Protein Alignment fkh and FOXI2

DIOPT Version :9

• Sequence 1: NP_001263038.1
• Gene: fkh / 43383
• FlyBaseID: FBgn0000659
• Length: 692
• Species: Drosophila melanogaster
• Sequence 2: NP_997309.2
• Gene: FOXI2 / 399823
• HGNCID: 32448
• Length: 318
• Species: Homo sapiens
• Alignment Length: 343
• Identity: 99/343 - (28%)
• Similarity: 135/343 - (39%)
• Gaps: 131/343 - (38%)

  Fly    10 PSSAPVSMASSGGGGPPSGGGGGGGGGGGGGPPPPSNNNPNPTSNGGSMSPLARSAYTMNSMGLP 74
            |||||...|.: ...||....|..|..|||         |....|..::||.:.::
Human    10 PSSAPPGQAQA-TAHPPGYEPGDLGAVGGG---------PLLWVNAPALSPKSYAS--------- 55

  Fly    75 VGGMSSVSPQAAATFSSSVLDSAAAVASMSASMSASMSASMNASMNGSMGAAAMNSMGGNCMTPS 139
              |.....|.||.
Human    56 --GPGPAPPYAAP---------------------------------------------------- 66

  Fly   140 SMSYASMGSPLGNMGGCMAMSAASMSAAGLSGTYGAMPPGSREMETGSPNSLGRSRVDKPTTYRR 204
              ||.:.|..||..||   ::.|.::...||        |.:|:
Human    67 --SYGAPGPLLGAPGG---LAGADLAWLSLS--------GQQEL--------------------- 97

  Fly   205 SYTHAKPPYSYISLITMAIQNNPTRMLTLSEIYQFIMDLFPFYRQNQQRWQNSIRHSLSFNDCFV 269
             ....:|||||.:||.||||:.|.|.||||:|||::...||||::::..|||||||:||.||||.
Human    98 -LRLVRPPYSYSALIAMAIQSAPLRKLTLSQIYQYVAGNFPFYKRSKAGWQNSIRHNLSLNDCFK 161

  Fly   270 KIPRTPDKPGKGSFWTLHPDSGNMFENGCYLRRQKRFKDEKKEAIR------------------- 315
            |:||..|.||||::|||.|:...||:||.:.|::|| :.|...|:|
Human   162 KVPRDEDDPGKGNYWTLDPNCEKMFDNGNFRRKRKR-RAEASAAVRSGARSVGGAEAPALEPPSA 225

  Fly   316 ---QLHKSPSHSSLEATS 330
               .|..|||.|:.||.:
Human   226 ACLDLQASPSPSAPEAAT 243

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
fkh	NP_001263038.1	Forkhead_N	<120..209	CDD:254796	12/88 (14%)
		FH	210..298	CDD:214627	52/87 (60%)
FOXI2	NP_997309.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..30		8/20 (40%)
		Forkhead	102..188	CDD:278670	51/85 (60%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000010
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.910