Sequence 1: | NP_001263038.1 | Gene: | fkh / 43383 | FlyBaseID: | FBgn0000659 | Length: | 692 | Species: | Drosophila melanogaster |
---|---|---|---|---|---|---|---|---|---|
Sequence 2: | NP_001444.2 | Gene: | FOXC1 / 2296 | HGNCID: | 3800 | Length: | 553 | Species: | Homo sapiens |
Alignment Length: | 592 | Identity: | 169/592 - (28%) |
---|---|---|---|
Similarity: | 235/592 - (39%) | Gaps: | 163/592 - (27%) |
- Green bases have known domain annotations that are detailed below.
Fly 145 SMGSP--LG---NMGGCMAMSAASMSAAGLSGTYGAMP--------PGSREMETGSPNSLGRSRV 196
Fly 197 DKP-TTYRRSYTHAKPPYSYISLITMAIQNNPTRMLTLSEIYQFIMDLFPFYRQNQQRWQNSIRH 260
Fly 261 SLSFNDCFVKIPRTPDKPGKGSFWTLHPDSGNMFENGCYLRRQKRFKDEKKEAIRQLHKSPSHSS 325
Fly 326 LEATSPGKKDHEDSHHMHHHHHSRLDHHQHHKEAGGASIAGVNVLSAAHSKDAEALAMLHANAEL 390
Fly 391 CLSQQP-----QHVPTHHHHQHHQLQQEELSAMMAN---RCHPSLIT-DYHSSMHPLKQEPSGYT 446
Fly 447 PSSHPFSI---NRLLPTESKADIKMYDMSQYAGYNALSPLTNSHAALGQDSYYQSLGYHAPAGTT 508
Fly 509 SLXHHQYPLAXGRAEQMLRSQQQQHLQQQHQQHQQQQQQHQLHQQQQQMQQSAQQLTSASNTPAT 573
Fly 574 SAKASGKAGSASASGSGSGSGSGSGSNYSQKLQQQHQQQQQQQAAAQQQHHQQ-----------Q 627
Fly 628 QQLLQ-ELQEDSSNITSDLSE----------EQLQQHQAAQQ-QLYNNYQQY------------- 667
Fly 668 -AAAAGY 673 |
Gene | Sequence | Domain | Region | External ID | Identity |
---|---|---|---|---|---|
fkh | NP_001263038.1 | Forkhead_N | <120..209 | CDD:254796 | 23/77 (30%) |
FH | 210..298 | CDD:214627 | 65/87 (75%) | ||
FOXC1 | NP_001444.2 | Required for transcriptional activation. /evidence=ECO:0000269|PubMed:11782474 | 1..51 | 16/46 (35%) | |
FH | 78..166 | CDD:214627 | 65/87 (75%) | ||
Nuclear localization signal 1 (NLS 1). /evidence=ECO:0000269|PubMed:11782474 | 78..93 | 13/14 (93%) | |||
Nuclear localization signal 2 (NLS 2). /evidence=ECO:0000269|PubMed:11782474 | 168..176 | 6/9 (67%) | |||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 173..310 | 30/182 (16%) | |||
Required for transcriptional inhibition. /evidence=ECO:0000269|PubMed:11782474 | 215..366 | 33/191 (17%) | |||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 356..387 | 7/32 (22%) | |||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 414..465 | 7/50 (14%) | |||
Required for transcriptional activation. /evidence=ECO:0000269|PubMed:11782474 | 466..553 | 9/32 (28%) |
Tool | Simple Score | Weighted Score | Original Tool Information | |||
---|---|---|---|---|---|---|
BLAST Result | Score | Score Type | Cluster ID | |||
Compara | 0 | 0.000 | Not matched by this tool. | |||
Domainoid | 0 | 0.000 | Not matched by this tool. | |||
eggNOG | 0 | 0.000 | Not matched by this tool. | |||
Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
Homologene | 0 | 0.000 | Not matched by this tool. | |||
Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
Isobase | 0 | 0.000 | Not matched by this tool. | |||
OMA | 0 | 0.000 | Not matched by this tool. | |||
OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
OrthoFinder | 1 | 1.000 | - | - | FOG0000010 | |
OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
Panther | 0 | 0.000 | Not matched by this tool. | |||
Phylome | 1 | 0.910 | - | - | ||
RoundUp | 0 | 0.000 | Not matched by this tool. | |||
SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
TreeFam | 0 | 0.000 | Not matched by this tool. | |||
User_Submission | 0 | 0.000 | Not matched by this tool. | |||
2 | 1.910 |