Protein Alignment Hrb98DE and HNRNPA3

DIOPT Version :9

• Sequence 1: NP_524543.1
• Gene: Hrb98DE / 43385
• FlyBaseID: FBgn0001215
• Length: 365
• Species: Drosophila melanogaster
• Sequence 2: NP_001317178.1
• Gene: HNRNPA3 / 220988
• HGNCID: 24941
• Length: 378
• Species: Homo sapiens
• Alignment Length: 379
• Identity: 188/379 - (49%)
• Similarity: 235/379 - (62%)
• Gaps: 49/379 - (12%)

  Fly     3 NSNQNQNGNSNGHDDDFPQDSITEPEHMRKLFIGGLDYRTTDENLKAHFEKWGNIVDVVVMKDPR 67
            :..:.:.....|||   |:    |||.:||||||||.:.|||::|:.||||||.:.|.|||:||:
Human    14 SGRRRRRRGEEGHD---PK----EPEQLRKLFIGGLSFETTDDSLREHFEKWGTLTDCVVMRDPQ 71

  Fly    68 TKRSRGFGFITYSHSSMIDEAQKSRPHKIDGRVVEPKRAVPRQDIDSPNAGATVKKLFVGALKDD 132
            |||||||||:|||....:|.|..:||||:|||||||||||.|:|...|.|..||||:|||.:|:|
Human    72 TKRSRGFGFVTYSCVEEVDAAMCARPHKVDGRVVEPKRAVSREDSVKPGAHLTVKKIFVGGIKED 136

  Fly   133 HDEQSIRDYFQHFGNIVDINIVIDKETGKKRGFAFVEFDDYDPVDKVVLQKQHQLNGKMVDVKKA 197
            .:|.::||||:.:|.|..|.::.|:::|||||||||.|||:|.|||:|:||.|.:||...:||||
Human   137 TEEYNLRDYFEKYGKIETIEVMEDRQSGKKRGFAFVTFDDHDTVDKIVVQKYHTINGHNCEVKKA 201

  Fly   198 LPKQ-----NDQQGGGGGRG---GPGGRAGGNRGNMG-GGNYGNQNGGGNWNNGGNNWGNNRGGN 253
            |.||     ..|:|.|||.|   |.||..||..||.| |||:|   |.|.:..||.....:.||.
Human   202 LSKQEMQSAGSQRGRGGGSGNFMGRGGNFGGGGGNFGRGGNFG---GRGGYGGGGGGSRGSYGGG 263

  Fly   254 DNWGNNSFGGGG---GGG------GGYGGGNNSWGN-------NNPWDNGNGGGNFGGGGNNWNN 302
            |. |.|.|||.|   |||      ||||||...:||       ...:|..|.|||||||  |:..
Human   264 DG-GYNGFGGDGGNYGGGPGYSSRGGYGGGGPGYGNQGGGYGGGGGYDGYNEGGNFGGG--NYGG 325

  Fly   303 GG--NDFGGY----QQNYGGGPQRGGGNFNNNRMQPYQGGGGFKAGGGNQGNYG 350
            ||  ||||.|    |.||  ||.:||.....:...||  |||:.:|||: |.||
Human   326 GGNYNDFGNYSGQQQSNY--GPMKGGSFGGRSSGSPY--GGGYGSGGGS-GGYG 374

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hrb98DE	NP_524543.1	RRM1_hnRNPA_like	32..109	CDD:241022	52/76 (68%)
		RRM_SF	123..195	CDD:302621	37/71 (52%)
HNRNPA3	NP_001317178.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..35		7/27 (26%)
		RRM1_hnRNPA_like	36..113	CDD:409992	52/76 (68%)
		RRM2_hnRNPA3	126..205	CDD:409996	43/78 (55%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	204..225		8/20 (40%)
		HnRNPA1	331..>347	CDD:402981	9/17 (53%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	336..378		18/44 (41%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	102	1.000	Domainoid score	I6828
eggNOG	1	0.900	-	-		E33208_3BA81
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	360	1.000	Inparanoid score	I2209
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG46466
OrthoDB	1	1.010	-	-		D1202220at2759
OrthoFinder	1	1.000	-	-		FOG0000779
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X431
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	9	8.880