DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment fkh and foxg1c

DIOPT Version :9

Sequence 1:	NP_001263038.1	Gene:	fkh / 43383	FlyBaseID:	FBgn0000659	Length:	692	Species:	Drosophila melanogaster
Sequence 2:	NP_001038680.1	Gene:	foxg1c / 571323	ZFINID:	ZDB-GENE-050419-26	Length:	379	Species:	Danio rerio

Alignment Length:	345	Identity:	105/345 - (30%)
Similarity:	141/345 - (40%)	Gaps:	114/345 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly   210 KPPYSYISLITMAIQNNPTRMLTLSEIYQFIMDLFPFYRQNQQRWQNSIRHSLSFNDCFVKIPRT 274
            |||:||.:||.|||:.:|.|.|||:.||:|||..||:||:|:|.|||||||:||.|.||||:||.
Zfish    90 KPPFSYNALIMMAIRQSPERRLTLNGIYEFIMGNFPYYRENRQGWQNSIRHNLSLNKCFVKVPRH 154

  Fly   275 PDKPGKGSFWTLHPDSGNMFENGC--YLRRQKRFKDEKKEAIRQLHKSPSHSSLEATSPGKKDHE 337
            .|.||||::|.|.|.|.::|..|.  .|||:.......|.|:    |..:..|..|.|.|.. ..
Zfish   155 YDDPGKGNYWMLDPSSDDVFIGGTTGKLRRRSTAASRAKLAM----KRGARLSSTAASAGLA-FA 214

  Fly   338 DSHH--------MHHHHHSRLDHHQHHKEAGGASIAGVNVLSAAHSKDAEALAMLHAN-AELCLS 393
            .|.:        :.|.|.|.                     :|||          |:| |...||
Zfish   215 GSFYWPVPPFVTLQHRHSSP---------------------AAAH----------HSNYAASVLS 248

  Fly   394 QQPQHVPTHHHHQHHQLQQEELSAMMANRCHPSLITDYHSSMHPLKQEPSGY-------TPSSHP 451
            |..:|..:              .|..|.|.           :.|..||.:.|       |.||..
Zfish   249 QSARHFSS--------------VAPAAERL-----------LIPSSQEATYYGMGCEQMTSSSSS 288

  Fly   452 FSINRLLPTESKADIKMYDMSQYAGYNALSPLTNSHAALGQDSYYQSLGYHAPAGTTSLXHHQYP 516
            ||.:..:|         ..:|....:|.||         .|.||:.|              ||.|
Zfish   289 FSTSASVP---------LPLSAPCSFNLLS---------NQSSYFYS--------------HQVP 321

  Fly   517 LAXGRAEQMLRSQQQQHLQQ 536
            ...|.:..   ||::.:|.:
Zfish   322 HTAGLSAW---SQEESYLSK 338

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fkh	NP_001263038.1	Forkhead_N	<120..209	CDD:254796
fkh	NP_001263038.1	FH	210..298	CDD:214627	52/87 (60%)
foxg1c	NP_001038680.1	FH	90..178	CDD:214627	52/87 (60%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000010
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910