DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment snu and CAF16

DIOPT Version :9

Sequence 1:	NP_651628.1	Gene:	snu / 43391	FlyBaseID:	FBgn0039594	Length:	808	Species:	Drosophila melanogaster
Sequence 2:	NP_116625.1	Gene:	CAF16 / 850516	SGDID:	S000001866	Length:	289	Species:	Saccharomyces cerevisiae

Alignment Length:	315	Identity:	80/315 - (25%)
Similarity:	140/315 - (44%)	Gaps:	60/315 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    70 TQAAVSVRHAFKAYGKKKNANQVLNNLNMTVPKGTIYGLLGASGCGKTTLLSCIVGRRYMDAGEI 134
            :|.|:.||:.  .|..|::::..:.::|:.:|..|...::||:|.||:|||..:.|:.....|:|
Yeast     3 SQFAIEVRNL--TYKFKESSDPSVVDINLQIPWNTRSLVVGANGAGKSTLLKLLSGKHLCLDGKI 65

  Fly   135 FVLGGKPGTRGSGVPGKRVGYMPQEI-ALYGEFSIQ-----ETMMYFG--W----IFGMD--TKE 185
            .|.|..|             :.|..: .:..:.|::     :|..|.|  |    |...|  ..|
Yeast    66 LVNGLDP-------------FSPLSMNQVDDDESVEDSTNYQTTTYLGTEWCHMSIINRDIGVLE 117

  Fly   186 ILERLQF---------LLNFLDLPSEKRLVKNLSGGQQRRVSFAVALMHDPELLILDEPTVGVDP 241
            :|:.:.|         |:..||:....|: ..||.||:|||..|:.|:....:|:|||.||.:|.
Yeast   118 LLKSIGFDHFRERGERLVRILDIDVRWRM-HRLSDGQKRRVQLAMGLLKPWRVLLLDEVTVDLDV 181

  Fly   242 LLRQSIWNHLVHITKAGQKTVIITTHYIEE-ARQAHTIGLMRSGHLLAEESPSVLLSIYKCISLE 305
            :.|..:...|...|:..:.:|:..||..:. |:..:.:..|:||.::..      |...|.:...
Yeast   182 IARARLLEFLKWETETRRCSVVYATHIFDGLAKWPNQVYHMKSGKIVDN------LDYQKDVEFS 240

  Fly   306 EVFLKLSRIQSQ-KGDVTHVNFSNNI------SLHAMAF-GSKMDKPSSSQEGGV 352
            ||      :.:: .|.|...|.:|.:      |||.:|. ..|.|.....:|.|:
Yeast   241 EV------VNAKVNGQVAFENDNNKVVISKVNSLHPLALEWLKRDNQIPDKEIGI 289

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
snu	NP_651628.1	LolD	73..290	CDD:224059	63/240 (26%)
		ABC_DR_subfamily_A	74..286	CDD:213197	62/235 (26%)
		pip_yhgE_Nterm	427..>474	CDD:276270
		ABC2_membrane_3	429..801	CDD:289468
		ABC2_membrane	601..769	CDD:279410
CAF16	NP_116625.1	COG4586	1..289	CDD:226952	79/313 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm46598
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R16705
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.940