DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment fkh and Foxa2

DIOPT Version :9

Sequence 1:NP_001263038.1 Gene:fkh / 43383 FlyBaseID:FBgn0000659 Length:692 Species:Drosophila melanogaster
Sequence 2:XP_006235201.1 Gene:Foxa2 / 25099 RGDID:2808 Length:465 Species:Rattus norvegicus


Alignment Length:494 Identity:197/494 - (39%)
Similarity:253/494 - (51%) Gaps:109/494 - (22%)


- Green bases have known domain annotations that are detailed below.


  Fly    64 SAYTMNSMGLPVGGMSSVSPQAAATFSSSVLDSAAAVASMSASMSASMSASM---------NASM 119
            |...||: .|.:.||::....:||...|...:.:|...:||:.:.|.||.|:         .|.|
  Rat    33 SVSNMNA-SLGMNGMNTYMSMSAAAMGSGSGNMSAGSMNMSSYVGAGMSPSLAGMSPGAGAMAGM 96

  Fly   120 NGSMGAAAMNSMGGNCMTPSSMSYASMGSPLGNMGGCMAMSAASMSAAGLSGTYGAMPPGSREME 184
            :||.|||.:..||.: ::||.       ||||...               :|..|.:.|.: .|.
  Rat    97 SGSAGAAGVAGMGPH-LSPSL-------SPLGGQA---------------AGAMGGLAPYA-NMN 137

  Fly   185 TGSP--NSLGRSRVDKPTTYRRSYTHAKPPYSYISLITMAIQNNPTRMLTLSEIYQFIMDLFPFY 247
            :.||  ...|.||...|.||||||||||||||||||||||||.:|.:|||||||||:||||||||
  Rat   138 SMSPMYGQAGLSRARDPKTYRRSYTHAKPPYSYISLITMAIQQSPNKMLTLSEIYQWIMDLFPFY 202

  Fly   248 RQNQQRWQNSIRHSLSFNDCFVKIPRTPDKPGKGSFWTLHPDSGNMFENGCYLRRQKRFKDEKKE 312
            |||||||||||||||||||||:|:||:|||||||||||||||||||||||||||||||||.||:.
  Rat   203 RQNQQRWQNSIRHSLSFNDCFLKVPRSPDKPGKGSFWTLHPDSGNMFENGCYLRRQKRFKCEKQL 267

  Fly   313 AIRQLHKSPSHSSLEATSPGKKDHE-----------DSHHMHHHHHSRLDHHQHHKEAGGASIAG 366
            |:::...:.|... :.|:||.:..:           ::.......||.....|.||..|      
  Rat   268 ALKEAAGAGSGGG-KKTAPGTQASQVQLGEAAGSASETPAGTESPHSSASPCQEHKRGG------ 325

  Fly   367 VNVLSAAHSKDAEALAMLHANAELCLSQQPQHVPTHHHHQHHQLQQEELSAMMANRCHPSLITDY 431
               ||......|.||:            .|:..|:...      ||:..:.::....||.|..:.
  Rat   326 ---LSELKGTPASALS------------PPEPAPSPGQ------QQQAAAHLLVPPHHPGLPPEA 369

  Fly   432 HSSMHPLKQEPSGYTPSSHPFSINRLLPTES------------KADIKMYD--MSQYAGYN---- 478
            |     ||  |..:...:||||||.|:.:|.            |.|:|.|:  |....||.    
  Rat   370 H-----LK--PEHHYAFNHPFSINNLMSSEQQHHHSHHHHQPHKMDLKTYEQVMHYPGGYGSPMP 427

  Fly   479 ---ALSPLTN----SHAALGQD-SYYQSLGYHAPAGTTS 509
               |:.|:||    ..:.|..| ||||.: |..|...:|
  Rat   428 GSLAMGPVTNKAGLDASPLAADTSYYQGV-YSRPIMNSS 465

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
fkhNP_001263038.1 Forkhead_N <120..209 CDD:254796 30/90 (33%)
FH 210..298 CDD:214627 79/87 (91%)
Foxa2XP_006235201.1 Forkhead_N 23..164 CDD:254796 48/155 (31%)
FH 165..253 CDD:214627 79/87 (91%)
HNF_C 381..454 CDD:286443 23/72 (32%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C166353826
Domainoid 1 1.000 166 1.000 Domainoid score I3778
eggNOG 1 0.900 - - E2759_KOG3563
Hieranoid 1 1.000 - -
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 259 1.000 Inparanoid score I3050
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D1181467at2759
OrthoFinder 1 1.000 - - FOG0000010
OrthoInspector 1 1.000 - - otm45009
orthoMCL 1 0.900 - - OOG6_105963
Panther 1 1.100 - - O PTHR11829
Phylome 1 0.910 - -
SonicParanoid 1 1.000 - - X1772
SwiftOrtho 1 1.000 - -
TreeFam 1 0.960 - -
1413.760

Return to query results.
Submit another query.