DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Hrb98DE and hnrnpdl

DIOPT Version :9

Sequence 1:	NP_524543.1	Gene:	Hrb98DE / 43385	FlyBaseID:	FBgn0001215	Length:	365	Species:	Drosophila melanogaster
Sequence 2:	NP_001011015.1	Gene:	hnrnpdl / 496424	XenbaseID:	XB-GENE-495016	Length:	297	Species:	Xenopus tropicalis

Alignment Length:	341	Identity:	114/341 - (33%)
Similarity:	167/341 - (48%)	Gaps:	64/341 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 NSNQNQNGNSNGHDDDFPQDSITEPEHMRKLFIGGLDYRTTDENLKAHFEKWGNIVDVVVMKDPR 67
            |.....|.:.|..|:.             |:|||||.:.|:.::|..:..::|.:||..:..||.
Frog    11 NEGSKINASKNQQDEG-------------KMFIGGLSWDTSKKDLTEYLSRFGEVVDCTIKTDPV 62

  Fly    68 TKRSRGFGFITYSHSSMIDEAQKSRPHKIDGRVVEPKRAVPRQDIDSPNAGATVKKLFVGALKDD 132
            |.|||||||:.:..:..:|:..:::.||:||::::||||...:..:.|      ||:|||.|..:
Frog    63 TGRSRGFGFVLFKDAVSVDKVLETKEHKLDGKLIDPKRAKALKGKEPP------KKVFVGGLSPE 121

  Fly   133 HDEQSIRDYFQHFGNIVDINIVIDKETGKKRGFAFVEFDDYDPVDKVVLQKQHQLNGKMVDVKKA 197
            ..|:.|:.||..||.|.:|.:.:|.:|.::|||.||.:...:||.|::..:.||:.....::|.|
Frog   122 TTEEQIKQYFGGFGEIENIELPMDTKTNERRGFCFVTYTGEEPVKKLLESRFHQIGTGKCEIKVA 186

  Fly   198 LPK-------QNDQQGGGG---GRGGPGGRAGGNRGNMGGGNYGNQNGGGNWNNGGNNWGNNRGG 252
            .||       |..|:||.|   ||||..||..|...|.|..||.:||.|        ::|||...
Frog   187 QPKEVYRQQQQKQQKGGRGAATGRGGARGRGRGQGWNQGYSNYYDQNYG--------SYGNNGSY 243

  Fly   253 NDNWGNNSFGGGGGGGGGYGGGNNSWGNNNPWDNGNGGGNFGGGGNNWNNGGNDFGGYQQNYGGG 317
            .|...|||:.|....|..||    |:|                    :|.|..|:.|.|..|  |
Frog   244 ADQGYNNSYSGYDYSGYNYG----SYG--------------------YNQGYTDYSGQQSTY--G 282

  Fly   318 PQRGGGNFNNNRMQPY 333
            ..|||||..|| .|||
Frog   283 KARGGGNHQNN-YQPY 297

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hrb98DE	NP_524543.1	RRM1_hnRNPA_like	32..109	CDD:241022	30/76 (39%)
Hrb98DE	NP_524543.1	RRM_SF	123..195	CDD:302621	25/71 (35%)
hnrnpdl	NP_001011015.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..21		2/9 (22%)
		RRM1_hnRPDL	27..102	CDD:410152	29/74 (39%)
		RRM2_hnRPDL	112..186	CDD:409998	26/73 (36%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	192..224		12/31 (39%)
		Trnau1ap	222..>278	CDD:407550	24/87 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910