DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10011 and KEG

DIOPT Version :9

Sequence 1:	NP_651624.2	Gene:	CG10011 / 43387	FlyBaseID:	FBgn0039590	Length:	2119	Species:	Drosophila melanogaster
Sequence 2:	NP_196857.2	Gene:	KEG / 831197	AraportID:	AT5G13530	Length:	1625	Species:	Arabidopsis thaliana

Alignment Length:	471	Identity:	122/471 - (25%)
Similarity:	196/471 - (41%)	Gaps:	101/471 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly  1264 LEIEDYNGQTALNIAARNGHLEVVKLLLSFSQPCNDGTGRMKRVDVNHADRDGWTPLRSASWGGH 1328
            ||.::.:||:||::|.|.|..|:|:.:|.:.:           .:|:..|:||..||..|...|.
plant   504 LEAQNADGQSALHLACRRGSAELVEAILEYGE-----------ANVDIVDKDGDPPLVFALAAGS 557

  Fly  1329 SEVVRLLIAQPA-CKIDLADKEGRTALRAAAWSGHEDILKLLIESGADVNSVDRQGRTSLIAASY 1392
            .:.|.:||.:.| .:..|.:..|.:.....::.|..|.::.|:.:|||.|:||.:|.|.|..|..
plant   558 PQCVHVLIKKGANVRSRLREGSGPSVAHVCSYHGQPDCMRELLVAGADPNAVDDEGETVLHRAVA 622

  Fly  1393 MGHYDIVEILLENGANVNHLDLDGRSALCVAALCGSSGYSKVISTLLDHGANTDQLDNDGMSPLL 1457
            ..:.|...::||||.:        ||.....|.|                          ::||.
plant   623 KKYTDCAIVILENGGS--------RSMTVSNAKC--------------------------LTPLH 653

  Fly  1458 VSSFEGNAEVCELLLENAADPDLADFMG-RTPLWAA-CTAGH---------ATVVKLLLFWGCGI 1511
            :.....|..|.:..:|.::..:::..:. .:|:..| |.|..         ..:|::||..|...
plant   654 MCVATWNVAVIKRWVEVSSPEEISQAINIPSPVGTALCMAASIRKDHEKEGRELVQILLAAGADP 718

  Fly  1512 DCMDSE-GRTVLSIGAAQGNVETVRQLLDRGLDETHRDNAGWTPLHYAAFEGFHEVCLQLLESGA 1575
            ...|:: |||.|...|...|||.||.:||.|::...|:.....|||.|...|.:.....|||||:
plant   719 TAQDAQHGRTALHTAAMANNVELVRVILDAGVNANIRNVHNTIPLHMALARGANSCVSLLLESGS 783

  Fly  1576 KIDECDNEGKTALHLAAQEGR-----LHCVQALLDIHSSFVDQKAHDGKTAFRLACLEG------ 1629
            ..:..|:||..|.|:||...:     |..:..:|....:.||.:.|.|||....  ||.
plant   784 DCNIQDDEGDNAFHIAADAAKMIRENLDWLIVMLRSPDAAVDVRNHSGKTVRDF--LEALPREWI 846

  Fly  1630 HMDTVEFLLKFCCDVNSKDADSRTTLYILALENKLEIVKYLLDMTNVDVNIPDSEGRTALHVAAW 1694
            ..|.:|.|||       :......|:|.:.     :.||:...:|            |.||  .|
plant   847 SEDLMEALLK-------RGVHLSPTIYEVG-----DWVKFKRGIT------------TPLH--GW 885

  Fly  1695 QG----HADMVKTLIE 1706
            ||    ....|:|::|
plant   886 QGAKPKSVGFVQTILE 901

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10011	NP_651624.2	AAA	344..457	CDD:214640
		Methylase_S	<772..885	CDD:279728
		Ank_4	1237..1291	CDD:290365	11/26 (42%)
		ANK	1266..1403	CDD:238125	38/137 (28%)
		ANK repeat	1270..1313	CDD:293786	11/42 (26%)
		Ank_2	1275..1380	CDD:289560	28/105 (27%)
		ANK repeat	1315..1347	CDD:293786	11/32 (34%)
		ANK repeat	1349..1380	CDD:293786	8/30 (27%)
		Ank_2	1354..1449	CDD:289560	22/94 (23%)
		ANK repeat	1382..1413	CDD:293786	9/30 (30%)
		ANK	1410..1538	CDD:238125	28/139 (20%)
		ANK repeat	1415..1446	CDD:293786	4/30 (13%)
		Ank_5	1438..1489	CDD:290568	5/51 (10%)
		ANK	1479..1604	CDD:238125	41/141 (29%)
		ANK repeat	1484..1515	CDD:293786	8/41 (20%)
		Ank_2	1489..1581	CDD:289560	32/102 (31%)
		ANK repeat	1517..1548	CDD:293786	13/31 (42%)
		ANK repeat	1550..1581	CDD:293786	10/30 (33%)
		Ank_2	1555..1648	CDD:289560	31/103 (30%)
		ANK	1578..1705	CDD:238125	35/141 (25%)
		ANK repeat	1617..1648	CDD:293786	10/36 (28%)
		Ank_2	1624..1715	CDD:289560	21/93 (23%)
		ANK	1645..1771	CDD:238125	14/66 (21%)
		ANK repeat	1650..1682	CDD:293786	5/31 (16%)
		ANK repeat	1684..1715	CDD:293786	9/27 (33%)
		Ank_2	1689..1781	CDD:289560	8/22 (36%)
		ANK repeat	1717..1742	CDD:293786
		ANK repeat	1750..1775	CDD:293786
KEG	NP_196857.2	RING-HC_ScPSH1_like	9..56	CDD:319482
		RING-HC finger (C3HC4-type)	10..55	CDD:319482
		S_TKc	138..424	CDD:214567
		ANKYR	<427..571	CDD:223738	24/77 (31%)
		ANK repeat	472..508	CDD:293786	2/3 (67%)
		ANK repeat	510..542	CDD:293786	11/42 (26%)
		PHA03095	517..>857	CDD:222980	102/393 (26%)
		ANK repeat	544..575	CDD:293786	10/30 (33%)
		ANK repeat	577..610	CDD:293786	8/32 (25%)
		ANK repeat	688..722	CDD:293786	7/33 (21%)
		ANK repeat	725..756	CDD:293786	13/30 (43%)
		ANK repeat	758..789	CDD:293786	10/30 (33%)
		ANK repeat	791..828	CDD:293786	10/36 (28%)
		SH3_15	909..984	CDD:375773
		SH3_15	1053..1110	CDD:375773
		SH3_15	1116..1166	CDD:375773
		SH3_15	1242..1363	CDD:375773
		SH3_15	1426..1488	CDD:375773
		SH3_15	1560..1617	CDD:375773
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm2422
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.000