DRSC/TRiP Functional Genomics Resources

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Protein Alignment Hrb98DE and LOC1270935

DIOPT Version :10

Sequence 1:NP_524543.1 Gene:Hrb98DE / 43385 FlyBaseID:FBgn0001215 Length:365 Species:Drosophila melanogaster
Sequence 2:XP_309663.5 Gene:LOC1270935 / 1270935 VectorBaseID:AGAMI1_003918 Length:569 Species:Anopheles gambiae


Alignment Length:350 Identity:116/350 - (33%)
Similarity:169/350 - (48%) Gaps:59/350 - (16%)


- Green bases have known domain annotations that are detailed below.


  Fly    33 LFIGGLDYRTTDENLKAHFEKWGNIVDVVVMKDPRTKRSRGFGFITYSHSSMIDEAQK---SRPH 94
            |.:.||.::||:|:|:.:||.:|.::.|.:.||.:|.:|:|:|||.::..    |:|.   |:.|
Mosquito   117 LIVLGLPWKTTEESLREYFETFGELLVVQIKKDSKTGQSKGYGFIRFARF----ESQMKALSKRH 177

  Fly    95 KIDGRVVEPKRAVPRQDIDSPNAGATVKKLFVGALKDDHDEQSIRDYFQHFGNIVDINIVIDKET 159
            .||.|..:.|  ||.....:.:  ....|:|:|.|.:|.:...|||||..:|.:.|  :.|.|..
Mosquito   178 LIDSRWCDVK--VPSSKDQTQH--QMPSKIFLGRLTEDINSDDIRDYFSKYGEVTD--VFIPKPF 236

  Fly   160 GKKRGFAFVEFDDYDP-VDKVVLQKQHQLNGKMVDVKKALPKQNDQQGGGGGRGGPGGRAGGNRG 223
               |.||||.|  .|| |.:.:..:.|.:.|..|.|..|.|:...            ||..| :|
Mosquito   237 ---RAFAFVTF--IDPHVAQSLCGEDHLIKGTSVYVSTASPRPEH------------GRHHG-KG 283

  Fly   224 NMGG--GNYGNQNGGGNWNNGGNNWGNNRGGNDNWGNNSFGGGGGGGGGYGGGNNSWG-----NN 281
            .|||  .||..:..||    ||:..|.:.|.||   .:..|||||||||.|||.::.|     .|
Mosquito   284 QMGGNFSNYDERGRGG----GGSGVGGSSGAND---YHRGGGGGGGGGGGGGGGHAVGPHVPAPN 341

  Fly   282 NPWDNGNGGGNFGGGGNNWNN--GGNDFGGYQQ---NYGGGPQRGGGNFNNNRMQP--------Y 333
            :.:.:|:|||:.|.|...:||  .||..|..||   ||.....:...|.:|....|        .
Mosquito   342 SSYHHGSGGGSEGAGPGGYNNMQSGNGGGCSQQPIWNYNEYTAQNRQNNSNIESMPNLQALGINS 406

  Fly   334 QGGGGFKAGGGNQGNYGGNNQGFNN 358
            .|..|.:.||...|.:||::.|..|
Mosquito   407 SGPNGQRGGGVGGGLHGGHHAGMGN 431

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Hrb98DENP_524543.1 RRM1_hnRNPA_like 32..109 CDD:409992 28/78 (36%)
RRM_SF 123..195 CDD:473069 26/72 (36%)
LOC1270935XP_309663.5 TDP43_N 11..85 CDD:465833
RRM1_TDP43 116..189 CDD:409760 27/77 (35%)
RRM2_TDP43 201..270 CDD:409761 27/75 (36%)
Blue background indicates that the domain is not in the aligned region.

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