Protein Alignment snu and Abca6

DIOPT Version :10

• Sequence 1: NP_651628.1
• Gene: snu / 43391
• FlyBaseID: FBgn0039594
• Length: 808
• Species: Drosophila melanogaster
• Sequence 2: XP_006247716.1
• Gene: Abca6 / 303639
• RGDID: 1308998
• Length: 1630
• Species: Rattus norvegicus
• Alignment Length: 825
• Identity: 168/825 - (20%)
• Similarity: 303/825 - (36%)
• Gaps: 254/825 - (30%)

  Fly    63 PANGPRNTQAAVSVRHAFKAYGKKKNANQVLNNLNMTVPKGTIYGLLGASGCGKTTLLSCIVG-- 125
            |.:.....:.|:.:|:..|.|..|....:.|..|...|.:..|..:||..|.||::||:.:.|
  Rat   471 PVDPEYQGKEAIRIRNIRKEYKGKSGKVEALKGLFFDVYESQITAVLGHGGAGKSSLLNILNGLS 535

  Fly   126 --------------RRYMDAGEIFVLGGKPGTRGSGVPGKRVGYMPQEIALYGEFSIQETMMYFG 176
                          ....|..||               .|.:|..||....:...:::|.:..|.
  Rat   536 VPTSGLATVYNKNLSEMQDLKEI---------------RKMIGVCPQHNVQFDALTVKENLTLFA 585

  Fly   177 WIFGMDTKEILERLQFLLNFLDLPS-EKRLVKNLSGGQQRRVSFAVALMHDPELLILDEPTVGVD 240
            .|.|:..:.:.:.:|.:|:.||:.: :..|.::||.||:|:::|.||::.||.:|:|||||.|:|
  Rat   586 NIKGIVPQSVAQEVQQILSELDMQTIQDELAEHLSEGQKRKLTFGVAILGDPRILLLDEPTAGLD 650

  Fly   241 PLLRQSIWNHLVHITKAGQKTVIITTHYIEEARQAHTIGLMRSGHLLAEESPSVLLS--IYKCIS 303
            |..||.:|..|..  :...:.::.:|.:.:||            .:||:.  .|:||  ..||..
  Rat   651 PFSRQRVWGFLKE--RRADRVILFSTQFTDEA------------DILADR--KVILSNGALKCTG 699

  Fly   304 LEEVFLK--------LSRIQSQKGDVTHV-NFSNN----ISLHAMA------------------F 337
             ..||||        ||...::..|...: :|.|:    ..|.|..                  |
  Rat   700 -SSVFLKRKWGLGYHLSLFMNETCDSEQLTSFINHHIPGAKLKAKTKEKLVYTLPLEKTSKFPEF 763

  Fly   338 GSKMDKPSSSQEGGVVGLNFHQSKEVLINDSNGSIYTLNQEPYSPPPSRRNNNPNDEESCQDCYS 402
            .|.:||.|..      ||   .:.||.::..|.....|..||.:.....:.....|.:|.
  Rat   764 FSDLDKYSGQ------GL---MNYEVSMSTLNEVFMNLEGEPSTTQDFEKGETLTDSDSL----- 814

  Fly   403 NLCKITSKGKIRALLTKNMLRMWR-------NVGVM-------LFIFALPVMQVI---------- 443
            |..::......:|..|.:.:.:||       .:.|:       .|:..||::.:.
  Rat   815 NEMEVAPPSLSKAQKTMSAMSLWRMQVCAIARLRVLKLRRERKAFLTFLPLLGISLIPLITEYMA 879

  Fly   444 ---------------LFCLAIGRDPQGLN---LAIVNGEMN--DTVRENCYWEDGCHFKNLGCRY 488
                           |:.|:.|:.||||.   |.|.|.|.|  |.|:.
  Rat   880 NALIEVKTNWEFKTDLYFLSPGQLPQGLRTSLLVINNTESNIEDFVQS----------------- 927

  Fly   489 LSHLNTSVVKTYYEDLDD--AKEAVRKGTAWGAVYISENFTDAFIARANLGRDSDDETIDSSEVK 551
            |.|.|..:      ::||  .:.|....:..||:.:|             ||..|.........|
  Rat   928 LKHQNIVL------EVDDFENRNATESLSYNGAIIVS-------------GRQKDYRFSAVCNTK 973

  Fly   552 ------VWLDMSNQQIGVMLNRDIQLAFRDFAMGLLGQCGSNPKLGDVPIQFRDPIYGTMNPSFT 610
                  :.:::.:..|..|||....:...:..:          ..|.|.:.|     |.:..|
  Rat   974 RLHCFPILMNVISNGILRMLNHTQHIRLEEDVL----------SSGIVVVWF-----GILEAS-- 1021

  Fly   611 DFVAPGVILTIVFFLA-----VALTSSALIIERTEGLLDRSWVAGVSPF-----EILFSHVITQF 665
                    |:|:|.:.     :|::|.:...::.:..|   |::|:.|.     :.|....:...
  Rat  1022 --------LSILFIVCSVSPHIAMSSISDFKKKADSQL---WISGLYPSAYWCGQALVDITLLSG 1075

  Fly   666 VVMCGQTTL--------------VLIFMLVVFGVTNNGDLFWVIVLTLL-------QGMCGMCFG 709
            :::.|..||              ||..:|:.||...: .:|...|::.:       .|:..:||.
  Rat  1076 ILLTGYITLYTTKLMHIYLTGEIVLSIVLLAFGCAAS-LVFLTYVISFVFGKKRKNSGLWSICFF 1139

  Fly   710 FLISSVCELERNAIQLALGSFYPTLLLSGVI----WPIEGMPVVL 750
            .:|:.:.:      .:.:..|...||:|.::    :.:..:.:||
  Rat  1140 IVITIMFD------TVLMDPFNEALLISAMMLVPSFSLNALLIVL 1178

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
snu	NP_651628.1	CcmA	74..311	CDD:440746	69/263 (26%)
		YadH	609..807	CDD:440604	30/177 (17%)
Abca6	XP_006247716.1	rim_protein	<173..1606	CDD:130324	168/825 (20%)