Protein Alignment snu and ced-7

DIOPT Version :9

• Sequence 1: NP_651628.1
• Gene: snu / 43391
• FlyBaseID: FBgn0039594
• Length: 808
• Species: Drosophila melanogaster
• Sequence 2: NP_001255012.1
• Gene: ced-7 / 176352
• WormBaseID: WBGene00000421
• Length: 1758
• Species: Caenorhabditis elegans
• Alignment Length: 919
• Identity: 192/919 - (20%)
• Similarity: 352/919 - (38%)
• Gaps: 253/919 - (27%)

  Fly    43 MAATN-NDGGTQPNAVAAWGAPANGPRNT-QAAVSVRHAFKAYGKKKNANQVLNNLNMTVPKGTI 105
            ||:|: |......:::......|:|.|:| :|.:.||:..|.:  .....:.::.|::...:|..
 Worm   567 MASTSLNPPNADSDSLLEGSTEADGARDTARADIIVRNLVKIW--STTGERAVDGLSLRAVRGQC 629

  Fly   106 YGLLGASGCGKTTLLSCIVGRRYMDAGEIFV----LGGKPG-TRGSGVPGKRVGYMPQEIALYGE 165
            ..|||.:|.||:|..|.|.|......|.|.:    :|.:|| ||      :.:|..||...||.:
 Worm   630 SILLGHNGAGKSTTFSSIAGIIRPTNGRITICGYDVGNEPGETR------RHIGMCPQYNPLYDQ 688

  Fly   166 FSIQETMMYFGWIFGMDTKEILERLQFLLN--FLDLPSEKRLVKNLSGGQQRRVSFAVALMHDPE 228
            .::.|.:.....:.|...|:..:.::.||:  .||....::.| |||||.:|::...:||:.|.|
 Worm   689 LTVSEHLKLVYGLKGAREKDFKQDMKRLLSDVKLDFKENEKAV-NLSGGMKRKLCVCMALIGDSE 752

  Fly   229 LLILDEPTVGVDPLLRQSIWNHLVHITKAGQKTVIITTHYIEEA-RQAHTIGLMRSGHLLAEESP 292
            :::|||||.|:||..||.: ..||...|| .:|:::||||::|| |....:.:|..|.|:|..:.
 Worm   753 VVLLDEPTAGMDPGARQDV-QKLVEREKA-NRTILLTTHYMDEAERLGDWVFIMSHGKLVASGTN 815

  Fly   293 SVLLSIYKCISLEEVFL-------KLSRI----------QSQKGD-------------------- 320
            ..|...:....|..|.|       |::.|          ::::|:
 Worm   816 QYLKQKFGTGYLLTVVLDHNGDKRKMAVILTDVCTHYVKEAERGEMHGQQIEIILPEARKKEFVP 880

  Fly   321 -------VTHVNFSNNI----------------------SLHAM-----AFGSKMDKPSSSQEGG 351
                   :...|:.:|:                      ||:.:     ..|.|:||..:|:
 Worm   881 LFQALEAIQDRNYRSNVFDNMPNTLKSQLATLEMRSFGLSLNTLEQVFITIGDKVDKAIASR--- 942

  Fly   352 VVGLNFHQSKEVLINDSNGSIYTLNQEPYSPPPSRRNNNPNDEESCQDCYSNLCKITSKG----- 411
                   |:..:..|..|.|..:|....|....|.::         .|.|..|....::|
 Worm   943 -------QNSRISHNSRNASEPSLKPAGYDTQSSTKS---------ADSYQKLMDSQARGPEKSG 991

  Fly   412 ------KIRALLTKNML---RMWRNVGVMLFIFALPVMQVILFCLAIGRDPQGLNLAIVNGEMND 467
                  :..:::.|..|   |.|..      :|...::.:||.         ||..::...:.|:
 Worm   992 VAKMVAQFISIMRKKFLYSRRNWAQ------LFTQVLIPIILL---------GLVGSLTTLKSNN 1041

  Fly   468 T----VR---------ENCYWEDGCHFKNLGCRYLSHLNTSVVKTYYEDLDDAKEAVRKGTAWGA 519
            |    ||         ....|    .|:|              .|..|:..:.::.:||...:..
 Worm  1042 TDQFSVRSLTPSGIEPSKVVW----RFEN--------------GTIPEEAANFEKILRKSGGFEV 1088

  Fly   520 VYIS-----ENFTDAFIAR---ANLGRDSDDETIDSSEVKVWLDMSNQQI----GVMLNR----- 567
            :..:     .|.|.:.|..   |.:|.     |::|..::...:|....:    ..|:||
 Worm  1089 LNYNTKNPLPNITKSLIGEMPPATIGM-----TMNSDNLEALFNMRYYHVLPTLISMINRARLTG 1148

  Fly   568 --DIQLAFRDFAMGLLGQCGSNPKLGDVPIQFRDPIYGTMNPSFTDFVAPGVILTIVFFLAVALT 630
              |.:::...|   |..:..||..|  :|.|..|.:           :||  :|.::|.:..:..
 Worm  1149 TVDAEISSGVF---LYSKSTSNSNL--LPSQLIDVL-----------LAP--MLILIFAMVTSTF 1195

  Fly   631 SSALIIERTEGLLDRSWVAGVSPFEILFSHVITQ---FVVMCGQTTLVLIFMLVVFGVTNNGDLF 692
            ...||.|||.....:.::.|:||.....:.:|..   :.::|    |:.:||.:.|        .
 Worm  1196 VMFLIEERTCQFAHQQFLTGISPITFYSASLIYDGILYSLIC----LIFLFMFLAF--------H 1248

  Fly   693 W-------VIVLTLLQGMCGMCFGFLISSVCELERNAIQLAL-------GSFYPTLLLSGVIWPI 743
            |       ||:...|.....:.|.:.:|.:.:....|..|.:       |:....:.|..:|:.|
 Worm  1249 WMYDHLAIVILFWFLYFFSSVPFIYAVSFLFQSPSKANVLLIIWQVVISGAALLAVFLIFMIFNI 1313

  Fly   744 EG--MPVVLRYISLCLPLTLATSSLRSILTRGWAILESDVYIG--YVSTLSWIVG------FLVL 798
            :.  ..:::......||.....|::.:|.|.| .||.|:..:.  :....:|::|      |.:.
 Worm  1314 DEWLKSILVNIFMFLLPSYAFGSAIITINTYG-MILPSEELMNWDHCGKNAWLMGTFGVCSFALF 1377

  Fly   799 TLLVLRAKR 807
            .||..:..|
 Worm  1378 VLLQFKFVR 1386

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
snu	NP_651628.1	LolD	73..290	CDD:224059	71/224 (32%)
		ABC_DR_subfamily_A	74..286	CDD:213197	69/219 (32%)
		pip_yhgE_Nterm	427..>474	CDD:276270	9/59 (15%)
		ABC2_membrane_3	429..801	CDD:289468	78/430 (18%)
		ABC2_membrane	601..769	CDD:279410	33/186 (18%)
ced-7	NP_001255012.1	ABC2_membrane_3	<286..445	CDD:289468
		CcmA	600..885	CDD:224054	78/295 (26%)
		ABC_subfamily_A	600..819	CDD:213230	71/229 (31%)
		ABC2_membrane_3	1014..1379	CDD:289468	79/433 (18%)
		ABC2_membrane_4	1154..1348	CDD:289500	44/224 (20%)
		CcmA	1430..1738	CDD:224054
		ABC_subfamily_A	1433..1645	CDD:213230

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R16705
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.940