DRSC/TRiP Functional Genomics Resources

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Protein Alignment fkh and foxc2

DIOPT Version :9

Sequence 1:NP_001263038.1 Gene:fkh / 43383 FlyBaseID:FBgn0000659 Length:692 Species:Drosophila melanogaster
Sequence 2:NP_998857.1 Gene:foxc2 / 407875 XenbaseID:XB-GENE-481382 Length:463 Species:Xenopus tropicalis


Alignment Length:469 Identity:140/469 - (29%)
Similarity:196/469 - (41%) Gaps:127/469 - (27%)


- Green bases have known domain annotations that are detailed below.


  Fly   160 SAASMSAAGL------------SGTYGAMP------PGSREMETGSPNSLGRSRVDKPTTYRRSY 206
            |.|..:|.|:            :||||:|.      |...:...|...|.|.....:|...:   
 Frog     6 SVADPNALGVVPYLSEQNYYRAAGTYGSMATPMSVYPAHEQYTPGMARSYGPYHHHQPAAPK--- 67

  Fly   207 THAKPPYSYISLITMAIQNNPTRMLTLSEIYQFIMDLFPFYRQNQQRWQNSIRHSLSFNDCFVKI 271
            ...|||||||:||||||||.|.:.:||:.|||||||.|||||:|:|.|||||||:||.|:||||:
 Frog    68 DLVKPPYSYIALITMAIQNAPDKKITLNGIYQFIMDRFPFYRENKQGWQNSIRHNLSLNECFVKV 132

  Fly   272 PRTPDKPGKGSFWTLHPDSGNMFENGCYLRRQKRFKDEKKEAIRQLH-----------------K 319
            ||...||||||:|||.|||.||||||.:|||::|||  ||:..|:..                 :
 Frog   133 PRDDKKPGKGSYWTLDPDSYNMFENGSFLRRRRRFK--KKDVSREKEDRILKDQGKVQGPIPSLE 195

  Fly   320 SPSH----------------SSLEATSP-GKKDHEDSHHMHHHHHSRLDHH---QHHKEAGGASI 364
            .|.|                :.:|..|| |....:||........|....:   ..|..:.|.|:
 Frog   196 LPKHDKKIVIKSESPELPVITKVENLSPDGGSAMQDSPRSVASTPSVSTENSIPDQHPASNGFSV 260

  Fly   365 AGVNVLSAAHSKDAEALAMLHANAELCLSQQPQHVPTHHHHQH-----------------HQLQQ 412
            ..:..|..:...|...:.     |..|.:.....:|.::....                 :|...
 Frog   261 ENIMTLRTSPHGDLSPVP-----AVPCRTGMVPSLPINYTQTQSSVYSQACTQSMDTSGSYQCSM 320

  Fly   413 EELSAMMANR----CHPSLI----TDYHS-SMHPLKQEPSG-----YTPSSHPFSINRLLPTESK 463
            ..:|....:|    |.||.:    :|:|: :..||.....|     ...|||    ::...|..:
 Frog   321 RAMSLYTGDRPSHMCAPSTLEEATSDHHNGTASPLNSMSLGSGQESVLTSSH----HQQTATGGQ 381

  Fly   464 ADIKMY-----DMSQYAGYN---------ALSPLTNSHAALGQDSYYQSLGYHAPAGTT------ 508
            .....|     |:|..:|:|         .:..:.||| .||.:|  .:|..|..:|.|      
 Frog   382 TAAPWYLNPGADISHLSGHNFGSQQQTFPNVREMFNSH-RLGIES--SALSEHQVSGNTSCQIPY 443

  Fly   509 ----SLXHHQYPLA 518
                |: .|..|.|
 Frog   444 RSAPSIYRHSSPYA 457

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
fkhNP_001263038.1 Forkhead_N <120..209 CDD:254796 14/66 (21%)
FH 210..298 CDD:214627 65/87 (75%)
foxc2NP_998857.1 Forkhead 71..156 CDD:306709 62/84 (74%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0000010
OrthoInspector 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.910

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