DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG10011 and trpn1

DIOPT Version :9

Sequence 1:NP_651624.2 Gene:CG10011 / 43387 FlyBaseID:FBgn0039590 Length:2119 Species:Drosophila melanogaster
Sequence 2:NP_899192.1 Gene:trpn1 / 368273 ZFINID:ZDB-GENE-030728-7 Length:1614 Species:Danio rerio


Alignment Length:1017 Identity:259/1017 - (25%)
Similarity:389/1017 - (38%) Gaps:304/1017 - (29%)


- Green bases have known domain annotations that are detailed below.


  Fly  1059 YLTSRHV-DLDLILMLLESRLNLSDCFYTNQMNCCAQCEHDFKYDVNFLPKTRAM------LERF 1116
            |..||.. .|.::..||  :.:..|...|...|.|             ||...|.      :.|.
Zfish   120 YAASRSTGGLAVVQTLL--KFSSKDARLTPDKNGC-------------LPLLLAAEAGNVGIVRE 169

  Fly  1117 LASELSEP-----------FAQFLCDFFKPSLPTDAKMLKLLIETGINNAESQNS---------- 1160
            |.|..|||           .|..:|     ....|.:|.|:|:|.|. |.:|||.          
Zfish   170 LLSSQSEPQIRAAKTANGDTALHIC-----CRRRDVEMAKILVEFGA-NPDSQNDEGQTPLHIAA 228

  Fly  1161 -------------CESSLMSPELSEKSQNIDFELA---------DLLLSSEKSCLMETQRAGS-- 1201
                         |::   :..:|:|.......:|         ::|....:||::...:.|:  
Zfish   229 HEGDENMLKFLYLCKA---NANISDKMDRSPLHIAAERGHTNVVEILTEKFRSCVLARTKDGNTL 290

  Fly  1202 ---PSEHSEP-----------PAESQDENASSTLHQLSDSHHIELHK---------------GKA 1237
               .|:...|           |....:::.:..||..:...|..:.|               |:.
Zfish   291 LHIASQCGHPTTALSFLRKGVPLHMPNKSGAVCLHAAAKRGHTAVVKALLQKGAHVDAAARDGQT 355

  Fly  1238 LIHI------------LANDGNHQLL-------------------ERALN-ACKSPIDLEIEDYN 1270
            .:||            |...|.|..|                   |||.. ..||..::..|..|
Zfish   356 ALHIAVENCRPQVVQMLLGFGAHVQLRGGKAQETPLHISARVKEGERAAEMLLKSGAEVNAEQEN 420

  Fly  1271 GQTALNIAARNG---------------------------------HLEVVKLLLSF--------- 1293
            |:|||::|||:|                                 |..||:.:|:|         
Zfish   421 GETALHVAARHGSLQMIRALIQEGGDPRWRSRVGESPLHVAVRHCHAHVVQEILTFLTNEKSRRD 485

  Fly  1294 SQPC-----NDGTGRMK-----RVDVNH----------------AD------RDGWTPLRSASWG 1326
            ::.|     .||...:.     |.|..|                ||      :.|.|||..::..
Zfish   486 AELCVCEGNQDGETALHLAAELRTDALHQPEEDITIIQILMEHQADITAVTRQTGETPLHYSARV 550

  Fly  1327 GHSEVVRLLIAQ-PACKIDLA----DKEGRTALRAAAWSGHEDILKLLIESGADVNSVDRQGRTS 1386
            |::.|::.::.. |..:|..|    .|.|.:.|..||..||.:::|:|:::.|.|:..|.:|:.:
Zfish   551 GNTAVLQEMLRNVPTNQIQTAINKHSKNGWSPLLLAADQGHTEVVKILLQNNARVDVFDEEGKAA 615

  Fly  1387 LIAASYMGHYDIVEILLENGANVNHLDLDGRSALCVAALCGSSGYSKVISTLLD-HGANTDQLDN 1450
            :..|:..||.|||::||...|.||.....|.:.|.::|   .:|.::::..|:: |.|:.|.|..
Zfish   616 IHLAAQRGHQDIVDVLLSQKAFVNAKTKQGLTPLHLSA---QNGSARLVRLLVENHQASVDALSL 677

  Fly  1451 DGMSPLLVSSFEGNAEVCELLLENAADPDLADFMGRTPLWAACTAGHATVVKLLLFWGCGIDCMD 1515
            ...:||.:::..|..:||..||...||....|..|:|||..|..:.|:.||||.|.....:..:.
Zfish   678 RKQTPLHLAAMSGQLDVCSSLLNLRADITATDSRGQTPLHLAAESDHSEVVKLFLRLRPELSTLA 742

  Fly  1516 SE-GRTVLSIGAAQGNVETVRQLL---DRGLDETHRDNAGWTPLHYAAFEGFHEVCLQLLESGAK 1576
            :| |.|...|.||:|:|..:|:||   ..|:...:....|..|||.||..|..||...|||:||.
Zfish   743 NEDGSTCTHIAAAKGSVSVIRELLMFNQGGVGTLNHKAHGLCPLHLAAAGGHAEVVKVLLEAGAS 807

  Fly  1577 IDECDNEGKTALHLAAQEGRLHCVQAL-----LDIHSS-----------------FV-------- 1611
            :.|.|.||.||:||||:.|..|.::.|     |.|.||                 ||        
Zfish   808 VTEEDAEGMTAVHLAAKHGHTHILEVLRGSVPLKIQSSKTGFTALHVAASFGQMNFVREILTKVP 872

  Fly  1612 --------------DQK-----AHDGKTAFRLACLEGHMDTVEFLLKFCCDVNSKDADSR----T 1653
                          |.|     |..|.|...||...||...|..||.  |.....||::.    :
Zfish   873 ATIRSEFPTISGKDDIKRQQPLAESGFTPLHLASQSGHESVVRLLLN--CPGVQADAETNIQGSS 935

  Fly  1654 TLYILALENKLEIVKYLLDMTNVDVNIPDSEGRTALHVAAWQGHADMVKTLIEAGADVNSMDLEA 1718
            .|::.|......:|..||..::..::..|..||:|||:||..||.|||:.|:..||::|..|:..
Zfish   936 PLHLAAQSGHTAVVGLLLSRSSSLLHQADRRGRSALHLAAAHGHVDMVRVLLGQGAEINHTDMSG 1000

  Fly  1719 RTPLHSCAWQGNHDVMNILLYYGALADHACKQGATALGISAQEGHEKCVIALLQFGANPYK--SD 1781
            .|.||..|..|..:|:..|:..||.|...|..|.|.|..:||:.||..||.||:...|..:  .|
Zfish  1001 WTALHYAAEAGCLEVLLFLVESGASACAECHGGRTPLQYAAQQNHESAVIFLLRREKNTLRLLDD 1065

  Fly  1782 H--------CGR---------------TPIKLAAKSSRTSIL 1800
            .        |||               .|:..|.:.||...|
Zfish  1066 KKFIFNLMVCGRMNDNLSLEELVLHTSAPLDTAVRLSRALTL 1107

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG10011NP_651624.2 AAA 344..457 CDD:214640
Methylase_S <772..885 CDD:279728
Ank_4 1237..1291 CDD:290365 24/118 (20%)
ANK 1266..1403 CDD:238125 51/215 (24%)
ANK repeat 1270..1313 CDD:293786 20/110 (18%)
Ank_2 1275..1380 CDD:289560 38/183 (21%)
ANK repeat 1315..1347 CDD:293786 9/36 (25%)
ANK repeat 1349..1380 CDD:293786 10/30 (33%)
Ank_2 1354..1449 CDD:289560 30/95 (32%)
ANK repeat 1382..1413 CDD:293786 12/30 (40%)
ANK 1410..1538 CDD:238125 40/129 (31%)
ANK repeat 1415..1446 CDD:293786 7/31 (23%)
Ank_5 1438..1489 CDD:290568 17/51 (33%)
ANK 1479..1604 CDD:238125 51/133 (38%)
ANK repeat 1484..1515 CDD:293786 11/30 (37%)
Ank_2 1489..1581 CDD:289560 35/95 (37%)
ANK repeat 1517..1548 CDD:293786 12/34 (35%)
ANK repeat 1550..1581 CDD:293786 15/30 (50%)
Ank_2 1555..1648 CDD:289560 44/141 (31%)
ANK 1578..1705 CDD:238125 52/179 (29%)
ANK repeat 1617..1648 CDD:293786 10/30 (33%)
Ank_2 1624..1715 CDD:289560 32/94 (34%)
ANK 1645..1771 CDD:238125 45/129 (35%)
ANK repeat 1650..1682 CDD:293786 5/35 (14%)
ANK repeat 1684..1715 CDD:293786 16/30 (53%)
Ank_2 1689..1781 CDD:289560 37/93 (40%)
ANK repeat 1717..1742 CDD:293786 7/24 (29%)
ANK repeat 1750..1775 CDD:293786 11/24 (46%)
trpn1NP_899192.1 ANK repeat 47..78 CDD:293786
Ank_4 48..101 CDD:290365
ANK 77..239 CDD:238125 31/139 (22%)
ANK repeat 80..111 CDD:293786
ANK repeat 113..148 CDD:293786 8/29 (28%)
ANK repeat 150..184 CDD:293786 11/46 (24%)
Ank_2 155..250 CDD:289560 20/103 (19%)
ANK 182..300 CDD:238125 21/126 (17%)
ANK repeat 186..217 CDD:293786 10/36 (28%)
ANK repeat 219..250 CDD:293786 1/33 (3%)
ANK 247..373 CDD:238125 17/125 (14%)
Ank_4 254..300 CDD:290365 6/45 (13%)
ANK repeat 286..317 CDD:293786 4/30 (13%)
Ank_2 291..382 CDD:289560 13/90 (14%)
ANK repeat 319..350 CDD:293786 4/30 (13%)
ANK 347..474 CDD:238125 25/126 (20%)
ANK repeat 352..382 CDD:293786 6/29 (21%)
Ank_4 389..441 CDD:290365 15/51 (29%)
ANK repeat 420..450 CDD:293786 9/29 (31%)
Ank_2 425..535 CDD:289560 18/109 (17%)
ANK repeat 496..536 CDD:293786 7/39 (18%)
ANK 539..665 CDD:238125 37/128 (29%)
ANK repeat 540..576 CDD:293786 9/35 (26%)
Ank_2 544..641 CDD:289560 30/96 (31%)
ANK repeat 578..609 CDD:293786 10/30 (33%)
ANK 606..732 CDD:238125 42/128 (33%)
ANK repeat 611..642 CDD:293786 12/30 (40%)
Ank_2 616..709 CDD:289560 29/95 (31%)
ANK repeat 644..674 CDD:293786 7/32 (22%)
ANK repeat 678..709 CDD:293786 9/30 (30%)
Ank_2 683..812 CDD:289560 47/128 (37%)
ANK repeat 745..812 CDD:293786 26/66 (39%)
ANK repeat 749..780 CDD:293786 9/30 (30%)
ANK 781..918 CDD:238125 43/136 (32%)
Ank_4 815..865 CDD:290365 15/49 (31%)
ANK repeat 847..895 CDD:293786 4/47 (9%)
ANK 896..1053 CDD:238125 55/158 (35%)
ANK repeat 897..964 CDD:293786 17/68 (25%)
Ank_2 902..997 CDD:289560 32/96 (33%)
ANK repeat 966..997 CDD:293786 16/30 (53%)
Ank_2 971..1058 CDD:289560 36/86 (42%)
ANK repeat 999..1030 CDD:293786 10/30 (33%)
Ion_trans <1342..1480 CDD:278921
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D1115202at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
11.010

Return to query results.
Submit another query.