Protein Alignment fkh and foxo

DIOPT Version :10

• Sequence 1: NP_001263038.1
• Gene: fkh / 43383
• FlyBaseID: FBgn0000659
• Length: 692
• Species: Drosophila melanogaster
• Sequence 2: NP_650330.3
• Gene: foxo / 41709
• FlyBaseID: FBgn0038197
• Length: 622
• Species: Drosophila melanogaster
• Alignment Length: 651
• Identity: 155/651 - (23%)
• Similarity: 244/651 - (37%)
• Gaps: 147/651 - (22%)

  Fly   127 AMNSMGGNCMTPSSMSYASMGSPLGNMGGCMAMSAASMSAAGLSGTYGA---MPPGSREMETGSP 188
            ||:.:||:  .|..:.:........|...|............|..|..:   :.||.      |.
  Fly    20 AMDQLGGD--LPLDVGFEPQTRARSNTWPCPRPENFVEPTDELDSTKASNQQLAPGD------SQ 76

  Fly   189 NSLGRSRVDKPTTYRRSYTHAKPPYSYISLITMAIQNNPTRMLTLSEIYQFIMDLFPFYR----- 248
            .::..:...|..:.||   :|....||..|||.||.:...:.||||:||::::...|:::
  Fly    77 QAIQNANAAKKNSSRR---NAWGNLSYADLITHAIGSATDKRLTLSQIYEWMVQNVPYFKDKGDS 138

  Fly   249 QNQQRWQNSIRHSLSFNDCFVKIPRTPDKPGKGSFWTLHPDS---------GNMFENGCYLRRQK 304
            .:...|:|||||:||.::.|:::..  :..||.|:|.|:|::         ....|...|.:|:.
  Fly   139 NSSAGWKNSIRHNLSLHNRFMRVQN--EGTGKSSWWMLNPEAKPGKSVRRRAASMETSRYEKRRG 201

  Fly   305 RFKDEKKEAIRQL------HKSPSHSSLEATSPGKKDHEDSHHMHHHHHSRLDHHQHHKEAGGAS 363
            |.| ::.||:||.      ..:||.||  :.|.| .||.....:|.....:|......:.:..||
  Fly   202 RAK-KRVEALRQAGVVGLNDATPSPSS--SVSEG-LDHFPESPLHSGGGFQLSPDFRQRASSNAS 262

  Fly   364 IAGVNVLSAAHSKDAE---ALAMLHANAELCLSQQPQHVPTHHHHQHHQLQQEELSAMMANR--- 422
            ..|  .||...::|.|   ...:.:.|..:.              |.|....|||:..||:.
  Fly   263 SCG--RLSPIRAQDLEPDWGFPVDYQNTTMT--------------QAHAQALEELTGTMADELTL 311

  Fly   423 CHPSLITDYHSSMHPLKQEPSGYTPSSHPFSINRLLPTESKADIKMYDMSQYA------GYNALS 481
            |:........:|..|.:..|..|.|..|           .:|..:....|.||      |||.|.
  Fly   312 CNQQQQGFSAASGLPSQPPPPPYQPPQH-----------QQAQQQQQQQSPYALNGPASGYNTLQ 365

  Fly   482 PLTNS--HAALGQDSYYQSLGYHAPAGTTSLXHHQYP---------------LAXGRAEQMLRSQ 529
            |.:..  |.:|.....:.:....:|...|:. ...||               :. |.|:......
  Fly   366 PQSQCLLHRSLNCSCMHNARDGLSPNSVTTTMSPAYPNSEPSSDSLNTYSNVVLDGPADTAALMV 430

  Fly   530 QQQHLQQQHQQHQQQQQQHQ------------LHQQQQ-----------------QMQQSAQQLT 565
            |||..|||.||.....:.:.            |:.:.|                 .:::..||..
  Fly   431 QQQQQQQQQQQLSASLEDNNCASTLIGQCLEVLNNEAQPIDEFNLENFPVGNLECNVEELLQQEM 495

  Fly   566 SAS-----NTPATSAK---ASGKAGSASASGSG--SGSGSGSGSNYS--------QKLQQQHQQQ 612
            |..     |.|..:..   .:..:|..|.|...  |...|.|||:.|        |:.|||.|.|
  Fly   496 SYGGLLDINIPLATVNTNLVNSSSGPLSISNISNLSNISSNSGSSLSLNQLQAQLQQQQQQQQAQ 560

  Fly   613 QQQQAAAQQQHHQQQQQLLQELQEDSSNITSDLSEEQLQQHQAAQQQLYNNYQQYAAAAGYRNWN 677
            |||||..|||.|||.||.|.....::|:.:.:|:.:....:..|:.|    |.|.:......:|.
  Fly   561 QQQQAQQQQQQHQQHQQQLLLNNNNNSSSSLELATQTATTNLNARVQ----YSQPSVVTSPPSWV 621

  Fly   678 H 678
            |
  Fly   622 H 622

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
fkh	NP_001263038.1	Forkhead_N	<120..209	CDD:369872	15/84 (18%)
		FH_dFKH	210..307	CDD:410815	33/110 (30%)
foxo	NP_650330.3	FH_FOXO	96..175	CDD:410806	27/80 (34%)