DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment snu and Abca7

DIOPT Version :9

Sequence 1:	NP_651628.1	Gene:	snu / 43391	FlyBaseID:	FBgn0039594	Length:	808	Species:	Drosophila melanogaster
Sequence 2:	NP_997481.1	Gene:	Abca7 / 299609	RGDID:	1303134	Length:	2170	Species:	Rattus norvegicus

Alignment Length:	312	Identity:	85/312 - (27%)
Similarity:	138/312 - (44%)	Gaps:	48/312 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 RHFSWSDPSAIISTDSAMAATNNDGGTQPNAVAAWGAPANGPRNTQAAVSVRHAFKAYGKKK--- 87
            |...|..|..  ...|.:|....|    |..:.....|...|     .||:|      |.||
  Rat   768 RRSYWCGPGP--PKSSVLAPAPQD----PKVLVEEPPPGLVP-----GVSIR------GLKKHFR 815

  Fly    88 -NANQVLNNLNMTVPKGTIYGLLGASGCGKTTLLSCIVGRRYMDAGEIFVLGGKPGTRGSGVPGK 151
             :....|..||:...:|.|...||.:|.||||.||.:.|.....:|...:||....|..:.: ..
  Rat   816 GSPQPALRGLNLDFYEGHITAFLGHNGAGKTTTLSILSGLFPPSSGSASILGHDVQTNMAAI-RP 879

  Fly   152 RVGYMPQEIALYGEFSIQETMMYFGWIFGMDTKEILERLQFLLNFLDL-PSEKRLVKNLSGGQQR 215
            .:|..||...|:...:::|.:.::|.:.|:....|....:.|:..:.| |......::||||.||
  Rat   880 HLGICPQYNVLFDMLTVEEHVWFYGRLKGVSAAAIDSEQEHLIRDVGLIPKRDTQTRHLSGGMQR 944

  Fly   216 RVSFAVALMHDPELLILDEPTVGVDPLLRQSIWNHLVHITKAGQKTVIITTHYIEEAR-QAHTIG 279
            ::|.|:|.:....::|:||||.||||..|:.||..|:...:.  :|:|::||:::||. ....:.
  Rat   945 KLSVAIAFVGGSRVVIMDEPTAGVDPASRRGIWELLLKYREG--RTLILSTHHLDEAELLGDRVA 1007

  Fly   280 LMRSGHLLAEESPSVLLSIYKCISLEEVFLK--------LSRIQSQKGDVTH 323
            ::.||.|....||              :||:        |:.::|.:..|||
  Rat  1008 MVASGSLCCCGSP--------------LFLRRHLGCGYYLTLVKSSQSLVTH 1045

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
snu	NP_651628.1	LolD	73..290	CDD:224059	67/222 (30%)
		ABC_DR_subfamily_A	74..286	CDD:213197	66/217 (30%)
		pip_yhgE_Nterm	427..>474	CDD:276270
		ABC2_membrane_3	429..801	CDD:289468
		ABC2_membrane	601..769	CDD:279410
Abca7	NP_997481.1	rim_protein	1..2127	CDD:130324	85/312 (27%)
		ABC2_membrane	<557..742	CDD:304374
		ABC_subfamily_A	805..1024	CDD:213230	70/241 (29%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1044..1086		2/2 (100%)
		ABC_subfamily_A	1818..2038	CDD:213230
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	2129..2170
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0059
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.900