back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment fkh and FOXD4

DIOPT Version :9

Sequence 1:	NP_001263038.1	Gene:	fkh / 43383	FlyBaseID:	FBgn0000659	Length:	692	Species:	Drosophila melanogaster
Sequence 2:	NP_997188.2	Gene:	FOXD4 / 2298	HGNCID:	3805	Length:	439	Species:	Homo sapiens

Alignment Length:	332	Identity:	101/332 - (30%)
Similarity:	144/332 - (43%)	Gaps:	110/332 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly   209 AKPPYSYISLITMAIQNNPTRMLTLSEIYQFIMDLFPFYRQNQQRWQNSIRHSLSFNDCFVKIPR 273
            ||||.|||:||||||..:|.:.||||.|..||.|.||:||:....|||||||:||.|||||||||
Human   103 AKPPSSYIALITMAILQSPHKRLTLSGICAFISDRFPYYRRKFPAWQNSIRHNLSLNDCFVKIPR 167

  Fly   274 TPDKPGKGSFWTLHPDSGNMFENGCYLRRQKRFKDEKKEAIRQL-HKSP---SHSSLE------- 327
            .|.:||||::|:|.|.|.:||:||.:|||:|||:..:......| |..|   :|::|.
Human   168 EPGRPGKGNYWSLDPASQDMFDNGSFLRRRKRFQRHQPTPGAHLPHPFPLPAAHAALHNPRPGPL 232

  Fly   328 ---------------ATSPGKKDHEDSHHMHHHHHSR---------------------------- 349
                           .|.||::.:.    :.|.|..|
Human   233 LGAPAPPQPVPGAYPNTGPGRRPYA----LLHPHPPRYLLLSAPAYAGAPKKAEGADLATPAPFP 293

  Fly   350 -LDHH------------QHHKEAGGASIAGVNVLSAAHSKDAEAL-----------AMLHANAEL 390
             ...|            :.|:|| .||::.:.|......:..:.|           |...::.:.
Human   294 CCSPHLVLSLGRRARVWRRHREA-DASLSALRVSCKGSGERVQGLRRVCPRPRGATAPCSSDRQA 357

  Fly   391 C---LSQQPQHVPTHHHHQHHQLQQEELSAMMANRCHP---SLITDYHSSMHPLKQ-----EPSG 444
            |   |.||.:|            |:|:    .||.|.|   :::..:.|:...|.:     |.||
Human   358 CRTILQQQQRH------------QEED----CANGCAPTKGAVLGGHLSAASALLRYQAVAEGSG 406

  Fly   445 YTPSSHP 451
            .|..:.|
Human   407 LTSLAAP 413

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.