Protein Alignment fkh and FOXA3

DIOPT Version :9

• Sequence 1: NP_001263038.1
• Gene: fkh / 43383
• FlyBaseID: FBgn0000659
• Length: 692
• Species: Drosophila melanogaster
• Sequence 2: NP_004488.2
• Gene: FOXA3 / 3171
• HGNCID: 5023
• Length: 350
• Species: Homo sapiens
• Alignment Length: 428
• Identity: 155/428 - (36%)
• Similarity: 198/428 - (46%)
• Gaps: 110/428 - (25%)

  Fly    80 SVSPQAAATFSSSVLDSAAAVASMSASMSASMSASMNASMNGSMGAAAMNSMGGNCMTPSSMSYA 144
            |..|:|...:|     ....|.:| |.:::.|:.:..:|.....|..|.....|....|:.
Human    16 SYYPEAGEVYS-----PVTPVPTM-APLNSYMTLNPLSSPYPPGGLPASPLPSGPLAPPAP---- 70

  Fly   145 SMGSPLGNMGGCMAMSAASMSAAGLSGTYGAMPPG---SREMETGSPNSLGRSRVDKPTTYRRSY 206
              .:|||.....:.:|..|.|:.     |||..||   .:||               |..|||..
Human    71 --AAPLGPTFPGLGVSGGSSSSG-----YGAPGPGLVHGKEM---------------PKGYRRPL 113

  Fly   207 THAKPPYSYISLITMAIQNNPTRMLTLSEIYQFIMDLFPFYRQNQQRWQNSIRHSLSFNDCFVKI 271
            .|||||||||||||||||..|.:|||||||||:||||||:||:|||||||||||||||||||||:
Human   114 AHAKPPYSYISLITMAIQQAPGKMLTLSEIYQWIMDLFPYYRENQQRWQNSIRHSLSFNDCFVKV 178

  Fly   272 PRTPDKPGKGSFWTLHPDSGNMFENGCYLRRQKRFKDEKKEAIRQLHKSPSHSSLEATSPGKKDH 336
            .|:||||||||:|.|||.||||||||||||||||||.|:|.
Human   179 ARSPDKPGKGSYWALHPSSGNMFENGCYLRRQKRFKLEEKV------------------------ 219

  Fly   337 EDSHHMHHHHHSRLDHHQHHKEAGGASIAGVNVLSAAHSKDAEALAMLHANAELCLSQQPQHVPT 401
                               .|...||:....|...:|.|....|..:...      .|.|...|
Human   220 -------------------KKGGSGAATTTRNGTGSAASTTTPAATVTSP------PQPPPPAP- 258

  Fly   402 HHHHQHHQLQQEELSAMMANRCHPSLITDYHSSMH---PLKQE-PSGYTPSSHPFSINRLLPTES 462
                :......|::.|:...  .|:..|.|.:.:.   .||.: |..:   :||||||.|:..::
Human   259 ----EPEAQGGEDVGALDCG--SPASSTPYFTGLELPGELKLDAPYNF---NHPFSINNLMSEQT 314

  Fly   463 KADIKMYDMSQYAGYNALSPLTNSHAALGQDS-YYQSL 499
            .|..|: |:. :.||.|..         |:.. |||.|
Human   315 PAPPKL-DVG-FGGYGAEG---------GEPGVYYQGL 341

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
fkh	NP_001263038.1	Forkhead_N	<120..209	CDD:254796	21/91 (23%)
		FH	210..298	CDD:214627	74/87 (85%)
FOXA3	NP_004488.2	FH	117..205	CDD:214627	74/87 (85%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	217..276		13/114 (11%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG3563
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1181467at2759
OrthoFinder	1	1.000	-	-		FOG0000010
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR11829
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	7	6.880