DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment fkh and foxi4.2

DIOPT Version :9

Sequence 1:	NP_001263038.1	Gene:	fkh / 43383	FlyBaseID:	FBgn0000659	Length:	692	Species:	Drosophila melanogaster
Sequence 2:	NP_989265.1	Gene:	foxi4.2 / 394878	XenbaseID:	XB-GENE-487658	Length:	363	Species:	Xenopus tropicalis

Alignment Length:	207	Identity:	77/207 - (37%)
Similarity:	112/207 - (54%)	Gaps:	23/207 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   143 YASMGSPLGNMGGCMAMSAASMSAAGLSGTYGAMPPG----SREMETGSPNSLGRSRVD--KPTT 201
            |.|..:|...:||....:|.:.|.:  ...|  |||.    .|:....|| :.|.:.:.  ...:
Frog    57 YTSPANPYLWLGGHGVNNAPNYSPS--PAPY--MPPSFGAPQRQFLPNSP-AFGGTELSWMSAAS 116

  Fly   202 YRRSYTHAKPPYSYISLITMAIQNNPTRMLTLSEIYQFIMDLFPFYRQNQQRWQNSIRHSLSFND 266
            ........:|||||.:||.||||:...|.||||:|||::.:.||||::::..|||||||:||.||
Frog   117 QEELLKMVRPPYSYSALIAMAIQHASDRRLTLSQIYQYVAENFPFYKKSKAGWQNSIRHNLSLND 181

  Fly   267 CFVKIPRTPDKPGKGSFWTLHPDSGNMFENGCYLRRQKRFKDEKKEAIRQL---HKSP------- 321
            ||.|:||..:.||||::|||.|:...||:||.:.|::|...|.....|.::   |.:|
Frog   182 CFKKVPRDENDPGKGNYWTLDPNCEKMFDNGNFRRKRKPKSDANSAKIAKIGEDHLNPKGKESPP 246

  Fly   322 --SHSSLEATSP 331
              :.||.|..||
Frog   247 MITPSSPEEPSP 258

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fkh	NP_001263038.1	Forkhead_N	<120..209	CDD:254796	15/71 (21%)
fkh	NP_001263038.1	FH	210..298	CDD:214627	50/87 (57%)
foxi4.2	NP_989265.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..24
		Forkhead	125..210	CDD:306709	48/84 (57%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	210..269		13/49 (27%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	344..363
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000010
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910