DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG10011 and ANKRD42

DIOPT Version :9

Sequence 1:NP_651624.2 Gene:CG10011 / 43387 FlyBaseID:FBgn0039590 Length:2119 Species:Drosophila melanogaster
Sequence 2:NP_001287904.1 Gene:ANKRD42 / 338699 HGNCID:26752 Length:527 Species:Homo sapiens


Alignment Length:398 Identity:102/398 - (25%)
Similarity:162/398 - (40%) Gaps:80/398 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly  1429 SGYSKVISTLLDHGANTDQLD-NDGMSPLLVSSFEGNAEVCELLLENAADPDLADFMGRTPLWAA 1492
            :|..|.:|.::..||:.::|| ....:||..::..|:.|....||.:.||.......|.|....|
Human    36 AGDVKQLSEIVVRGASINELDVLHKFTPLHWAAHSGSLECLHWLLWHGADITHVTTRGWTASHIA 100

  Fly  1493 CTAGHATVVKLLLFWGCGIDCMDSEGRTVLSIGAAQGNVETVRQLLDRGLDETHRDNAGWTPLHY 1557
            ...|....|:.|:..|..:...|..|.|.|.:.|..|:..|::.:|..|:|.:..|...|.|:||
Human   101 AIRGQDACVQALIMNGANLTAQDDRGCTPLHLAATHGHSFTLQIMLRSGVDPSVTDKREWRPVHY 165

  Fly  1558 AAFEGFHEVCLQLL-ESGAKIDECDNEGKTALHLAAQEGRLHCVQALLDIHSS-------FVDQK 1614
            |||.| ...||||| :.|..|::.|..|...:||||.||.|||.:.|:...||       |.|  
Human   166 AAFHG-RLGCLQLLVKWGCSIEDVDYNGNLPVHLAAMEGHLHCFKFLVSRMSSATQVLKAFND-- 227

  Fly  1615 AHDGKTAFRLACLEGHMDTVEFLLKFCCDVNSKDADSRTTLYILALENKLEIVKYLLDMTNVDVN 1679
              :|:....||......:.::|:..  .:...||.:.:.||....                    
Human   228 --NGENVLDLAQRFFKQNILQFIQG--AEYEGKDLEDQETLAFPG-------------------- 268

  Fly  1680 IPDSEGRTALHVAAWQGHADMVKTLIEAGA-DVNSMDLEARTPLHSCAWQGNHDVMNILLYYGAL 1743
                      ||||::|...|:|.|:|.|. ::|.......||:|..|.|               
Human   269 ----------HVAAFKGDLGMLKKLVEDGVININERADNGSTPMHKAAGQ--------------- 308

  Fly  1744 ADHACKQGATALGISAQEGHEKCVIALLQFGANPYKSDHCGRTPIKLAAKSSRTSILKIFESYTK 1808
                              ||.:|:..|::.||:...::..|..|..:|.:.:..:.:|:.|...|
Human   309 ------------------GHIECLQWLIKMGADSNITNKAGERPSDVAKRFAHLAAVKLLEELQK 355

  Fly  1809 NEASNPNE 1816
            .:..:.||
Human   356 YDIDDENE 363

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG10011NP_651624.2 AAA 344..457 CDD:214640
Methylase_S <772..885 CDD:279728
Ank_4 1237..1291 CDD:290365
ANK 1266..1403 CDD:238125
ANK repeat 1270..1313 CDD:293786
Ank_2 1275..1380 CDD:289560
ANK repeat 1315..1347 CDD:293786
ANK repeat 1349..1380 CDD:293786
Ank_2 1354..1449 CDD:289560 5/19 (26%)
ANK repeat 1382..1413 CDD:293786
ANK 1410..1538 CDD:238125 29/109 (27%)
ANK repeat 1415..1446 CDD:293786 5/16 (31%)
Ank_5 1438..1489 CDD:290568 14/51 (27%)
ANK 1479..1604 CDD:238125 44/125 (35%)
ANK repeat 1484..1515 CDD:293786 7/30 (23%)
Ank_2 1489..1581 CDD:289560 31/92 (34%)
ANK repeat 1517..1548 CDD:293786 9/30 (30%)
ANK repeat 1550..1581 CDD:293786 15/31 (48%)
Ank_2 1555..1648 CDD:289560 33/100 (33%)
ANK 1578..1705 CDD:238125 31/133 (23%)
ANK repeat 1617..1648 CDD:293786 4/30 (13%)
Ank_2 1624..1715 CDD:289560 18/91 (20%)
ANK 1645..1771 CDD:238125 23/126 (18%)
ANK repeat 1650..1682 CDD:293786 2/31 (6%)
ANK repeat 1684..1715 CDD:293786 11/31 (35%)
Ank_2 1689..1781 CDD:289560 22/92 (24%)
ANK repeat 1717..1742 CDD:293786 5/24 (21%)
ANK repeat 1750..1775 CDD:293786 4/24 (17%)
ANKRD42NP_001287904.1 ANK <17..80 CDD:238125 11/43 (26%)
Ank_4 26..80 CDD:290365 11/43 (26%)
ANK repeat 30..56 CDD:293786 5/19 (26%)
ANK 59..179 CDD:238125 38/120 (32%)
ANK repeat 59..90 CDD:293786 8/30 (27%)
Ank_2 64..156 CDD:289560 24/91 (26%)
ANK repeat 92..123 CDD:293786 7/30 (23%)
ANKYR 94..375 CDD:223738 86/340 (25%)
ANK 121..248 CDD:238125 45/131 (34%)
ANK repeat 125..156 CDD:293786 9/30 (30%)
ANK repeat 158..189 CDD:293786 15/31 (48%)
ANK 188..350 CDD:238125 50/230 (22%)
ANK repeat 297..328 CDD:293786 11/63 (17%)
Prefoldin <394..482 CDD:298833
HalX <430..472 CDD:285826
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D1115202at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
11.010

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