DRSC/TRiP Functional Genomics Resources

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Protein Alignment fkh and FOXI1

DIOPT Version :9

Sequence 1:NP_001263038.1 Gene:fkh / 43383 FlyBaseID:FBgn0000659 Length:692 Species:Drosophila melanogaster
Sequence 2:NP_036320.2 Gene:FOXI1 / 2299 HGNCID:3815 Length:378 Species:Homo sapiens


Alignment Length:336 Identity:103/336 - (30%)
Similarity:141/336 - (41%) Gaps:107/336 - (31%)


- Green bases have known domain annotations that are detailed below.


  Fly   165 SAAGLSGT-YGAMP-PGSREMETGSPNSLGRSRVDKPTTYRRSYTHAKPPYSYISLITMAIQNNP 227
            |.:||.|: .|.:| |...|:                      ....:|||||.:||.|||...|
Human    98 SVSGLGGSDLGWLPIPSQEEL----------------------MKLVRPPYSYSALIAMAIHGAP 140

  Fly   228 TRMLTLSEIYQFIMDLFPFYRQNQQRWQNSIRHSLSFNDCFVKIPRTPDKPGKGSFWTLHPDSGN 292
            .:.||||:|||::.|.||||.:::..|||||||:||.||||.|:||..|.||||::|||.|:...
Human   141 DKRLTLSQIYQYVADNFPFYNKSKAGWQNSIRHNLSLNDCFKKVPRDEDDPGKGNYWTLDPNCEK 205

  Fly   293 MFENGCYLRRQKRFKDEKKEAIRQLHKSPSHSSLEATSPGKKDHEDSHHMHHHHHSRLDHHQHHK 357
            ||:||.:.|::|| |.:...:...|....:.|||...||...:.:|.          ||      
Human   206 MFDNGNFRRKRKR-KSDVSSSTASLALEKTESSLPVDSPKTTEPQDI----------LD------ 253

  Fly   358 EAGGASIAGVNVLSAAHSKDAEALAMLHANAELCLSQQPQHVPTHHHHQHHQLQQEELSAMMANR 422
               |||..|..                 ::.|...|..|...|                      
Human   254 ---GASPGGTT-----------------SSPEKRPSPPPSGAP---------------------- 276

  Fly   423 CHPSLITDYHSSMHPLKQEPSGYTPSSHPFSINRLLPTESKADIKMYDMSQYAG-----YNALSP 482
            |    :..:.|||   ....||.:|:|||.....|.|          :.|...|     :|:.||
Human   277 C----LNSFLSSM---TAYVSGGSPTSHPLVTPGLSP----------EPSDKTGQNSLTFNSFSP 324

  Fly   483 LTN--SHAALG 491
            |||  :|:..|
Human   325 LTNLSNHSGGG 335

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
fkhNP_001263038.1 Forkhead_N <120..209 CDD:254796 8/45 (18%)
FH 210..298 CDD:214627 51/87 (59%)
FOXI1NP_036320.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..26
FH 123..211 CDD:214627 51/87 (59%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 208..278 24/132 (18%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0000010
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.910

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