Protein Alignment fkh and foxc2

DIOPT Version :10

• Sequence 1: NP_001263038.1
• Gene: fkh / 43383
• FlyBaseID: FBgn0000659
• Length: 692
• Species: Drosophila melanogaster
• Sequence 2: NP_998857.1
• Gene: foxc2 / 407875
• XenbaseID: XB-GENE-481382
• Length: 463
• Species: Xenopus tropicalis
• Alignment Length: 469
• Identity: 140/469 - (29%)
• Similarity: 196/469 - (41%)
• Gaps: 127/469 - (27%)

  Fly   160 SAASMSAAGL------------SGTYGAMP------PGSREMETGSPNSLGRSRVDKPTTYRRSY 206
            |.|..:|.|:            :||||:|.      |...:...|...|.|.....:|...:
 Frog     6 SVADPNALGVVPYLSEQNYYRAAGTYGSMATPMSVYPAHEQYTPGMARSYGPYHHHQPAAPK--- 67

  Fly   207 THAKPPYSYISLITMAIQNNPTRMLTLSEIYQFIMDLFPFYRQNQQRWQNSIRHSLSFNDCFVKI 271
            ...|||||||:||||||||.|.:.:||:.|||||||.|||||:|:|.|||||||:||.|:||||:
 Frog    68 DLVKPPYSYIALITMAIQNAPDKKITLNGIYQFIMDRFPFYRENKQGWQNSIRHNLSLNECFVKV 132

  Fly   272 PRTPDKPGKGSFWTLHPDSGNMFENGCYLRRQKRFKDEKKEAIRQLH-----------------K 319
            ||...||||||:|||.|||.||||||.:|||::|||  ||:..|:..                 :
 Frog   133 PRDDKKPGKGSYWTLDPDSYNMFENGSFLRRRRRFK--KKDVSREKEDRILKDQGKVQGPIPSLE 195

  Fly   320 SPSH----------------SSLEATSP-GKKDHEDSHHMHHHHHSRLDHH---QHHKEAGGASI 364
            .|.|                :.:|..|| |....:||........|....:   ..|..:.|.|:
 Frog   196 LPKHDKKIVIKSESPELPVITKVENLSPDGGSAMQDSPRSVASTPSVSTENSIPDQHPASNGFSV 260

  Fly   365 AGVNVLSAAHSKDAEALAMLHANAELCLSQQPQHVPTHHHHQH-----------------HQLQQ 412
            ..:..|..:...|...:.     |..|.:.....:|.::....                 :|...
 Frog   261 ENIMTLRTSPHGDLSPVP-----AVPCRTGMVPSLPINYTQTQSSVYSQACTQSMDTSGSYQCSM 320

  Fly   413 EELSAMMANR----CHPSLI----TDYHS-SMHPLKQEPSG-----YTPSSHPFSINRLLPTESK 463
            ..:|....:|    |.||.:    :|:|: :..||.....|     ...|||    ::...|..:
 Frog   321 RAMSLYTGDRPSHMCAPSTLEEATSDHHNGTASPLNSMSLGSGQESVLTSSH----HQQTATGGQ 381

  Fly   464 ADIKMY-----DMSQYAGYN---------ALSPLTNSHAALGQDSYYQSLGYHAPAGTT------ 508
            .....|     |:|..:|:|         .:..:.||| .||.:|  .:|..|..:|.|
 Frog   382 TAAPWYLNPGADISHLSGHNFGSQQQTFPNVREMFNSH-RLGIES--SALSEHQVSGNTSCQIPY 443

  Fly   509 ----SLXHHQYPLA 518
                |: .|..|.|
 Frog   444 RSAPSIYRHSSPYA 457

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
fkh	NP_001263038.1	Forkhead_N	<120..209	CDD:369872	14/66 (21%)
		FH_dFKH	210..307	CDD:410815	70/96 (73%)
foxc2	NP_998857.1	FH_FOXC1	66..158	CDD:410818	64/94 (68%)