DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Sid and Exog

DIOPT Version :9

Sequence 1:	NP_651627.1	Gene:	Sid / 43390	FlyBaseID:	FBgn0039593	Length:	370	Species:	Drosophila melanogaster
Sequence 2:	XP_006244150.2	Gene:	Exog / 301062	RGDID:	1304628	Length:	443	Species:	Rattus norvegicus

Alignment Length:	315	Identity:	64/315 - (20%)
Similarity:	100/315 - (31%)	Gaps:	112/315 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 VYLSQNNGVYDIQ--RSDIVEIHQTLYLLCNG--GLHRTTFLCRYDSVFSPALS----------S 86
            |..:||:|...::  ...:.|:.:  :||..|  |..|:    |.|....|..|          :
  Rat    58 VLAAQNHGCKGLRFASQGLAEVSE--WLLGRGCSGRRRS----RADGAAVPPASGRGVREAGEAA 116

  Fly    87 AACAPPDPVVVKVPDTSCSIPSATFAV----GFSFNGRFMELYRNCFDGYSLAFQHSIYKAYRYV 147
            |.|:       .||.|..:..|....|    ||...|.....|.|          |::  :|...
  Rat   117 ARCS-------TVPGTELAFKSVEKVVLEQFGFPLTGTETRRYTN----------HAL--SYDQA 162

  Fly   148 NTVPRPNPTW-----QSDQLSGGFDNAYEGRATQACLLTNLGAVQPQCKF--------------- 192
            ..|||    |     ..|::.|..|..:                   |||
  Rat   163 KRVPR----WVLEHISKDKIIGDADRKH-------------------CKFKPDPTVPSAFSALNE 204

  Fly   193 -------DRGHMTPA-SAFISTELKKSTFRYLNAIPQYRGVNRGKWKAVETWVNNMVRGLYDNPI 249
                   .||||.|| :...|:|....||...|.:||....|.|.|..:|.:...:.....|..|
  Rat   205 DYIGSGWSRGHMAPAGNNKFSSEAMAETFYLSNIVPQNFENNSGYWNRIEMYCRELTERFEDVWI 269

  Fly   250 INN-VQIPRTYDVLKVCIGALGVHRLRHNTNNNMIPIYLLDNNKIPVPEWMYKIV 303
            ::. :.:|.|                 .|.....:...::..:.:.||..:||::
  Rat   270 VSGPLTLPHT-----------------RNDGTKTVSYQVIGEDNVAVPSHLYKVI 307

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sid	NP_651627.1	Endonuclease_NS	106..358	CDD:279553	45/231 (19%)
Exog	XP_006244150.2	NUC	152..361	CDD:214683	40/208 (19%)
Exog	XP_006244150.2	Exog_C	377..425	CDD:407864
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166341978
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D933605at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR13966
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.950