DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sid and CG14120

DIOPT Version :9

Sequence 1:	NP_651627.1	Gene:	Sid / 43390	FlyBaseID:	FBgn0039593	Length:	370	Species:	Drosophila melanogaster
Sequence 2:	NP_648610.1	Gene:	CG14120 / 39463	FlyBaseID:	FBgn0036321	Length:	1371	Species:	Drosophila melanogaster

Alignment Length:	383	Identity:	83/383 - (21%)
Similarity:	140/383 - (36%)	Gaps:	109/383 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    38 LSQNNGVYDIQRSDIVEIHQTLYLLCNGGL----HRTT-----------------------FLCR 75
            |...:|:|.::....:::|      |.|.|    :|.|                       |:|:
  Fly   628 LPDESGLYTVEEGSSIDLH------CTGALVSPFNRYTALSARCVGDQLYEAEGQLVNIRGFVCQ 686

  Fly    76 YDSVFSPALSSAACAPPDPVVVKVPDTSCSIPSATFAVGFSFNGRFMELYRNCFDGYSLAFQHSI 140
            ....::...|..:||....||               .:||.....|:.....|:|...   |.|.
  Fly   687 SWPTYAAVRSGQSCAGGTDVV---------------HIGFDVAAGFLSHVELCYDQQE---QISR 733

  Fly   141 YKAYR-------YVNTVPRPNPTWQSDQLSGG-----FDNAYEGRATQACLLTNLGAVQPQCKFD 193
            |..|.       |...|.:|. ..:.|..||.     :|.:::..|....|  .|.|.|   .||
  Fly   734 YARYELTPANVAYQKGVAQPG-YLRGDFYSGEDVNVLYDQSHQLDAFSTAL--GLDASQ---YFD 792

  Fly   194 --------RGHMTPASAFISTELKKSTFRYLNAIPQYRGVNRGKWKAVETWVNNMVRGLYDNPII 250
                    ||.:.....|:.:..:::|..|:||:||:|.:|.|.|.|||:.:...|.   |..:
  Fly   793 STKDLYLTRGQLAARLDFVHSSAQRATHFYVNAVPQWRSINIGNWLAVESSLKQFVA---DEAL- 853

  Fly   251 NNVQI-PRTYDVLKVCIGALGVHRLRHNTNNNMIPIYL-LDNNKIPVPEWMYKIVSHLSGDKWVM 313
             ||.: ..:||:..:           .|:.....|:|| .:..::||.:.:|:||......|.|:
  Fly   854 -NVSVHAGSYDISTL-----------PNSQGVQTPLYLNAETKQLPVAKILYRIVIDQESRKGVV 906

  Fly   314 L-TYNDVSLPNQQALNQ--ICHVIPCHPGLNLNTKD-------VGHTVCCDPYRFITI 361
            | ..|:..:...:.|..  ||..:    |..::..|       .|::..|....||.:
  Fly   907 LIVVNNPHITLTETLEDYVICEDV----GAQIDWLDWDKANLQKGYSYACSVEDFIEV 960

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sid	NP_651627.1	Endonuclease_NS	106..358	CDD:279553	65/283 (23%)
CG14120	NP_648610.1	NUC	164..416	CDD:238043
		NUC	718..967	CDD:294067	64/272 (24%)
		NUC	1111..1359	CDD:238043
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45450468
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR13966
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940