DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment fkh and Foxi2

DIOPT Version :9

Sequence 1:	NP_001263038.1	Gene:	fkh / 43383	FlyBaseID:	FBgn0000659	Length:	692	Species:	Drosophila melanogaster
Sequence 2:	NP_899016.2	Gene:	Foxi2 / 270004	MGIID:	3028075	Length:	311	Species:	Mus musculus

Alignment Length:	225	Identity:	83/225 - (36%)
Similarity:	124/225 - (55%)	Gaps:	24/225 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   133 GNCMTPSSMSYA-----SMGSPLGNMGGCMAMSAASMSAA------GLSGTYGAMP---PGSREM 183
            |:|..|..::.|     |.|....:.|..:.:::|::|.|      |.:.:|.|..   |||...
Mouse     9 GSCSVPHGLTRAIAHPPSYGRTDLSSGRRLWVNSAALSPAPYATGPGPAPSYAAATLAVPGSLLG 73

  Fly   184 ETGSPNSLGRSRVD----KPTTYRRSYTHAKPPYSYISLITMAIQNNPTRMLTLSEIYQFIMDLF 244
            .:|     |.:..|    ..:..:......:|||||.:||.||||:.|.|.||||:|||::...|
Mouse    74 ASG-----GLAGADLAWLSLSGQQELLRLVRPPYSYSALIAMAIQSAPLRRLTLSQIYQYVAGNF 133

  Fly   245 PFYRQNQQRWQNSIRHSLSFNDCFVKIPRTPDKPGKGSFWTLHPDSGNMFENGCYLRRQKRFKDE 309
            |||::::..|||||||:||.||||.|:||..:.||||::|||.|:...||:||.: ||::|.:.|
Mouse   134 PFYKRSKAGWQNSIRHNLSLNDCFKKVPRDENDPGKGNYWTLDPNCEKMFDNGNF-RRKRRRRGE 197

  Fly   310 KKEAIRQLHKSPSHSSLEATSPGKKDHEDS 339
            ..||......||..::||......:|.:.|
Mouse   198 TSEAAVPGASSPEGTALEPRGSTPQDPQTS 227

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fkh	NP_001263038.1	Forkhead_N	<120..209	CDD:254796	19/93 (20%)
fkh	NP_001263038.1	FH	210..298	CDD:214627	51/87 (59%)
Foxi2	NP_899016.2	Forkhead	99..184	CDD:333958	49/84 (58%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	188..237		12/41 (29%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	263..294
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000010
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.910