DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment fkh and foxd1

DIOPT Version :9

Sequence 1:	NP_001263038.1	Gene:	fkh / 43383	FlyBaseID:	FBgn0000659	Length:	692	Species:	Drosophila melanogaster
Sequence 2:	NP_001008148.1	Gene:	foxd1 / 493510	XenbaseID:	XB-GENE-488077	Length:	329	Species:	Xenopus tropicalis

Alignment Length:	196	Identity:	81/196 - (41%)
Similarity:	114/196 - (58%)	Gaps:	23/196 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   173 YGAMPPGS------REMETGSPNSLGRSRVDKPTTYRRSYTHAKPPYSYISLITMAIQNNPTRML 231
            :|.:.|.|      ::...|:....|||.:            .|||||||:||||||..:|.:.|
Frog    37 HGDLLPTSPQSSATKDPYKGTGGGGGRSAL------------VKPPYSYIALITMAILQSPKKRL 89

  Fly   232 TLSEIYQFIMDLFPFYRQNQQRWQNSIRHSLSFNDCFVKIPRTPDKPGKGSFWTLHPDSGNMFEN 296
            |||||.:||.:.||:||:....|||||||:||.|||||||||.|..||||::|||.|:|.:||:|
Frog    90 TLSEICEFISNRFPYYREKFPAWQNSIRHNLSLNDCFVKIPREPGNPGKGNYWTLDPESADMFDN 154

  Fly   297 GCYLRRQKRFKDEKKEAIRQLHKSPSH---SSLEATSPGKKDHEDSHHMHHHHHSRLDHHQHHKE 358
            |.:|||:||||  :::|...:.:.|.|   :|..:..|....:.......|.|.:.:...|..::
Frog   155 GSFLRRRKRFK--RQQAPELVLREPGHFLPASAYSYGPYSCAYGIQLQPFHPHSALIAFQQQQQQ 217

  Fly   359 A 359
            |
Frog   218 A 218

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fkh	NP_001263038.1	Forkhead_N	<120..209	CDD:254796	7/41 (17%)
fkh	NP_001263038.1	FH	210..298	CDD:214627	57/87 (66%)
foxd1	NP_001008148.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..63		4/25 (16%)
foxd1	NP_001008148.1	Forkhead	68..153	CDD:365978	55/84 (65%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000010
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910