNQQPYPQFMATVVYKVFQTLHATGQSSMVRDWVMLSLSNFTQRT 3028

  Fly  3475 PEQQGVWGLSVIFLSASINLHLIKLFPLVLGIGASNSAAAATTATTATTEAEAAAPAMARKLGQH 3539
            |....:|.||..|:|||.:..:..:.|.|:.                             ::|:.
Frog  3029 PVAMAMWSLSCFFVSASTSKWISAILPHVIS-----------------------------RMGKS 3064

  Fly  3540 E---IALFVTAAQDFHAKLSGEQ--RQRFREAF------GSFKRSQVYGRMLQCL 3583
            |   :.||...|.||:.....|:  |:.|:..|      ||     .|.|:|.||
Frog  3065 EPVDVNLFCLVAIDFYKHQIDEELDRRSFQSVFELVASPGS-----PYYRLLLCL 3114

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
htt	NP_001263041.1	DUF3652	2726..2757	CDD:289166	8/37 (22%)
htt	XP_031751173.1	HEAT repeat	76..98	CDD:293787	10/21 (48%)
		HEAT repeat	112..140	CDD:293787	13/27 (48%)
		HEAT repeat	153..183	CDD:293787	12/29 (41%)
		HEAT repeat	192..221	CDD:293787	7/28 (25%)
		DUF3652	1495..1535	CDD:403547	6/48 (13%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	307	1.000	Domainoid score	I1347
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	478	1.000	Inparanoid score	I1440
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D33894at2759
OrthoFinder	1	1.000	-	-		FOG0008164
OrthoInspector	1	1.000	-	-		oto103221
Panther	1	1.100	-	-	LDO	PTHR10170
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6127
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	8.160