Protein Alignment fkh and FOXI3

DIOPT Version :9

• Sequence 1: NP_001263038.1
• Gene: fkh / 43383
• FlyBaseID: FBgn0000659
• Length: 692
• Species: Drosophila melanogaster
• Sequence 2: NP_001129121.1
• Gene: FOXI3 / 344167
• HGNCID: 35123
• Length: 420
• Species: Homo sapiens
• Alignment Length: 500
• Identity: 133/500 - (26%)
• Similarity: 183/500 - (36%)
• Gaps: 168/500 - (33%)

  Fly     5 YAEPPPSSAP--VSMASSGGGGPPSGGGGGGGGGGGGGPPPPSNNNPNPTSNGGSMSPLARSAYT 67
            ||.||.::|.  :.:...|.|||||..........|..||||    |...:.|..:.|
Human    42 YAAPPAAAANPYLWLNGPGVGGPPSAAAAAAAAYLGAPPPPP----PPGAAAGPFLQP------- 95

  Fly    68 MNSMGLPVGGMSSVSPQAAATFSSSVLDSAAAVASMSASMSASMSASMNASMNGSMGAAAMNSMG 132
                           |.||.||..|....|
Human    96 ---------------PPAAGTFGCSQRPFA----------------------------------- 110

  Fly   133 GNCMTPSSMSYASMGSPLGNMGGCMAMSAASMSAAGLSGTYGAMPPGSRE--METGSPNSLGRSR 195
                .|:..:.||..:|.|                  .|..|.:...|||  |:.
Human   111 ----QPAPAAPASPAAPAG------------------PGELGWLSMASREDLMKM---------- 143

  Fly   196 VDKPTTYRRSYTHAKPPYSYISLITMAIQNNPTRMLTLSEIYQFIMDLFPFYRQNQQRWQNSIRH 260
                         .:|||||.:||.||||:.|.|.||||.||||:.|.||||::::..|||||||
Human   144 -------------VRPPYSYSALIAMAIQSAPERKLTLSHIYQFVADSFPFYQRSKAGWQNSIRH 195

  Fly   261 SLSFNDCFVKIPRTPDKPGKGSFWTLHPDSGNMFENGCYLRRQKRFKDEKKEAIRQLHKSPSHSS 325
            :||.||||.|:||..|.||||::|||.|:...||:||.:.|::||..:....:......|.|...
Human   196 NLSLNDCFKKVPRDEDDPGKGNYWTLDPNCEKMFDNGNFRRKRKRRSEASNGSTVAAGTSKSEEG 260

  Fly   326 LEA---TSPGKKDHEDSHHMHHHHHSRLDHHQHHKE-----------AGGASIAGVNVLSAAHSK 376
            |.:   :..|.|..|:|       .|.|....|..|           .||..:.....|:...|
Human   261 LSSGLGSGVGGKPEEES-------PSTLLRPSHSPEPPEGTKSTASSPGGPMLTSTPCLNTFFS- 317

  Fly   377 DAEALAMLHANAELCLSQQPQHVPTHHHHQHHQLQQEELSAMMANRCHPSLITD--------YHS 433
               :|:.|..::    |...|.......|...|..|...|.:.:    |:.|::        .:|
Human   318 ---SLSSLSVSS----SVSTQRALPGSRHLGIQGAQLPSSGVFS----PTSISEASADTLQLSNS 371

  Fly   434 SMHPLKQEPSGYTP--------SSHPFS--------INRLL-PTE 461
            :.:...|..|.|:|        .|.|||        :|.|: |.|
Human   372 TSNSTGQRSSYYSPFPASTSGGQSSPFSSPFHNFSMVNSLIYPRE 416

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
fkh	NP_001263038.1	Forkhead_N	<120..209	CDD:254796	11/90 (12%)
		FH	210..298	CDD:214627	54/87 (62%)
FOXI3	NP_001129121.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	103..122		5/57 (9%)
		Forkhead	145..231	CDD:278670	53/85 (62%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	234..306		16/78 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	364..396		5/31 (16%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000010
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.910