Protein Alignment Sid and EXOG

DIOPT Version :10

• Sequence 1: NP_651627.1
• Gene: Sid / 43390
• FlyBaseID: FBgn0039593
• Length: 370
• Species: Drosophila melanogaster
• Sequence 2: NP_005098.2
• Gene: EXOG / 9941
• HGNCID: 3347
• Length: 368
• Species: Homo sapiens
• Alignment Length: 306
• Identity: 59/306 - (19%)
• Similarity: 93/306 - (30%)
• Gaps: 124/306 - (40%)

  Fly    98 KVPDTSCSIPSATFAV----GFSFNGRFMELYRNCFDGYSLAFQHSIYKAYRYVNTVPRPNPTWQ 158
            |.||     .||..||    ||...|.....|.|          |::  :|.....|||    |.
Human    51 KQPD-----GSAEKAVLEQFGFPLTGTEARCYTN----------HAL--SYDQAKRVPR----WV 94

  Fly   159 SDQLS-----GGFDNAYEGRATQACLLTNLGAVQPQCKF----------------------DRGH 196
            .:.:|     |..|..:                   |||                      .|||
Human    95 LEHISKSKIMGDADRKH-------------------CKFKPDPNIPPTFSAFNEDYVGSGWSRGH 140

  Fly   197 MTPA-SAFISTELKKSTFRYLNAIPQYRGVNRGKWKAVETWVNNMVRGLYDNPIINN-VQIPRTY 259
            |.|| :...|::....||...|.:||....|.|.|..:|.:...:.....|..:::. :.:|:|
Human   141 MAPAGNNKFSSKAMAETFYLSNIVPQDFDNNSGYWNRIEMYCRELTERFEDVWVVSGPLTLPQT- 204

  Fly   260 DVLKVCIGALGVHRLRHNTNNNMIPIYLLDNNKIPVPEWMYKIV----SHLSGDKWVM------- 313
                            ......::...::..:.:.||..:||::    |.:|.:...:
Human   205 ----------------RGDGKKIVSYQVIGEDNVAVPSHLYKVILARRSSVSTEPLALGAFVVPN 253

  Fly   314 --------LTYNDVSLPNQQALN---------------QICHVIPC 336
                    ||...|||.:.:.|:               .||.|..|
Human   254 EAIGFQPQLTEFQVSLQDLEKLSGLVFFPHLDRTSDIRNICSVDTC 299

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sid	NP_651627.1	Endonuclease_NS	106..358	CDD:460120	56/298 (19%)
EXOG	NP_005098.2	NUC	77..286	CDD:214683	45/260 (17%)
		Exog_C	302..350	CDD:465620