DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG10011 and mlt-2

DIOPT Version :9

Sequence 1:NP_651624.2 Gene:CG10011 / 43387 FlyBaseID:FBgn0039590 Length:2119 Species:Drosophila melanogaster
Sequence 2:NP_492036.2 Gene:mlt-2 / 172459 WormBaseID:WBGene00007252 Length:668 Species:Caenorhabditis elegans


Alignment Length:397 Identity:97/397 - (24%)
Similarity:167/397 - (42%) Gaps:89/397 - (22%)


- Green bases have known domain annotations that are detailed below.


  Fly  1372 SGADVNSVDRQG--RTSLIAASYMGHYDIVE-ILLENGANVNHLDLDGRSALCVAALCGSSGYSK 1433
            |||..:.:|.:.  :...:.|::.|..|.:: :|.:...:::.:|.|..:||.:||..|:   :|
 Worm     2 SGAAADGIDDRDIPKQEFLDAAFNGDIDKIDGLLRDKKVHIDSVDDDQVTALHIAAAMGN---NK 63

  Fly  1434 VISTLLDHGANTDQLDNDGMSPLLVSSFEGNAEVCELLLENAADPDLADFMGRTPLWAACTAGHA 1498
            ::..|||:|||...:::.||:....::.||...|.:.|::..|..:....:|.|.|..||..|||
 Worm    64 LVVRLLDYGANIHAVNHLGMTAYHYAAREGKLAVLDTLMQRGASKNQTTALGVTALTLACAGGHA 128

  Fly  1499 TVVKLLLFWGCGIDCMDSEGRTVLSIGAAQGNVETVRQLLDRGLDETHRDNAGW--TPLHYAAFE 1561
            .||:.|:                                  |..:||.|.....  |||..|...
 Worm   129 DVVRRLI----------------------------------RISNETPRSKQSLAPTPLIVATCS 159

  Fly  1562 GFHEVCLQLLESGAKIDE-CDNEGK-TALHLA--AQEGRLHCVQALLDIHSSFVDQKAHDGKTAF 1622
            ...::|..|.:....:|| ..|.|. |||.:|  ...| ::.|:.|:|:.:| |::|....|||.
 Worm   160 KSPQICSYLADFRVNLDESMKNLGNLTALSMAIVCTPG-VYMVRTLIDLGAS-VNKKGLGDKTAE 222

  Fly  1623 RLACLEGHMDTVEFLLKFCCDVNSK---------DADSRTTL---YILALE-------------- 1661
            .||.:....|.:.|.       |.|         |:|.|..:   :|:..|              
 Worm   223 ELAIMLNRKDLIHFF-------NEKKSYRSRMNADSDVRKEIKNDHIIERELGAPAQNGVSPLMY 280

  Fly  1662 ----NKLEIVKYLLDMTNVDVNIPDSEGRTALHVAAWQGHADMVKTLIEAGADVNSMDLEARTP- 1721
                ..:...|:|:...:.|||:.|:...|:|.:|:.....|::..|::..|||..::....|. 
 Worm   281 ATTVRSINSAKHLVLHRDSDVNMRDNLHITSLQIASLLRVDDIIPLLLQRRADVTVVNKYGSTAY 345

  Fly  1722 ---LHSC 1725
               |.||
 Worm   346 DLFLLSC 352

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG10011NP_651624.2 AAA 344..457 CDD:214640
Methylase_S <772..885 CDD:279728
Ank_4 1237..1291 CDD:290365
ANK 1266..1403 CDD:238125 7/33 (21%)
ANK repeat 1270..1313 CDD:293786
Ank_2 1275..1380 CDD:289560 3/7 (43%)
ANK repeat 1315..1347 CDD:293786
ANK repeat 1349..1380 CDD:293786 3/7 (43%)
Ank_2 1354..1449 CDD:289560 22/79 (28%)
ANK repeat 1382..1413 CDD:293786 4/33 (12%)
ANK 1410..1538 CDD:238125 32/127 (25%)
ANK repeat 1415..1446 CDD:293786 13/30 (43%)
Ank_5 1438..1489 CDD:290568 15/50 (30%)
ANK 1479..1604 CDD:238125 31/130 (24%)
ANK repeat 1484..1515 CDD:293786 11/30 (37%)
Ank_2 1489..1581 CDD:289560 21/94 (22%)
ANK repeat 1517..1548 CDD:293786 3/30 (10%)
ANK repeat 1550..1581 CDD:293786 8/33 (24%)
Ank_2 1555..1648 CDD:289560 28/105 (27%)
ANK 1578..1705 CDD:238125 39/160 (24%)
ANK repeat 1617..1648 CDD:293786 9/39 (23%)
Ank_2 1624..1715 CDD:289560 25/120 (21%)
ANK 1645..1771 CDD:238125 25/115 (22%)
ANK repeat 1650..1682 CDD:293786 9/52 (17%)
ANK repeat 1684..1715 CDD:293786 8/30 (27%)
Ank_2 1689..1781 CDD:289560 11/41 (27%)
ANK repeat 1717..1742 CDD:293786 4/13 (31%)
ANK repeat 1750..1775 CDD:293786
mlt-2NP_492036.2 PHA02876 <9..>214 CDD:165207 61/243 (25%)
ANK repeat 51..79 CDD:293786 12/30 (40%)
Ank_2 53..135 CDD:372319 28/84 (33%)
ANK repeat 81..112 CDD:293786 7/30 (23%)
ANK repeat 144..179 CDD:293786 8/34 (24%)
ANK repeat 181..214 CDD:293786 12/34 (35%)
PHA03095 201..>351 CDD:222980 36/157 (23%)
ANK repeat 273..305 CDD:293786 5/31 (16%)
ANK repeat 307..338 CDD:293786 8/30 (27%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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