DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Hrb98DE and NAM8

DIOPT Version :9

Sequence 1:	NP_524543.1	Gene:	Hrb98DE / 43385	FlyBaseID:	FBgn0001215	Length:	365	Species:	Drosophila melanogaster
Sequence 2:	NP_011954.1	Gene:	NAM8 / 856486	SGDID:	S000001128	Length:	523	Species:	Saccharomyces cerevisiae

Alignment Length:	255	Identity:	57/255 - (22%)
Similarity:	102/255 - (40%)	Gaps:	53/255 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 KLFIGGLDYRTTDENL---------KAHFE---KWGNIVDVVVMKDPRTKRSRGFGFITYSHSSM 84
            :|::|.|| .|.|:|.         :|:..   .|.|.::.........|.::|:.|:.:..|:.
Yeast    55 QLYMGDLD-PTWDKNTVRQIWASLGEANINVRMMWNNTLNNGSRSSMGPKNNQGYCFVDFPSSTH 118

  Fly    85 IDEAQKSRPHKIDGRVVEPKRAVPRQDI----------DSPNAGATVK-----KLFVGALKDDHD 134
            ...|...     :|.:: |.  .|.:.:          :|.|:...||     .:|||.|..:..
Yeast   119 AANALLK-----NGMLI-PN--FPNKKLKLNWATSSYSNSNNSLNNVKSGNNCSIFVGDLAPNVT 175

  Fly   135 EQSIRDYF-QHFGNIVDINIVIDKETGKKRGFAFVEFDDYDPVDKVVLQKQHQ-LNGKMVDVKKA 197
            |..:.:.| ..:.:.....||.|:.||..:|:.||:|.:.|.....:.:.|.. |||:.:   |.
Yeast   176 ESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQQLALSEMQGVFLNGRAI---KV 237

  Fly   198 LPKQNDQQGGGGGRGGPGGRAGGNRGNMGGGNYGNQNGGGNWNNGGNNWGNNRGGNDNWG 257
            .|....||          ..:|.|..|....:..|:|....:.:.|.::.:|  ||:|.|
Yeast   238 GPTSGQQQ----------HVSGNNDYNRSSSSLNNENVDSRFLSKGQSFLSN--GNNNMG 285

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hrb98DE	NP_524543.1	RRM1_hnRNPA_like	32..109	CDD:241022	17/88 (19%)
Hrb98DE	NP_524543.1	RRM_SF	123..195	CDD:302621	20/73 (27%)
NAM8	NP_011954.1	RRM1_NGR1_NAM8_like	55..144	CDD:410023	18/97 (19%)
		RRM2_SECp43_like	162..241	CDD:409781	22/81 (27%)
		RRM3_NGR1_NAM8_like	312..383	CDD:409782
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910