DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment fkh and FOXD4L5

DIOPT Version :9

Sequence 1:	NP_001263038.1	Gene:	fkh / 43383	FlyBaseID:	FBgn0000659	Length:	692	Species:	Drosophila melanogaster
Sequence 2:	NP_001119806.1	Gene:	FOXD4L5 / 653427	HGNCID:	18522	Length:	416	Species:	Homo sapiens

Alignment Length:	128	Identity:	72/128 - (56%)
Similarity:	88/128 - (68%)	Gaps:	4/128 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly   209 AKPPYSYISLITMAIQNNPTRMLTLSEIYQFIMDLFPFYRQNQQRWQNSIRHSLSFNDCFVKIPR 273
            ||||||||:||||||..||.:.||||.|..||...||:||:....|||||||:||.|||||||||
Human   107 AKPPYSYIALITMAILQNPHKRLTLSGICAFISGRFPYYRRKFPAWQNSIRHNLSLNDCFVKIPR 171

  Fly   274 TPDKPGKGSFWTLHPDSGNMFENGCYLRRQKRFKDEKKEAIRQL-HKSP---SHSSLEATSPG 332
            .|..||||::|:|.|.|.:||:||.:|||:||||..:......| |..|   :|::|....||
Human   172 EPGHPGKGNYWSLDPASQDMFDNGSFLRRRKRFKRHQLTPGAHLPHPFPLPAAHAALHNPHPG 234

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fkh	NP_001263038.1	Forkhead_N	<120..209	CDD:254796	72/128 (56%)
fkh	NP_001263038.1	FH	210..298	CDD:214627	56/87 (64%)
FOXD4L5	NP_001119806.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..55
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	70..105
		Forkhead	108..194	CDD:278670	55/85 (65%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000010
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.910