DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG10011 and Tnks

DIOPT Version :10

Sequence 1:NP_651624.2 Gene:CG10011 / 43387 FlyBaseID:FBgn0039590 Length:2119 Species:Drosophila melanogaster
Sequence 2:NP_001262963.1 Gene:Tnks / 43095 FlyBaseID:FBgn0027508 Length:1520 Species:Drosophila melanogaster


Alignment Length:942 Identity:235/942 - (24%)
Similarity:358/942 - (38%) Gaps:269/942 - (28%)


- Green bases have known domain annotations that are detailed below.


  Fly  1241 ILANDGNHQLLERALNACK-----------SPIDLEIEDYNGQ--TALNIAARNGHLEVVKLLLS 1292
            ::|||...:|.|    |||           :|..:...|..|:  |.|:.||..|..|||:.|| 
  Fly    18 VMANDPLRELFE----ACKTGEIAKVKKLITPQTVNARDTAGRKSTPLHFAAGYGRREVVEFLL- 77

  Fly  1293 FSQPCNDGTGRMKRVDVNHADRDGWTPLRSASWGGHSEVVRLLI---AQP--------------- 1339
                 |.|      ..:...|..|..||.:....||:||||||:   |.|               
  Fly    78 -----NSG------ASIQACDEGGLHPLHNCCSFGHAEVVRLLLKAGASPNTTDNWNYTPLHEAA 131

  Fly  1340 ------AC-------------------KIDLADKEGRTALRA---------AAWSGHED-ILKLL 1369
                  .|                   .::|||:..|..|..         ||.||.|| :|.||
  Fly   132 SKGKVDVCLALLQHGANHTIRNSEQKTPLELADEATRPVLTGEYRKDELLEAARSGAEDRLLALL 196

  Fly  1370 IESGADVNSVDRQGRTSLIAASYMGHYDIVEILLENGANVNHLDLDGRSALCVAALCGSSGYSKV 1434
            .....:.::.|.:..|.|..|:......||||||.|||:|:..|..|...|..|.   |.|:..|
  Fly   197 TPLNVNCHASDGRRSTPLHLAAGYNRIGIVEILLANGADVHAKDKGGLVPLHNAC---SYGHFDV 258

  Fly  1435 ISTLLDHGANTDQLDNDGMSPLLVSSFEGNAEVCELLLENAADPDLADFMGRTPLWAACT----- 1494
            ...|:..|||.:..|....:||..::.:...|||.|||...|||.|.:...::.:.||.|     
  Fly   259 TKLLIQAGANVNANDLWAFTPLHEAASKSRVEVCSLLLSRGADPTLLNCHSKSAIDAAPTRELRE 323

  Fly  1495 ------AGHATVVKLLLFWGCGID----CMDSEGRTV-------------------LSIGAAQGN 1530
                  .||           |.:|    |..|..:.:                   |::.:..|.
  Fly   324 RIAFEYKGH-----------CLLDACRKCDVSRAKKLVCAEIVNFVHPYTGDTPLHLAVVSPDGK 377

  Fly  1531 VETVRQLLDR-GLDETHRDNAGWTPLHYAAFEGFHEVCLQ-LLESGAKIDECDNEGKTALHLAAQ 1593
            .:.:.:||.| |.....::.|..||||.|| |..|...:: ||:.|||::..|:.|:|.||..|:
  Fly   378 RKQLMELLTRKGSLLNEKNKAFLTPLHLAA-ELLHYDAMEVLLKQGAKVNALDSLGQTPLHRCAR 441

  Fly  1594 EGRLHCVQALLDIHSSFVDQKAHDGKTAFRLA-----------------CLE----GHMDTV-EF 1636
            :.:  .|:.||. :::..:..:.:|.||.:||                 .||    |.:||| ..
  Fly   442 DEQ--AVRLLLS-YAADTNIVSLEGLTAAQLASDSVLKLLKNPPDSETHLLEAAKAGDLDTVRRI 503

  Fly  1637 LLKFCCDVNSKDADSR--TTLYILALENKLEIVKYLLDMTNVDVNIPDSEGRTALHVAAWQGHAD 1699
            :|.....||.:|.|.|  |.|:..|..|::.:|::||: ...:|...|..|...||.|...||.:
  Fly   504 VLNNPISVNCRDLDGRHSTPLHFAAGFNRVPVVQFLLE-HGAEVYAADKGGLVPLHNACSYGHYE 567

  Fly  1700 MVKTLIEAGADVNSMDLEARTPLHSCAWQGNHDVMNILLYYGALADHACKQGATALGISAQEGHE 1764
            :.:.|::.||:||..||...||||..|.:|.:|:..:||.:||......:.|||...:..:..|:
  Fly   568 VTELLVKHGANVNVSDLWKFTPLHEAAAKGKYDICKLLLKHGADPMKKNRDGATPADLVKESDHD 632

  Fly  1765 KCVIALLQFGANPYKSDHCGRTPIKLAAKS---SRTSILKIFESYTKNEASNPNEPKFHAHASM- 1825
              |..||:           |.:.:..|||.   :|...|...||....:|...|....|..|.. 
  Fly   633 --VAELLR-----------GPSALLDAAKKGNLARVQRLVTPESINCRDAQGRNSTPLHLAAGYN 684

  Fly  1826 --------------LRSPDQPPALPLHQNLAPY-------------------------PAHASAS 1851
                          :.:.|:...:||| |.:.|                         |.|.:|.
  Fly   685 NFECAEYLLENGADVNAQDKGGLIPLH-NASSYGHLDIAALLIKHKTVVNATDKWGFTPLHEAAQ 748

  Fly  1852 SVCSAATTATVHNGSHLHVLNASSST----------------HSSNNFYQNTMQSDTSSLHKRK- 1899
            ...:...:..:.:|:..::.|....|                ..:.:..|..:.:.|.||.... 
  Fly   749 KGRTQLCSLLLAHGADAYMKNQEGQTPIELATADDVKCLLQDAMATSLSQQALSASTQSLTSSSP 813

  Fly  1900 ----SVISSQSTGSSNDQA---PLTFTQQLQRQSK----------LSSRNNLMVNSKHASSSGAA 1947
                :..::..|.||:..|   |.|.|..|...:.          |||...:         |.|.
  Fly   814 APDATAAAAPGTSSSSSSAILSPTTETVLLPTGASMILSVPVPLPLSSSTRI---------SPAQ 869

  Fly  1948 GHKSSGGGGGAQRHSQVLPDLSEHQLASNMTN 1979
            |.:::|..|.:.  ..:|||      |..:||
  Fly   870 GAEANGAEGSSS--DDLLPD------ADTITN 893

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG10011NP_651624.2 ANKYR 1236..1489 CDD:440430 90/313 (29%)
ANK repeat 1270..1313 CDD:293786 13/44 (30%)
ANK repeat 1315..1347 CDD:293786 15/74 (20%)
ANK repeat 1349..1380 CDD:293786 11/40 (28%)
ANK repeat 1382..1413 CDD:293786 13/30 (43%)
ANK repeat 1415..1446 CDD:293786 10/30 (33%)
ANKYR 1469..1788 CDD:440430 103/378 (27%)
ANK repeat 1484..1515 CDD:293786 8/45 (18%)
ANK repeat 1517..1548 CDD:293786 6/50 (12%)
ANK repeat 1550..1581 CDD:293786 14/31 (45%)
ANK repeat 1617..1648 CDD:293786 14/52 (27%)
ANK repeat 1650..1682 CDD:293786 10/33 (30%)
ANK repeat 1684..1715 CDD:293786 11/30 (37%)
ANK repeat 1717..1742 CDD:293786 9/24 (38%)
ANK repeat 1750..1775 CDD:293786 7/24 (29%)
TnksNP_001262963.1 ANKYR 9..330 CDD:440430 93/330 (28%)
ANK repeat 59..87 CDD:293786 12/39 (31%)
ANK repeat 89..120 CDD:293786 13/30 (43%)
ANK repeat 122..153 CDD:293786 1/30 (3%)
ANK repeat 212..240 CDD:293786 13/27 (48%)
ANK repeat 242..273 CDD:293786 10/33 (30%)
ANK repeat 275..306 CDD:293786 12/30 (40%)
ANKYR 334..623 CDD:440430 85/293 (29%)
ANK repeat 363..396 CDD:293786 6/32 (19%)
ANK repeat 398..429 CDD:293786 14/31 (45%)
ANK repeat 431..459 CDD:293786 8/30 (27%)
ANKYR 469..783 CDD:440430 78/328 (24%)
ANK repeat 483..515 CDD:293786 9/31 (29%)
ANK repeat 522..550 CDD:293786 8/28 (29%)
ANK repeat 552..583 CDD:293786 11/30 (37%)
ANK repeat 585..610 CDD:293786 9/24 (38%)
ANK repeat 638..668 CDD:293786 8/40 (20%)
ANK repeat 672..703 CDD:293786 3/30 (10%)
ANK repeat 705..736 CDD:293786 5/31 (16%)
ANK repeat 738..769 CDD:293786 4/30 (13%)
SAM_tankyrase1,2 887..952 CDD:188923 4/13 (31%)
tankyrase_like 948..1170 CDD:238718
Blue background indicates that the domain is not in the aligned region.

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