DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Hrb98DE and CG3335

DIOPT Version :9

Sequence 1:	NP_524543.1	Gene:	Hrb98DE / 43385	FlyBaseID:	FBgn0001215	Length:	365	Species:	Drosophila melanogaster
Sequence 2:	NP_648337.1	Gene:	CG3335 / 39119	FlyBaseID:	FBgn0036018	Length:	918	Species:	Drosophila melanogaster

Alignment Length:	176	Identity:	55/176 - (31%)
Similarity:	86/176 - (48%)	Gaps:	25/176 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 DDDFPQDSITEPEHMRKLFIGGLDYRTTDENLKAHFEKWGNIVDVVVMK-----DPRTKRSRGFG 75
            :|...:|:..|||....||:..|:::|..|.::.||...|:|..|.:.|     :||..:|.|:|
  Fly   664 EDSRAEDADDEPEPNTTLFLRNLNFKTVQETVEKHFRHLGSIHTVEIAKRRDPENPREFKSLGYG 728

  Fly    76 FITYSHSSMIDEAQKS-RPHKIDGRVVEPKRA---VPRQDIDSPNAGA----------TVKKLFV 126
            ||.:..||:.:.|.|: :...|||..||.||:   :..||    |.||          |..|:.|
  Fly   729 FIQFKKSSVAEHALKNLQLTHIDGNPVELKRSDRVLKTQD----NDGAQRRLASQKKQTGTKILV 789

  Fly   127 GALKDDHDEQSIRDYFQHFGNIVDINIVIDKETGK--KRGFAFVEF 170
            ..:......:.:||.|:.||.:..:.|.....||:  .|||.||::
  Fly   790 RNIPFQAQYREVRDIFKAFGELRSLRIPKKATTGEDAHRGFGFVDY 835

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hrb98DE	NP_524543.1	RRM1_hnRNPA_like	32..109	CDD:241022	29/85 (34%)
Hrb98DE	NP_524543.1	RRM_SF	123..195	CDD:302621	15/50 (30%)
CG3335	NP_648337.1	RRM1_RBM19	2..77	CDD:241008
		RRM_SF	250..314	CDD:302621
		RRM3_RBM19	362..440	CDD:241011
		RRM4_RBM19	552..623	CDD:241013
		RRM	<638..845	CDD:223796	55/176 (31%)
		RRM5_RBM19_like	679..760	CDD:240764	28/80 (35%)
		RRM6_RBM19	785..864	CDD:241015	15/51 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45463967
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930