back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG10011 and ankrd28b

DIOPT Version :9

Sequence 1:	NP_651624.2	Gene:	CG10011 / 43387	FlyBaseID:	FBgn0039590	Length:	2119	Species:	Drosophila melanogaster
Sequence 2:	XP_009290540.1	Gene:	ankrd28b / 560747	ZFINID:	ZDB-GENE-070622-4	Length:	1052	Species:	Danio rerio

Alignment Length:	1010	Identity:	250/1010 - (24%)
Similarity:	402/1010 - (39%)	Gaps:	259/1010 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly  1213 QDENASSTLH---QLSDSHHIELHKGKALI----HILANDGNHQL--LERALNAC---------K 1259
            ||....:.||   .|.|:..|||     ||    .:.|.| |..|  |.||:.:|         |
Zfish    37 QDNEKRTPLHAAAYLGDAEIIEL-----LILSGARVNAKD-NKWLTPLHRAVASCSEEAVQVLLK 95

  Fly  1260 SPIDLEIEDYNGQTALNIAARNGHLEVVKLLLSFSQPCNDGTGRMKRVDVNHADRDGWTPLRSAS 1324
            ...|:...|.|.||.|::||.|..:...:.|:....            :||.:||.|.|.|..|:
Zfish    96 HSADVNARDKNWQTPLHVAAANKAVRCAEALVPLLS------------NVNVSDRAGRTALHHAA 148

  Fly  1325 WGGHSEVVRLLIAQPACKIDLADKEGRTALRAAAWSGHEDILKLLIESGADVNSVDRQGRTSLIA 1389
            :.||.|:||||:::.| .|:..||:.|.|:..||:.||.:::|||:..||:|...|::..|.|.|
Zfish   149 FSGHLEMVRLLLSRGA-NINAFDKKDRRAIHWAAYMGHMEVVKLLVSHGAEVPCKDKKAYTPLHA 212

  Fly  1390 ASYMGHYDIVEILLENGANVNHLDLDGRSALCVAALCGSSGYSKVISTLLDHGANTDQLDNDGMS 1454
            |:..|...:|:.||:.|.::|..:..|.:.|.||..   :|...|::.|::.|||.:|::..|.:
Zfish   213 AASSGMISVVKYLLDMGVDMNEPNAYGNTPLHVACY---NGQDVVVNELIECGANVNQVNEKGFA 274

  Fly  1455 PLLVSSFEGNAEVC-ELLLENAADPDLADFMGRTPLWAACTAGHATVVKLLLFWGCGIDCMDSEG 1518
            ||..::...:..:| |||:.|.||.::....|:|||......|..:..:.::..|..|||.|..|
Zfish   275 PLHFTAASRHGALCLELLVGNGADVNIKSKDGKTPLHMTAIHGRFSRSQAIIQNGAEIDCEDKNG 339

  Fly  1519 RTVLSIGAAQGNVETVRQLLDRGLDETHRDNAGWTPLHYAAFEGFHEVCLQLLESGAKIDECDNE 1583
            .|.|.|.|..|:...:..|:..|.|...|...|..|||.||..||.:.|.:||.||..||..|:.
Zfish   340 NTPLHIAARYGHELLINTLITNGADTAKRGVHGMFPLHLAALSGFSDCCRKLLSSGFDIDTPDDF 404

  Fly  1584 GKTALHLAAQEGRLHCVQALLDIHSSFVDQKAHDGKTAFRLACLEGHMDTVEFLLKFCCDVN--- 1645
            |:|.||.||..|.|.|:..||:..:.| ::|...|:|....|....:...:..|:....:||
Zfish   405 GRTCLHAAAAGGNLECLNLLLNTGADF-NRKDSFGRTPLHYAAANCNYQCLFALVGSGANVNELD 468

  Fly  1646 -----------SKDADSRTTLYIL--------------------------------ALENKLEIV 1667
                       :.|||.:...|:|                                |.|..|:::
Zfish   469 KRGCTPLHYAAASDADGKCLEYLLRNDANPGIRDNQGYNAVHYASAYGHRLCLELIASETPLDVL 533

  Fly  1668 KYL--LDMTN------------------------------VDVNIPDSEGRTALHVAAWQGHADM 1700
            ...  .|:.|                              :|:::..::|.|.|.:||::||.:.
Zfish   534 METSGTDILNDSDVLAPVSPLHLAAYHGHHQALEVLVQSLLDLDVRTAQGHTPLDLAAFKGHVEC 598

  Fly  1701 VKTLIEAGADVNSMDLE-ARTPLHSCAWQGNHDVMNILL-------------------------- 1738
            |..||..||.:...|.. .|||:|:.|..|:.:.:.:|:
Zfish   599 VDVLINQGASILVKDYTLKRTPIHAAATNGHSECLRLLIGNADLQSAVDIQDGIGQTPLMLSVLG 663

  Fly  1739 -----YY-----GALADHACKQGATALGISAQEGHEKCVIALLQFGAN----------------- 1776
                 .|     ||..|...|.|.|||...|..|||:||.||||..|:
Zfish   664 GHTDCVYSLINKGANVDAKDKWGRTALHRGAVTGHEECVEALLQHSASFMVRDCRGRSPVHLASA 728

  Fly  1777 --------------------PYKSDHCGRTPIKLAAKSSRTSILKIF---ESYTKNEASNPNEPK 1818
                                |..:||.|.||:..|..:...:.:::.   |.:.|.| .||..|
Zfish   729 CGHVGVLGGLLHAAQSVESIPVITDHQGYTPLHWACYNGHDTCVEVLLEQELFHKTE-GNPFSP- 791

  Fly  1819 FHAHASMLRSPDQPPALPLHQNLAPY-----------PAHASASSVCSAATTATVHNGSHLHVLN 1872
              .|.:::...:....| |.:.|:|.           |.||:|.:.........:.:.:.::.::
Zfish   792 --LHCAVINDNEGAVEL-LIETLSPVIVNANDSKNRTPLHAAAFTDHVECLQLLLGHNAQVNCVD 853

  Fly  1873 ASSST---HSSNNFYQNTMQ-------SDTSSLHKRKSVISSQSTGSSNDQAPLTFTQQ------ 1921
            |...|   .::.|...|.::       :|.:.....|:.....:....::.:.|...::
Zfish   854 AGGKTPLMMAAENGQTNAVEVLVSSAKADLTLQDANKNTALHLACSKGHETSALLILEKITDRNL 918

  Fly  1922 -------LQRQSKLSSRNNLMVNSKHASSSGAAGHKSSGGGGGAQRHSQVLPDLSEHQLASNMTN 1979
                   ||....:::||.|.|..:...:.||               |.:..|.:.:..|.....
Zfish   919 INSTNAALQTPLHVAARNGLTVVVQELLAKGA---------------SVLAVDENGYTPALACAP 968

  Fly  1980 EADMYDMECMSPLYAT-PPHSPSSELSSPGQLPGL 2013
            ..|:.|  |::.:.|| .|.||..     |.:|.|
Zfish   969 NKDVAD--CLALILATMMPVSPGG-----GSVPTL 996

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.